Navigation Links
LLS's Lead Therapy Acceleration Program in MDS Gets Boost from Major Industry Licensing Agreement
Date:9/20/2012

WHITE PLAINS, N.Y., Sept. 20, 2012 /PRNewswire/ -- Thanks to support funding from The Leukemia & Lymphoma Society (LLS), Onconova Therapeutics, Inc. has been advancing rigosertib, the lead compound under development for treating patients with high-risk myelodysplastic syndrome (MDS). 

In an announcement made this week, European commercial rights for rigosertib have been licensed to Baxter International providing significant resources to advance the program toward U.S. and European regulatory review and ultimately to MDS patients.  Rigosertib is designed to inhibit critical pathways to the growth and survival of cancer cells. 

"Advancing new therapies in areas of unmet medical need such as MDS is the bow of the ship for LLS," said LLS President and CEO John Walter. "The Baxter/Onconova agreement highlights a successful outcome for the LLS Therapy Acceleration Program (TAP)."

LLS and Onconova first announced their collaboration in June 2010. LLS has committed to providing up to $12.5 million in funding to support an ongoing multicenter, randomized, clinical trial of rigosertib versus best supportive care in adult patients with MDS who have relapsed or become resistant to azacitidine or decitabine. Onconova has announced that, to date, trial enrollment has successfully surpassed the half-way point and there are now 80 trial sites activated around the globe.  Onconova is continuing to accrue patients for the clinical trial.

This partnership marks the first phase 3, approval-track clinical trial that LLS is supporting through TAP, a bold initiative designed to bring promising therapies to patients suffering from blood cancers more quickly.  LLS is taking an active role in accelerating development of novel therapies for patients and&#
'/>"/>

SOURCE The Leukemia & Lymphoma Society
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. StemGenex to Launch Adult Stem Cell-Based Therapy to Relieve COPD Symptoms
2. BioLife Solutions Announces Presentation at IBC Inaugural Cell Therapy Clinical Development Conference
3. Cempra Inc. Presents Additional Data on the Clinical Profile and Activity Spectrum of Solithromycin at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
4. Published Findings In Human Gene Therapy Methods Journal Demonstrate Cardiums New Catheter-Based Method Significantly Boosts Gene Delivery To The Heart
5. New gene therapy strategy boosts levels of deficient protein in Friedreichs ataxia
6. Robert Kirsner, MD, PhD, To Present Results For Phase 2b 6-Month Follow-Up Trial Of Unique Investigational Cell-Based Therapy For Venous Leg Ulcers
7. Genetics Policy Institute (GPI) Collaborates on Second Midwest Conference on Stem Cell Biology and Therapy, Oct. 5-7 at Oakland University
8. First Gene Therapy in Western World Receives Positive Opinion in Europe from CHMP
9. Gold nanoparticles could treat prostate cancer with fewer side effects than chemotherapy
10. Stem Cell Therapy Shown to be Effective in Treating Liver Cirrhosis
11. Californians Take One Step Closer to Directly Accessing Physical Therapy Services for Immediate Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... , Aug. 19, 2014   Synthetic Biologics, ... developing novel anti-infective biologic and drug programs targeting ... announced today that its novel C. difficile ... 54 th Interscience Conference on Antimicrobial Agents ... Washington D.C. Synthetic Biologics, ...
(Date:8/19/2014)... (PRWEB) August 19, 2014 Sales Horizons, ... of its online sales skills training course ... skills. , MedTech clinical staff spend the majority of ... hospital, standalone medical center, or physician practice – providing ... But why stop there? Sales Horizons believes clinical staff ...
(Date:8/18/2014)... Tampa, FL (Aug. 18, 2014) -- A new ... South Florida (USF) Morsani College of Medicine and ... the life-threatening complications of interventional cardiovascular disease treatment. ... model that the novel molecular therapy could selectively ... healing following a medical procedure using a balloon ...
(Date:8/18/2014)... 2014 BioElectronics Corporation (OTC Pink: ... devices said that its EVP Dr. ... as part of its Executive Interview Series. ... at http://ceolive.tv/bioelectronics-corp-otc-biel/biel-videos/2282-ceolive-tv-interview-bioelectronics-corp-otcqb-biel In ... the unique advantages of BioElectronics patented technology ...
Breaking Biology Technology:Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 3Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 4Sales Horizons Launches a New Online Sales Training Course for MedTech Clinical Staff to Develop Their Sales Skills 2Sales Horizons Launches a New Online Sales Training Course for MedTech Clinical Staff to Develop Their Sales Skills 3Selective therapy may improve artery repair after interventional cardiovascular procedures 2Selective therapy may improve artery repair after interventional cardiovascular procedures 3BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 2BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 3
... Mich., Nov. 10 MichBio, the association for,Michigan,s biosciences ... aimed at manufacturers who are looking to diversify into,the ... annual gathering,of biosciences professionals in the state and will ... Novi, MI., Both manufacturing sessions are scheduled for ...
... the Term of the ... ... Processing Ltd.) ( http://www.bsp.co.il/ ), an Israeli company that,develops and markets ... announced that it has signed an,exclusive distribution agreement with CMP Trading ...
... LAS VEGAS, NV, Nov. 10 /PRNewswire-FirstCall/ - Diagnostic ... Company has,entered a purchase agreement to acquire Canadian ... remote readings of MRI,s, CT,PET, CAT and X-rays. ... radiology services to its indigenous community 24hrs per ...
Cached Biology Technology:MichBio Expo Will Feature Sessions for Michigan Manufacturers Interested in Entering Medical Device Market 2BSP Signs Agreement With CMP Trading for Distribution of HyperQ(TM) Stress System, for Early Detection of Ischemic Heart Disease, in South Korea 2Diagnostic Imaging - Enters Purchase Agreement to Acquire Teleradiology Company 2
(Date:8/20/2014)... 20, 2014) Women who are poor experience higher ... with elevated levels of the stress hormone, putting ... life, according to a new research from the University ... in the American Journal of Human Biology , ... relate it directly to the socioeconomic status of their ...
(Date:8/20/2014)... new gene therapy developed by researchers at the University ... protect mice from a life-threatening heart condition caused by ... avenue," said Yi Lai, Ph.D., the leading author of ... School of Medicine,s Department of Molecular Microbiology and Immunology. ... this could lead to a treatment for people with ...
(Date:8/20/2014)... about 4,000 members, it triggers an important first stage ... type of comb used for rearing male reproductive, called ... Neurobiology and Behaviour at Cornell University, led by Michael ... colonies. The results are published in Springer,s journal ... Reproduction isn,t always a honeybee colony,s top priority. ...
Breaking Biology News(10 mins):CU Denver researcher shows economic disparities impact infant health 2Gene therapy protects mice from lethal heart condition, MU researchers find 2Worker bees 'know' when to invest in their reproductive future 2
... and parasitoids, has been going on for more than 34 ... protected area of approximately 1200 km2 in northwestern Costa Rica. ... butterflies are estimated to live in ACG. Their caterpillars are ... of species. However, most of those wasps have never been ...
... Engineering (NCE) at New Jersey Institute of Technology (NJIT) will host ... in the Campus Center Atrium. Proceeds from the event will ... NCE Dean,s Fund. "NCE has a long tradition ... them hands-on experiences along the way," said Interim Dean Basil C. ...
... from Uppsala University shows that saturated fat builds more fat ... study on humans to show that the fat composition of ... the risk of cardiovascular disease but also determines where the ... recently been published in the American journal Diabetes . ...
Cached Biology News:Almost 200 new species of parasitoid wasps named after local parataxonomists in Costa Rica 2NJIT's Newark College of Engineering announces honorees for annual Salute to Excellence 2NJIT's Newark College of Engineering announces honorees for annual Salute to Excellence 3Abdominal fat accumulation prevented by unsaturated fat 2Abdominal fat accumulation prevented by unsaturated fat 3
...
The Discovery Series PDQuest 2-D analysis software is used for imaging, analyzing, and databasing two-dimensional electrophoretic gels. The 10-user network license entitles ten users to access data f...
Mouse monoclonal antibody raised against a partial recombinant JRKL. NCBI Entrez Gene ID = JRKL...
Mouse monoclonal antibody to ST8SIA2 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2...
Biology Products: