Navigation Links
LLS's Lead Therapy Acceleration Program in MDS Gets Boost from Major Industry Licensing Agreement
Date:9/20/2012

WHITE PLAINS, N.Y., Sept. 20, 2012 /PRNewswire/ -- Thanks to support funding from The Leukemia & Lymphoma Society (LLS), Onconova Therapeutics, Inc. has been advancing rigosertib, the lead compound under development for treating patients with high-risk myelodysplastic syndrome (MDS). 

In an announcement made this week, European commercial rights for rigosertib have been licensed to Baxter International providing significant resources to advance the program toward U.S. and European regulatory review and ultimately to MDS patients.  Rigosertib is designed to inhibit critical pathways to the growth and survival of cancer cells. 

"Advancing new therapies in areas of unmet medical need such as MDS is the bow of the ship for LLS," said LLS President and CEO John Walter. "The Baxter/Onconova agreement highlights a successful outcome for the LLS Therapy Acceleration Program (TAP)."

LLS and Onconova first announced their collaboration in June 2010. LLS has committed to providing up to $12.5 million in funding to support an ongoing multicenter, randomized, clinical trial of rigosertib versus best supportive care in adult patients with MDS who have relapsed or become resistant to azacitidine or decitabine. Onconova has announced that, to date, trial enrollment has successfully surpassed the half-way point and there are now 80 trial sites activated around the globe.  Onconova is continuing to accrue patients for the clinical trial.

This partnership marks the first phase 3, approval-track clinical trial that LLS is supporting through TAP, a bold initiative designed to bring promising therapies to patients suffering from blood cancers more quickly.  LLS is taking an active role in accelerating development of novel therapies for patients and&#
'/>"/>

SOURCE The Leukemia & Lymphoma Society
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. StemGenex to Launch Adult Stem Cell-Based Therapy to Relieve COPD Symptoms
2. BioLife Solutions Announces Presentation at IBC Inaugural Cell Therapy Clinical Development Conference
3. Cempra Inc. Presents Additional Data on the Clinical Profile and Activity Spectrum of Solithromycin at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
4. Published Findings In Human Gene Therapy Methods Journal Demonstrate Cardiums New Catheter-Based Method Significantly Boosts Gene Delivery To The Heart
5. New gene therapy strategy boosts levels of deficient protein in Friedreichs ataxia
6. Robert Kirsner, MD, PhD, To Present Results For Phase 2b 6-Month Follow-Up Trial Of Unique Investigational Cell-Based Therapy For Venous Leg Ulcers
7. Genetics Policy Institute (GPI) Collaborates on Second Midwest Conference on Stem Cell Biology and Therapy, Oct. 5-7 at Oakland University
8. First Gene Therapy in Western World Receives Positive Opinion in Europe from CHMP
9. Gold nanoparticles could treat prostate cancer with fewer side effects than chemotherapy
10. Stem Cell Therapy Shown to be Effective in Treating Liver Cirrhosis
11. Californians Take One Step Closer to Directly Accessing Physical Therapy Services for Immediate Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Corporation (NASDAQ: NEOG ) announced today that ... 31, increased 19% from the previous year to $247,405,000. ... prior year,s $27,190,000. Adjusted for a 3-for-2 stock split ... current year were $0.76, compared to $0.75 a year ... fiscal year established new all-time highs for the 32-year-old ...
(Date:7/22/2014)... CAMBRIDGE, Massachusetts en SHENZHEN, China ... Solutions Co., LTD, (BGI Tech), een dochtermaatschappij van BGI, ... kondigde de wereldwijde introductie aan van een nieuwe service ... de sector meest geavanceerde platform van Complete Genomics. ... bedrijf dat binnen de sector in hoog aanzien staat ...
(Date:7/22/2014)... In chemical and petrochemical plants, ... sight. The rapid rise of TDL analyzers over ... as a core gas measurement technology, and their ... the gas analyzer technology of choice for many ... some processes have limited their application range. METTLER ...
(Date:7/22/2014)... WA (PRWEB) July 22, 2014 Quorum Review ... new service for large clinical trials called Quick Step™ ... is designed to address the research industry’s need for seamless ... The service is available for studies planning 50 or more ... a combined planned North American site count of 80 or ...
Breaking Biology Technology:Neogen reports 19% increase in annual revenues 2Neogen reports 19% increase in annual revenues 3Neogen reports 19% increase in annual revenues 4Neogen reports 19% increase in annual revenues 5Neogen reports 19% increase in annual revenues 6Neogen reports 19% increase in annual revenues 7Neogen reports 19% increase in annual revenues 8BGI Tech introduceert service op gebied van hele menselijke exoomsequencing op geavanceerd Complete Genomics-platform 2METTLER TOLEDO Shows How Tunable Diode Lasers (TDLs) Can Be Installed Where No TDLs Have Gone Before 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 3
... Gov. Jim Doyle , whose "Grow Wisconsin" economic development ... state, has signed a bill that removes from the ... to capital formation , ,With little fanfare, Doyle signed ... the Wisconsin Economic Development Association. The law repeals a ...
... Something that was always taken for granted was the quality ... Sprint commercials, they emphasized that "you can hear a pin ... infrastructure. , ,The old Bell system also had very ... from analog to digital lines with digital repeaters (amplifiers) that ...
... Wis. - Tundra Semiconductor Corp. , the ... and computing markets, has announced the acquisition of ... company based in Eau Claire, for $14 million. , ... as a division of Tundra Semiconductor Corp. The company ...
Cached Biology Technology:Doyle repeals shareholder liability 2Is traditional voice quality an oxymoron with today's cellular, VoIP? 2Is traditional voice quality an oxymoron with today's cellular, VoIP? 3Canadian firm acquires Silicon Logic 2
(Date:7/22/2014)... July 22, 2014 BGI Tech Solutions Co., ... world,s largest genomics organization, announced today the global ... service based on Complete Genomics, industry-leading platform. This ... SNP validation, and is available at reduced prices ... highly regarded in the industry for providing proprietary ...
(Date:7/22/2014)... spot with natural tourism resources, a recent study revealed a ... Geoscience and Mineral Resources (KIGAM) indicated that there are the ... 5,000 years ago. That is the first time to actually ... volcano 5,000 years ago in the inland part of the ... The research team led by Dr. Jin-Young Lee confirmed in ...
(Date:7/22/2014)... type of immune cell widely believed to exacerbate ... and multiple sclerosis (MS), can actually protect the ... slow the progression of neurodegenerative diseases, according to ... journal Nature Communications . , The research ... the Department of Neurosciences at Cleveland Clinic,s Lerner ...
Breaking Biology News(10 mins):BGI Tech launches human whole exome sequencing service on complete genomics' advanced platform 2Jeju Island is a live volcano 2Cleveland Clinic researchers discover neuroprotective role of immune cell 2
... that commonly develop in early infancy are generally ... or destruction and sometimes obstruction of vision or breathing. ... corticosteroids such as dexamethasone or prednisone. But steroids have ... of action in hemangioma has remained a mystery. Researchers ...
... engineering researchers have found they can ignite certain nanoparticles using ... to a wave of new technologies in health care, computing ... in this week,s advance online edition of Nature Nanotechnology ... Moudgil say they used lasers not much more intense than ...
... Plants can,t escape from stressful environments, but they can ... shifting rainfall patternsboth likely to become more common under ... discuss one system that plants use to cope with ... the Smithsonian Tropical Research Institute at the Earl S. ...
Cached Biology News:Stem cells used to model infant birth defect 2Stem cells used to model infant birth defect 3Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 2Engineers: Weak laser can ignite nanoparticles, with exciting possibilities 3Smithsonian hosts 2010 International CAM Workshop in Panama 2
biotin-4-fluorescein...
... the LVF-HL, LVF-CUVADPT, FHS-LVF, and the CVD-Diffuse ... low-pass Linear Variable Filters to create the ... center wavelength and adjustable bandpass. Each filter ... blocking band (99.8%). These filters -- ...
BBS/Glycerol/Casein Block and Diluent - 10X Concentrate, 1 L...
Request Info...
Biology Products: