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Kinase Inhibitors: Global Markets -- Focus on the U.S.
Date:9/6/2012

nhibitors 16

TABLE 7 TYPES OF NON-RECEPTOR TYROSINE KINASE INHIBITORS 16

CLASSIFICATION BY SITE OF ACTION 17

TABLE 8 CLASSIFICATION OF KINASE INHIBITORS BY SITE OF ACTION 17

CHAPTER 4 REGULATORY ASPECTS 20

TABLE 9 FDA-APPROVED KINASE INHIBITORS, 2008 TO FEBRUARY 2012 20

TABLE 10 EMA-APPROVED KINASE INHIBITORS 2008 TO FEBRUARY 2012 21

TABLE 11 SAFETY ALERTS AND WARNINGS FOR KINASE INHIBITORS 2008 TO FEBRUARY

2012 22

TABLE 12 NEW DRUG APPLICATIONS OF KINASE INHIBITORS 23

MARKET LEADERS AND THEIR PRODUCTS FOR KINASE INHIBITORS 24

TABLE 13 LEADING MANUFACTURERS AND SUPPLIERS OF RECEPTOR TYROSINE KINASE

INHIBITORS 24

TABLE 14 LEADING MANUFACTURERS AND SUPPLIERS OF NON-RECEPTOR TYROSINE

KINASE INHIBITORS 24

TABLE 15 LEADING MANUFACTURERS AND SUPPLIERS OF MULTI-TARGET TYROSINE

KINASE INHIBITORS 24

TABLE 16 LEADING MANUFACTURERS AND SUPPLIERS OF SERINE AND THREONINE

KINASE INHIBITORS 25

TABLE 17 LEADING MANUFACTURERS AND SUPPLIERS OF ANTIBODY KINASE INHIBITORS 25

CHAPTER 5 NEW DEVELOPMENTS 27

(RECEPTOR) TYROSINE KINASE INHIBITORS (TKIS) 27

TABLE 18 CLINICAL TRIALS IN EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TKIS 27

TABLE 19 CLINICAL TRIALS IN HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER2)

TKIS 28

TABLE 20 CLINICAL TRIALS IN PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR)

TKIS 28

TABLE 21 CLINICAL TRIALS IN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR

(VEGFR) TKIS 28

(NON-RECEPTOR) TYROSINE KINASE INHIBITORS (TKIS) 29

TABLE 22 CLINICAL TRIALS IN BCR-ABL TYROSINE KINASE INHIBITORS 29

TABLE 23 CLINICAL TRIALS IN JANUS KINASE (JAK) INHIBITORS 29

TABLE 24 CLINICAL TRIALS IN SPLEEN TYROSINE KINASE (SYK) INHIBITORS 29

MULTIKINASE INHIBITORS 30

TABLE 25 CLINICAL TRIALS IN MULTIKINASE INHIBITORS 30

SERINE/THREONINE KINASE INHIBITOR 31

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