Navigation Links
Keystone Nano Announces Progress On RNA Delivery
Date:4/11/2017

STATE COLLEGE, Pa., April 11, 2017 /PRNewswire/ -- Keystone Nano, Inc. (KN), a clinical stage biopharmaceutical company focused on improving cancer treatments through the application of nanotechnology, announced today significant progress on the delivery of RNA using NanoJackets (NJs).  KN's NanoJackets are proprietary, customizable calcium phosphate nanoparticles that protect the active agent in the bloodstream and deliver it to targeted cells.  Key recent achievements include:

  • substantial new knowledge on encapsulating various kinds of RNA including siRNA, micro RNA and messenger RNA,
  • improved knowledge about the safety/toxicity of the NanoJacketed RNA,
  • new understanding of bio-distribution after administration by injection or inhalation, and
  • greater knowledge about the length of time RNA-NanoJackets work within the body

KN is working to optimize the therapeutic activity of RNA both for the internal programs and for pharmaceutical client companies.  KN has found that working with NanoJackets to encapsulate and deliver the different types of RNA requires different approaches for each.  However, in all cases, KN's RNA-NanoJackets have shown that they contain substantial amounts of RNA, are composed of safe and well tolerated materials, protect the RNA from degradation in the blood stream and can be targeted to specific cell types.

Several new breakthrough therapies anticipate using the different types of RNA to halt disease progression – either by silencing select RNA processes associated with disease, or by using RNA to code for production of therapeutic molecules within the body itself.  The increasing interest in RNA therapy has led to a need for a safe, effective and efficient method to deliver RNA.  KN's calcium phosphate NanoJackets offer a highly biocompatible, non-toxic and effective solution to that problem.

KN's work in RNA delivery has been supported by grants from the National Cancer Institute, the National Institute for Allergies and Infectious Diseases, and the Pennsylvania Department of Health.  KN's work in RNA delivery builds on work at Penn State and the University of Virginia. Jeff Davidson, KN's CEO, noted: "our research team has made great progress building powerful new ways to deliver RNA.  Our goal is to continue this work to further improve human health."

About Keystone Nano, Inc.  KNs lead product, Ceramide NanoLiposome, entered clinical testing in early 2017.  For more information visit www.keystonenano.com.

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/keystone-nano-announces-progress-on-rna-delivery-300437963.html


'/>"/>
SOURCE Keystone Nano, Inc.
Copyright©2017 PR Newswire.
All rights reserved


Related biology technology :

1. Keystone Nano Announces Start Of Clinical Testing Of Ceramide NanoLiposome For The Improved Treatment Of Cancer
2. Applied BioMath, LLC presents work in immuno-oncology and antibody drug-conjugates at Keystone Symposium
3. MaxCyte, Inc. to Present Pre-Clinical Data for Targeted Gene-Correction in a Rare Disease at Keystone Symposia on Precision Genome Engineering
4. University City Keystone Innovation Zone Expands to Old City, N3rd Street Startup Community
5. Keystone Symposia Announces Grant from Alfred P. Sloan Foundation for an Advanced Life Sciences Training Program
6. Greater Gift Initiative Announces Partnership with INC Research
7. Axovant Sciences Ltd. Announces $100 Million Public Offering of Common Shares
8. Bioptix Announces Executive Leadership Change
9. Nerium International announces expansion into New Zealand
10. Charm Sciences Announces New Sales/Business Manager
11. BIOARRAY Genetics Inc. Announces the Launch of a Novel Oncology Gene Panel
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2018)... Calif. (PRWEB) , ... October 18, 2018 , ... ... CLIA-certified genomic sequencing laboratory in the San Francisco Bay Area has received accreditation ... quality, operations, and patient safety. , Predicine received CAP accreditation for its Shanghai ...
(Date:10/17/2018)... ... 2018 , ... PathSensors’ cutting-edge CANARY based assays for the ... and Plant Health Inspection Service for use in regulatory diagnostics. By going through ... they will be able to rapidly and accurately test and identify these damaging ...
(Date:10/16/2018)... ... , ... The American Medical Informatics Association (AMIA) is proud to announce the ... the AMIA 2018 Annual Symposium , taking place Nov. 3 – 7, in ... more than 700 submissions. The AMIA Signature Awards program provides an opportunity for AMIA ...
(Date:10/11/2018)... Calif. (PRWEB) , ... October 11, 2018 , ... ... and short-run label printing and software solutions, in collaboration with HP, the global ... certification for Avery UltraDuty GHS Chemical Labels on all HP PageWide Printers. , ...
Breaking Biology Technology:
(Date:10/11/2018)... ... October 09, 2018 , ... ? Smart Health Innovation Lab’s ... path to health system adoption and insurer reimbursement, ? Redox’s integration platform helps ... applications, enabling them to focus on innovation not integration, ? By gaining access ...
(Date:10/11/2018)... ... ... The American College of Medical Informatics (ACMI) will present the 2018 Morris ... National Library of Medicine (NLM), during the Opening Session of the AMIA 2018 ... – 7. , In honor of Morris F. Collen, a pioneer in the field ...
(Date:10/5/2018)... , ... October 04, 2018 , ... EDETEK, the premier ... at the CDISC U.S. Interchange in Bethesda, MD on October 8-12, 2018. EDETEK is ... City, CA on November 5-6, 2018. , CDISC Interchanges are global events held ...
Breaking Biology News(10 mins):