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Keryx Biopharmaceuticals, Inc. Enters into Licensing Agreement with Japan Tobacco and Torii Pharmaceutical for Development and Commercialization of Hyperphosphatemia Drug in Japan
Date:9/26/2007

tion. Japan is the 2nd largest national ESRD market after the United States with approximately 250,000 patients receiving dialysis.

Keryx holds a worldwide license (except for the Asian Pacific Region, but including Japan) to Zerenex(TM) from Panion & BF Biotech, Inc. Keryx is actively engaged in the development of Zerenex(TM) for the United States and is considering additional potential sublicenses in other parts of the world. Zerenex(TM), an oral, iron-based compound that has the capacity to bind to phosphorous and form non-absorbable complexes, has the potential to be an effective and safe treatment in lowering and/or maintaining serum phosphorus levels <5.5 mg/dL in patients with ESRD and hyperphosphatemia.

"We are pleased to have entered into this relationship with JT and Torii," stated Michael S. Weiss, Chairman and CEO of Keryx, who continued, "They have proven themselves to be ideal partners for smaller U.S.-based biotechnology companies seeking development and commercial partners in Japan. We are excited that they have chosen our phosphate binder for commercialization in Japan. We are committed to bringing forward globally this novel product and we are confident that by working together with JT and Torii we will be successful in bringing this valuable treatment option to patients in Japan."

"This arrangement with JT and Torii confirms our belief that there is a significant need for a novel phosphate binder like Zerenex(TM) and we look forward to working with our new partners moving the product forward in Japan," stated Ken Hoberman, head of Business Development for Keryx.

About Keryx Biopharmaceuticals, Inc.

Keryx Biopharmaceuticals, Inc. is focused on the acquisition, development and commercialization of medically important, novel pharmaceutical products for the treatment of life-threatening diseases, including diabetes and cancer. Keryx's lead compound under development is Sulonex(TM) (sulodexide), previously referred to as K
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SOURCE Keryx Biopharmaceuticals, Inc.
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