el
pharmaceutical products for the treatment of life-threatening diseases,
including diabetes and cancer. Keryx's lead compound under development is
Sulonex(TM) (sulodexide), previously referred to as KRX-101, a
first-in-class, oral heparinoid compound for the treatment of diabetic
nephropathy, a life-threatening kidney disease caused by diabetes. Sulonex
is in a pivotal Phase III and Phase IV clinical program under a Special
Protocol Assessment with the Food & Drug Administration. Additionally,
Keryx is developing Zerenex(TM), an oral, inorganic, iron-based compound
that has the capacity to bind phosphate and form non-absorbable complexes.
Zerenex is currently in Phase II clinical development for the treatment of
hyperphosphatemia (elevated serum phosphorous levels) in patients with end-
stage renal disease. Keryx is also developing clinical-stage oncology
compounds, including KRX-0401 (perifosine), a novel, first-in-class, oral
anti-cancer agent that inhibits activation of Akt, a protein in the body
associated with tumor survival and growth, and modulates a number of other
key signal transduction pathways. KRX-0401 is currently in Phase II
clinical development for multiple tumor types. Keryx also has an active
in-licensing and acquisition program designed to identify and acquire
additional drug candidates. Keryx is headquartered in New York City.
Cautionary Statement
Some of the statements included in this press release and made by our
management on the conference call, particularly those anticipating future
financial performance, clinical and business prospects for our lead drug
candidates Sulonex, Zerenex and KRX-0401, growth and operating strategies
and similar matters, may be forward-looking statements that involve a
number of risks and uncertainties. For those statements, we claim the
protection of the safe harbor for forward-looking statements contained in
the Private Securities Litigation Reform Act of 1995. Among the factors
that could cause ou
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SOURCE Keryx Biopharmaceuticals, Inc. Copyright©2007 PR Newswire. All rights reserved | |
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