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KRAS Diagnostic Test That Assists With Personalized Treatment of Colorectal Cancer Receives CE Mark
Date:7/21/2011

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About the cobas KRAS Mutation Test and the cobas 4800 System, v2.0

The cobas KRAS Mutation Test is a TaqMelt™, polymerase chain reaction-based diagnostic test intended for the detection of mutations in codons 12, 13 and 61 of the KRAS gene. The cobas KRAS Mutation Test is now commercially available in countries that recognize the CE mark.

The cobas 4800 System v2.0 offers high-performance amplification and detection coupled with software that automates thermal cycling conditions, results interpretation, analysis and reporting. The cobas 4800 System v1.1 was recently approved in the US and all countries accepting a CE mark.

About Roche

Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world's largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche's personalized healthcare strategy aims at providing medicines and diagnostic tools that enable tangible improvements in the health, quality of life and survival of patients. In 2009, Roche had over 80,000 employees worldwide and invested almost 10 billion Swiss francs in R&D. The Group posted sales of 49.1 billion Swiss francs. Genentech, United States, is a wholly owned member of the Roche Group. Roche has a majority stake in Chugai Pharmaceutical, Japan. For more information: www.roche.com.

All trademarks used or mentioned in this release are legally protected by law.

(1) Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal grow
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SOURCE Roche Molecular Systems, Inc.
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