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Johnson & Johnson Honors 2009 Recipient of The Dr. Paul Janssen Award for Biomedical Research
Date:9/8/2009

vel cancer therapy, culminating in the production of an anti-HER2 monoclonal antibody that since 1998 has been used successfully to treat patients with metastatic breast cancer. This was the first targeted drug developed on the basis of a newly discovered gene associated with a cancer causing function in humans.

In the early 1990s, Ullrich identified the signaling system involved in regulating tumor angiogenesis, the growth of blood vessels in tumors. He discovered that inhibiting a key player in the signaling system (called vascular endothelial growth factor receptor or VEGFR) suppresses the generation of blood vessels in tumors and slows down cancer cell growth. Years later, a small molecule inhibitor of the VEGFR2 kinase function was developed, from which a derivative was approved in 2006 for the treatment of kidney carcinoma and gastro-intestinal stromal tumors.

"It is an honor to be recognized with an award of this stature," said Ullrich. "Dr. Paul was a highly respected scientist whose work continues to extend and improve the lives of people all over the world. I am truly humbled to be selected as the recipient of an award whose namesake carries on his tremendous legacy."

"Dr. Ullrich is one of the few basic scientists whose work directly affects the lives of countless patients suffering from major chronic diseases," said Paul Stoffels, M.D., global head, Research & Development, Pharmaceuticals, Johnson & Johnson. "We are proud to present The Dr. Paul Janssen Award to such a passionate pioneer in biomedical research."

Ullrich has previously received prestigious honors and awards, including the Robert Koch Prize, the Bruce F. Cain Memorial Award of the American Association of Cancer Research and the King Faisal Prize of Medicine.

About The Dr. Paul Janssen Award

Established by Johnson & Johnson, The Dr. Paul Ja
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