Navigation Links
'Jet-lagged' fruit flies provide clues for body clock synchronisation
Date:1/17/2013

New research led by a team at Queen Mary, University of London, has found evidence of how daily changes in temperature affect the fruit fly's internal clock.

"A wide range of organisms, including insects and humans, have evolved an internal clock to regulate daily patterns of behaviour, such as sleep, appetite, and attention," explains Professor Ralf Stanewsky, senior study author from Queen Mary's School of Biological and Chemical Sciences.

"Research on animal and human clocks shows that they are fine tuned by natural and man-made time cues, for example the daily changes of light and temperature, alarm clocks and 'noise-pollution'. Understanding the principles of clock synchronisation could be useful in developing treatments against the negative effects of sleep-disorders and shift-work. This research has many implications because it extends our knowledge of how the environment influences body clocks."

Scientists have a good understanding of how light affects the internal body clock, also known as the circadian clock. Specially evolved cells in the brain contain the circadian clock, which needs to be synchronised with the natural environment every day to help them run on time.

In this new study, the researchers made groups of fruit flies 'jet-lagged' by exposing them to daily temperature changes reflecting warmer or colder climates to understand how temperature affects the circadian clock.

The team discovered that a group of 'dorsal clock cells' found in the back of the fly's brain was more important for clock-synchronisation at warmer temperatures. But a group of ventral clock cells found further to the front of the brain played an important role at the cooler temperature range. In addition to their clock function, these cells also act like a thermometer, being more active at certain temperatures.

The research also shows that removing the light-receptor Cryptochrome, an important component in synchronising the clock to the daily light changes, leads to the flies being more sensitive to temperature changes. This could help to explain why daily light changes, which are a more reliable time cue compared to the daily temperature fluctuations, are the dominant signal in nature for synchronising the clock.


'/>"/>
Contact: Neha Okhandiar
n.okhandiar@qmul.ac.uk
020-788-27927
Queen Mary, University of London
Source:Eurekalert

Related biology technology :

1. Some Bilberry Fruit Extracts Adulterated, says Nonprofit Research Consortium
2. Syracuse University researchers use nanotechnology to harness power of fireflies
3. New Resource Provides Herb Industry With Sources of Quality Specifications
4. inVentiv Health Selected to Provide Sales Operations Support for Santarus
5. Amsterdam Molecular Therapeutics Provides Business Update for the Third Quarter 2011
6. Generex Provides Update on Generex Oral-lyn™ Clinical & Regulatory Program
7. Health Diagnostic Laboratory, Inc. Provides Largest Corporate Gift in Science Museum of Virginias History
8. Generex Subsidiary Antigen Express Provides Update on AE37 Cancer Vaccines Clinical & Regulatory Strategy
9. Elsevier Acquires QUOSA, Provider of Life Sciences Content Management and Workflow Productivity Solutions
10. Oxford Finance Provides $15 Million Senior Secured Credit Facility to Private Equity Backed Healthcare Services Company
11. Insmed Incorporated Provides Corporate Update
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting in North ... in Harvard University’s Departments of Physics and Astronomy, has been selected for membership in ... winning team for the 2015 Breakthrough Prize in Fundamental physics for the discovery of ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... consulting for microscopy and surface analysis, Nanoscience Instruments is now expanding into ... a broad range of contract analysis services for advanced applications. Services will ...
(Date:10/6/2017)... ... October 06, 2017 , ... The HealthTech Venture Network ... at their fourth annual Conference where founders, investors, innovative practitioners and collaborators are ... pitch competition showcasing early stage digital health and med tech companies. , This ...
(Date:10/5/2017)... ... 2017 , ... Understanding the microbiome, the millions of bacteria that live in ... Are My Future, the newest exhibit on display at the University City Science Center’s ... through the lens of the gut microbiome. , Gut Love opens October 12, ...
Breaking Biology Technology:
(Date:8/15/2017)...   ivWatch LLC , a medical device company focused on ... receipt of its ISO 13485 Certification, the global standard for medical ... Standardization (ISO®). ... Continuous Monitoring device for the early detection of IV infiltrations. ... "This is an important milestone for ivWatch, as ...
(Date:6/30/2017)... ARLINGTON, Va. , June 30, 2017 /PRNewswire-USNewswire/ ... a leading developer and supplier of face and ... the ATA Featured Product provider program. ... created an innovative way to monitor a driver,s ... benefit greatly from being able to detect fatigue ...
(Date:6/14/2017)... 15, 2017  IBM (NYSE: IBM ) is introducing several ... dedicated to developing collaboration between startups and global businesses, taking ... During the event, nine startups will showcase the solutions they ... industries. France is ... with a 30 percent increase in the number of startups ...
Breaking Biology News(10 mins):