Navigation Links
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
Date:10/24/2009

Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

Chicago, IL (Vocus) October 21, 2009 -- Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

The data presented at the prestigious conference highlights the continuing story of an unusual compound making its presence known in the field of neuroscience. “Stroke is used in the laboratory because the model replicates a biochemical process in a few minutes what neurodegeneration takes years to do and gives us a good idea of a compound’s neuroprotective ability.” explains Mark Underwood, Quincy Bioscience president.

The neuroscience pipeline for drug development has been lacking significant breakthroughs for several years. “The bar for Alzheimer’s drugs is not very high. The existing approved drugs for Alzheimer’s have provided a small amount of improvement for the lives of patients and caregivers.”

According to the calcium hypothesis of brain aging, one of the reasons for reasons for neurodegeneration is the brain cell’s inability to regulate calcium ions. Calcium binding proteins (CaBPs) are intracellular proteins that help regulate calcium. Their decline is gradual in normal aging and is believed to contribute to elevated calcium ion levels which in turn affect brain function. Conversely, in neurodegeneration, CaBP production declines rapidly and contributes to cell death.

For people over forty years of age it is estimated that 30,000 – 50,000 brain cells die each day which can lead to cognitive challenges such as an impaired ability to learn and retain new information as well as memory loss.

Aequorin is a naturally-occurring CaBP and was first discovered in glowing jellyfish in the Puget Sound by Princeton researcher Osamu Shimomura, Ph.D. in 1962. Dr. Shimomura was one of the recipients of the Nobel Prize in Chemistry 2008 for the discovery and development of this protein for the advancement in calcium research. Aequorin’s DNA structure is very similar to the CaBPs produced in the brain. Quincy Bioscience has patent-filings for the novel use of Aequorin for the purposes of neuronal calcium regulation.

ABOUT QUINCY BIOSCIENCE
Quincy Bioscience is a biotech company located in Madison, Wisconsin focused on the discovery, development and commercialization of novel medicines to treat age related memory loss and the diseases of aging. The company's therapeutic focus is on alleviating the consequences of impaired calcium homeostasis - the imbalance of calcium ions thought to be related to neurodegenerative diseases such as Alzheimer's and Parkinson's.

# # #

Read the full story at http://www.prweb.com/releases/Brain/Health/prweb3090774.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related biology technology :

1. Jellyfish Protein Shows Potential to Help With Memory
2. Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease
3. China-Biotics, Inc. Launches Shining Probiotics Protein Powder
4. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
5. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
6. New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrines Anti-PS Technology Platform
7. Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio
8. Decision Biomarkers Awarded U.S. Patent for Protein Array Surface Chemistry
9. STALLERGENES and Protein eXpert Enter Into a Partnership for Producing Mites Recombinant Allergens
10. Alfacell Announces ONCONASE(R) Purchase and Supply Agreement with Scientific Protein Laboratories
11. Decision Biomarkers Launches System for Faster, Easier Quantification of Protein Biomarkers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
(Date:8/21/2017)... ... August 21, 2017 , ... Baltimore biotech firm, PathSensors, ... to bring its proprietary CANARY pathogen detection technology and high throughput testing solutions ... has purchased an undisclosed number of PathSensors’ Zephyr pathogen detection instruments and will ...
(Date:8/21/2017)... ... August 21, 2017 , ... ... speakers for this two-part educational webinar, in which attendees will learn about the ... protein factor composition. Along with an overview of the development and validation of ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... they will feature Federal Hybrids, Inc. in an upcoming episode, scheduled to broadcast ... American Farmer will explore Federal Hybrids, the independent, family-owned seed company. Educating audiences ...
(Date:8/17/2017)... ... August 17, 2017 , ... ... news outlet had provided a research update on Aytu Bioscience and cited promising ... , According to Soulstring, prescription rates for Natesto® have more than doubled since ...
Breaking Biology Technology:
(Date:4/3/2017)... WASHINGTON , April 3, 2017 /PRNewswire-USNewswire/ ... single-cell precision engineering platform, detected a statistically ... cell product prior to treatment and objective ... highlight the potential to predict whether cancer ... prior to treatment, as well as to ...
(Date:3/30/2017)... , March 30, 2017 Trends, opportunities ... (physiological and behavioral), by technology (fingerprint, AFIS, iris recognition, ... recognition, and others), by end use industry (government and ... immigration, financial and banking, and others), and by region ... , Asia Pacific , and ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
Breaking Biology News(10 mins):