Navigation Links
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
Date:10/24/2009

Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

Chicago, IL (Vocus) October 21, 2009 -- Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

The data presented at the prestigious conference highlights the continuing story of an unusual compound making its presence known in the field of neuroscience. “Stroke is used in the laboratory because the model replicates a biochemical process in a few minutes what neurodegeneration takes years to do and gives us a good idea of a compound’s neuroprotective ability.” explains Mark Underwood, Quincy Bioscience president.

The neuroscience pipeline for drug development has been lacking significant breakthroughs for several years. “The bar for Alzheimer’s drugs is not very high. The existing approved drugs for Alzheimer’s have provided a small amount of improvement for the lives of patients and caregivers.”

According to the calcium hypothesis of brain aging, one of the reasons for reasons for neurodegeneration is the brain cell’s inability to regulate calcium ions. Calcium binding proteins (CaBPs) are intracellular proteins that help regulate calcium. Their decline is gradual in normal aging and is believed to contribute to elevated calcium ion levels which in turn affect brain function. Conversely, in neurodegeneration, CaBP production declines rapidly and contributes to cell death.

For people over forty years of age it is estimated that 30,000 – 50,000 brain cells die each day which can lead to cognitive challenges such as an impaired ability to learn and retain new information as well as memory loss.

Aequorin is a naturally-occurring CaBP and was first discovered in glowing jellyfish in the Puget Sound by Princeton researcher Osamu Shimomura, Ph.D. in 1962. Dr. Shimomura was one of the recipients of the Nobel Prize in Chemistry 2008 for the discovery and development of this protein for the advancement in calcium research. Aequorin’s DNA structure is very similar to the CaBPs produced in the brain. Quincy Bioscience has patent-filings for the novel use of Aequorin for the purposes of neuronal calcium regulation.

ABOUT QUINCY BIOSCIENCE
Quincy Bioscience is a biotech company located in Madison, Wisconsin focused on the discovery, development and commercialization of novel medicines to treat age related memory loss and the diseases of aging. The company's therapeutic focus is on alleviating the consequences of impaired calcium homeostasis - the imbalance of calcium ions thought to be related to neurodegenerative diseases such as Alzheimer's and Parkinson's.

# # #

Read the full story at http://www.prweb.com/releases/Brain/Health/prweb3090774.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related biology technology :

1. Jellyfish Protein Shows Potential to Help With Memory
2. Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease
3. China-Biotics, Inc. Launches Shining Probiotics Protein Powder
4. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
5. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
6. New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrines Anti-PS Technology Platform
7. Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio
8. Decision Biomarkers Awarded U.S. Patent for Protein Array Surface Chemistry
9. STALLERGENES and Protein eXpert Enter Into a Partnership for Producing Mites Recombinant Allergens
10. Alfacell Announces ONCONASE(R) Purchase and Supply Agreement with Scientific Protein Laboratories
11. Decision Biomarkers Launches System for Faster, Easier Quantification of Protein Biomarkers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
(Date:1/19/2017)... ... January 19, 2017 , ... November ... to leading biopharmaceutical and medical device manufacturers and regulators, is proud to announce ... Part 11-compliant email client designed to provide product vigilance departments with the flexibility ...
(Date:1/19/2017)... ... 2017 , ... The American Medical Informatics Association (AMIA) today ... Policy. Specifically, the nation’s leading informatics experts, said data sharing plans should be ... recommended that NIH earmark funding for researchers to produce and execute data sharing ...
(Date:1/19/2017)... Jan. 18, 2017 The global biotechnology ... 92.9 billion by 2025, according to a new ... has been adaptive of the function of outsourcing ... 2002. Among the services outsourced, clinical trial management ... Johnson & Johnson was the first pharmaceutical company ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... device-to-computer interconnect using USB or PCI Express, announced the ZEM5310 USB 3.0 FPGA ... FPGA into a compact business-card sized form factor suitable for prototyping, testing, and ...
Breaking Biology Technology:
(Date:12/19/2016)... España y TORONTO , 19 de diciembre de ... Biologics Inc. que permitirá el desarrollo acelerado de MSC-1, un anticuerpo ... varios tipos de tumor en 2017, con múltiples sitios previstos a ... ... con objetivo en el factor inhibidor de leucemia (LIF), una citoquina ...
(Date:12/16/2016)... Research and Markets has announced the addition of the ... report to their offering. ... The biometric vehicle access system market, in terms of ... 2016 to 2021. The market is estimated to be USD 442.7 ... 2021. The growth of the biometric vehicle access system market is ...
(Date:12/15/2016)... and BADEN-BADEN, Germany , December ... leading global financial services provider, today announced an agreement with ... behavioural biometrics, to join forces. The partnership will enable clients ... strategies in compliance with local data protection regulation. ... In order to ...
Breaking Biology News(10 mins):