Navigation Links
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
Date:10/24/2009

Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

Chicago, IL (Vocus) October 21, 2009 -- Data presented this week at the annual meeting of the Society for Neuroscience highlighted the ability of a jellyfish protein “aequorin” to protect neurons after a stroke. In prior conferences, data from the University of Wisconsin-Milwaukee demonstrated aequorin’s ability to protect cells prior to an ischemic event. Quincy Bioscience Quincy Bioscience is a partner in the research and development of the jellyfish protein as a novel therapeutic for neurodegenerative diseases.

The data presented at the prestigious conference highlights the continuing story of an unusual compound making its presence known in the field of neuroscience. “Stroke is used in the laboratory because the model replicates a biochemical process in a few minutes what neurodegeneration takes years to do and gives us a good idea of a compound’s neuroprotective ability.” explains Mark Underwood, Quincy Bioscience president.

The neuroscience pipeline for drug development has been lacking significant breakthroughs for several years. “The bar for Alzheimer’s drugs is not very high. The existing approved drugs for Alzheimer’s have provided a small amount of improvement for the lives of patients and caregivers.”

According to the calcium hypothesis of brain aging, one of the reasons for reasons for neurodegeneration is the brain cell’s inability to regulate calcium ions. Calcium binding proteins (CaBPs) are intracellular proteins that help regulate calcium. Their decline is gradual in normal aging and is believed to contribute to elevated calcium ion levels which in turn affect brain function. Conversely, in neurodegeneration, CaBP production declines rapidly and contributes to cell death.

For people over forty years of age it is estimated that 30,000 – 50,000 brain cells die each day which can lead to cognitive challenges such as an impaired ability to learn and retain new information as well as memory loss.

Aequorin is a naturally-occurring CaBP and was first discovered in glowing jellyfish in the Puget Sound by Princeton researcher Osamu Shimomura, Ph.D. in 1962. Dr. Shimomura was one of the recipients of the Nobel Prize in Chemistry 2008 for the discovery and development of this protein for the advancement in calcium research. Aequorin’s DNA structure is very similar to the CaBPs produced in the brain. Quincy Bioscience has patent-filings for the novel use of Aequorin for the purposes of neuronal calcium regulation.

ABOUT QUINCY BIOSCIENCE
Quincy Bioscience is a biotech company located in Madison, Wisconsin focused on the discovery, development and commercialization of novel medicines to treat age related memory loss and the diseases of aging. The company's therapeutic focus is on alleviating the consequences of impaired calcium homeostasis - the imbalance of calcium ions thought to be related to neurodegenerative diseases such as Alzheimer's and Parkinson's.

# # #

Read the full story at http://www.prweb.com/releases/Brain/Health/prweb3090774.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related biology technology :

1. Jellyfish Protein Shows Potential to Help With Memory
2. Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease
3. China-Biotics, Inc. Launches Shining Probiotics Protein Powder
4. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
5. When proteins, antibodies and other biological molecules kiss, a new kind of biosensor can tell
6. New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrines Anti-PS Technology Platform
7. Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio
8. Decision Biomarkers Awarded U.S. Patent for Protein Array Surface Chemistry
9. STALLERGENES and Protein eXpert Enter Into a Partnership for Producing Mites Recombinant Allergens
10. Alfacell Announces ONCONASE(R) Purchase and Supply Agreement with Scientific Protein Laboratories
11. Decision Biomarkers Launches System for Faster, Easier Quantification of Protein Biomarkers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Jellyfish Protein Extends Neuroprotective Tentacles at Neuroscience Conference
(Date:10/12/2017)... ... ... AMRI, a global contract research, development and manufacturing organization ... quality of life, will now be offering its impurity solutions as a stand-alone ... for all new drug products, including the finalization of ICH M7 earlier this ...
(Date:10/11/2017)... ... 2017 , ... Personal eye wash is a basic first aid supply for any work environment, ... eye do you rinse first if a dangerous substance enters both eyes? It’s one less ... with its unique dual eye piece. , “Whether its dirt and debris, or an acid ...
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 /PRNewswire/ ... London (ICR) and University of ... tool to risk-stratify patients with multiple myeloma (MM), in a ... . The University of Leeds is ... Myeloma UK, and ICR will perform the testing services to ...
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building ... corporate rebranding initiative announced today. The bold new look is part of a ... company moves into a significant growth period. , It will also expand its service ...
Breaking Biology Technology:
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market ... Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast ... from USD 14.30 Billion in 2017 to USD 31.75 Billion by 2022, ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ... appointment of independent Directors Mr. Robin D. Richards ... Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive ... their guidance and benefiting from their considerable expertise as we ...
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... anticipated to expand at a CAGR of 25.76% during ... diseases is the primary factor for the growth of ... report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global ... product, technology, application, and geography. The stem cell market ...
Breaking Biology News(10 mins):