Navigation Links
Jeffrey Epstein, Science Financier, Changes the Course of Evolution at Harvard

NEW YORK, June 12, 2013 /PRNewswire/ -- Ten years ago the Program for Evolutionary Dynamics was founded at Harvard with a $30 million dollar grant from a financier called Jeffrey Epstein. Since then, the Program, under the direction of Martin Nowak, a professor of Mathematics and Biology at Harvard, has changed the way in which evolution is studied and utilized.

The Program is the first to study the evolution of micro biology with the use of mathematics. It is also the first to develop mathematical models of how cancer cells evolve as well as various bacteria and viruses such as HIV. The creation of such models has led to key discoveries in combatting diseases of all kinds.

In 2012 for example, the Program developed the first mathematical model of how colon cancer cells become immune to inhibitor therapy. The research showed how the KRAS gene is not activated from inhibitor drugs, making cells resistant, but rather a small percentage of cancer cells with an inherantly activated KRAS gene are immune from the start and evolve to predominance as other cancer cells are destroyed by the inhibitor drug. The discovery was critical because instead of applying drugs in sequence to fight resistance, using a cocktail of inhibitor drugs to capture both activated KRAS gene cells and those without, came into focus.

In 2010, the Program published a study showing that most solid tumors contain 40 to 100 genetic mutations, but on average only 5 to 15 actually drive tumor growth. The findings highlighted the importance of targeting only a minority of tumor cells for effective inhibitor treatment.

"Mathematics in evolutionary biology is an exciting new field," Jeffrey Epstein remarked, whose foundation supports cutting edge science across the United States. "It reveals patterns that are otherwise hard to detect."

In addition to disease analysis, the Program has advanced critical evolutionary concepts, including "natural cooperation", quantitative analysis for the evolution of language, game theory, pre-life theory and spatial selection.

Jeffrey Epstein is the founder of the Jeffrey Epstein VI Foundation. He sits on the board for the Mind, Brain and Behavior Committee at Harvard University.

SOURCE Jeffrey Epstein VI Foundation
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Carnegie Mellons Jeffrey Hollinger Leads Research Team Developing New Tools To Ease Pain of Combat Injuries
2. A Genetic Approach For Crohns And Colitis Disease Is Financed By The Jeffrey Epstein VI Foundation
3. Synthetic Biologics Appoints Jeffrey J. Kraws as Independent Chairman
4. Stephen Epstein, MD To Head Scientific & Medical Advisory Board For Stemedica’s Cardiology Division
5. Computer Review Monitors Science and Technology Parks
6. Bayer Anniversary Tour: Hands-on Science for All
7. MEI Pharma Adds Former YM BioSciences CEO Nick Glover To Board Of Directors
8. BioDelivery Sciences Announces NDA Submission for BUNAVAIL on Track Following Positive Pre-NDA Meeting with FDA
9. Leveraging an Academic-Industry Partnership for Commercial Success, New Life Science Webinar Hosted By Xtalks
10. Endpoint Based Protocol Development: A Central Laboratory Perspective + Microbiology Case Study, New Life Science Webinar Hosted by Xtalks
11. Caris Life Sciences ASCO Presentation Highlights the Utility of Molecular Profiling for the Management of Rare and Aggressive Cancers
Post Your Comments:
(Date:11/25/2015)... 2015 The Global Genomics ... professional and in-depth study on the current state ... ) , The report ... definitions, classifications, applications and industry chain structure. The ... markets including development trends, competitive landscape analysis, and ...
(Date:11/24/2015)... 24, 2015 Halozyme Therapeutics, Inc. (NASDAQ: HALO ) ... New York on Wednesday, December 2 at 9:30 ... president and CEO, will provide a corporate overview. th ... at 1:00 p.m. ET/10:00 a.m. PT . Jim ... provide a corporate overview. --> th Annual Oppenheimer ...
(Date:11/24/2015)... 2015  Clintrax Global, Inc., a worldwide provider of clinical research ... announced that the company has set a new quarterly earnings record ... quarter growth posted for Q3 of 2014 to Q3 of 2015. ... Mexico , with the establishment of an Asia-Pacific ... United Kingdom and Mexico ...
(Date:11/24/2015)... York , November 24, 2015 ... a recent market research report released by Transparency Market ... to expand at a CAGR of 17.5% during the ... Prenatal Testing Market - Global Industry Analysis, Size, Volume, ... the global non-invasive prenatal testing market to reach a ...
Breaking Biology Technology:
(Date:10/26/2015)... Calif. , Oct. 26, 2015  Delta ID ... biometric authentication to mobile and PC devices, announced its ... smartphone, the arrows NX F-02H launched by NTT DOCOMO, ... NX F-02H is the second smartphone to include iris ... technology in ARROWS NX F-04G in May 2015, world,s ...
(Date:10/23/2015)... and GOLETA, California , ... HFES conference, BIOPAC and SensoMotoric Instruments (SMI) announce a ... eye tracking data captured during interactive real-world tasks ... and play integration of their established wearable solutions for ... to synchronize gaze behavior captured with SMI Eye ...
(Date:10/22/2015)... Calif., Oct. 22, 2015  Synaptics (NASDAQ: SYNA ), a ... its first quarter ended September 30, 2015. ... of fiscal 2016 grew 66 percent over the comparable quarter last ... fiscal 2016 was $23.8 million, or $0.62 per diluted share. ... for the first quarter of fiscal 2016 grew 39 percent over ...
Breaking Biology News(10 mins):