Navigation Links
Jeffrey Epstein, Science Financier, Changes the Course of Evolution at Harvard
Date:6/12/2013

NEW YORK, June 12, 2013 /PRNewswire/ -- Ten years ago the Program for Evolutionary Dynamics was founded at Harvard with a $30 million dollar grant from a financier called Jeffrey Epstein. Since then, the Program, under the direction of Martin Nowak, a professor of Mathematics and Biology at Harvard, has changed the way in which evolution is studied and utilized.

The Program is the first to study the evolution of micro biology with the use of mathematics. It is also the first to develop mathematical models of how cancer cells evolve as well as various bacteria and viruses such as HIV. The creation of such models has led to key discoveries in combatting diseases of all kinds.

In 2012 for example, the Program developed the first mathematical model of how colon cancer cells become immune to inhibitor therapy. The research showed how the KRAS gene is not activated from inhibitor drugs, making cells resistant, but rather a small percentage of cancer cells with an inherantly activated KRAS gene are immune from the start and evolve to predominance as other cancer cells are destroyed by the inhibitor drug. The discovery was critical because instead of applying drugs in sequence to fight resistance, using a cocktail of inhibitor drugs to capture both activated KRAS gene cells and those without, came into focus.

In 2010, the Program published a study showing that most solid tumors contain 40 to 100 genetic mutations, but on average only 5 to 15 actually drive tumor growth. The findings highlighted the importance of targeting only a minority of tumor cells for effective inhibitor treatment.

"Mathematics in evolutionary biology is an exciting new field," Jeffrey Epstein remarked, whose foundation supports cutting edge science across the United States. "It reveals patterns that are otherwise hard to detect."

In addition to disease analysis, the Program has advanced critical evolutionary concepts, including "natural cooperation", quantitative analysis for the evolution of language, game theory, pre-life theory and spatial selection.

Jeffrey Epstein is the founder of the Jeffrey Epstein VI Foundation. He sits on the board for the Mind, Brain and Behavior Committee at Harvard University.

http://www.jeffreyepstein.org


'/>"/>
SOURCE Jeffrey Epstein VI Foundation
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Carnegie Mellons Jeffrey Hollinger Leads Research Team Developing New Tools To Ease Pain of Combat Injuries
2. A Genetic Approach For Crohns And Colitis Disease Is Financed By The Jeffrey Epstein VI Foundation
3. Synthetic Biologics Appoints Jeffrey J. Kraws as Independent Chairman
4. Stephen Epstein, MD To Head Scientific & Medical Advisory Board For Stemedica’s Cardiology Division
5. Computer Review Monitors Science and Technology Parks
6. Bayer Anniversary Tour: Hands-on Science for All
7. MEI Pharma Adds Former YM BioSciences CEO Nick Glover To Board Of Directors
8. BioDelivery Sciences Announces NDA Submission for BUNAVAIL on Track Following Positive Pre-NDA Meeting with FDA
9. Leveraging an Academic-Industry Partnership for Commercial Success, New Life Science Webinar Hosted By Xtalks
10. Endpoint Based Protocol Development: A Central Laboratory Perspective + Microbiology Case Study, New Life Science Webinar Hosted by Xtalks
11. Caris Life Sciences ASCO Presentation Highlights the Utility of Molecular Profiling for the Management of Rare and Aggressive Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... April 29, 2016 Elekta is ... update to its industry-leading treatment planning software, is available ... Monaco version 5.11 provides significant performance ... calculation speeds up to four times faster than in ... the industry,s gold standard Monte Carlo ...
(Date:4/28/2016)... New York, NY (PRWEB) , ... April 28, ... ... plan, QuickSTAT has made significant investments in recruiting top industry experts, and expanding ... IT Platform, which provides industry-leading tools for clients to manage their clinical trial ...
(Date:4/27/2016)... ... April 27, 2016 , ... ... screen mobile devices with fingerprint recognition for secure access, voice recognition for hands-free ... few ways consumers are interacting with biometrics technology today. But if they ...
(Date:4/27/2016)... ... April 27, 2016 , ... ... to its Scientific Advisory Board. Dr. Lamka will assist PathSensors in expanding the ... , PathSensors deploys the CANARY® test platform for the detection of harmful ...
Breaking Biology Technology:
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
(Date:4/13/2016)... April 13, 2016  IMPOWER physicians supporting Medicaid patients ... a new clinical standard in telehealth thanks to a ... the higi platform, IMPOWER patients can routinely track key ... body mass index, and, when they opt in, share ... visit to a local retail location at no cost. ...
(Date:3/22/2016)... PUNE, India , March 22, 2016 ... new market research report "Electronic Sensors Market for ... Fingerprint, Proximity, & Others), Application (Communication & ... and Geography - Global Forecast to 2022", ... consumer industry is expected to reach USD ...
Breaking Biology News(10 mins):