Navigation Links
Jeffrey Epstein, Science Financier, Changes the Course of Evolution at Harvard

NEW YORK, June 12, 2013 /PRNewswire/ -- Ten years ago the Program for Evolutionary Dynamics was founded at Harvard with a $30 million dollar grant from a financier called Jeffrey Epstein. Since then, the Program, under the direction of Martin Nowak, a professor of Mathematics and Biology at Harvard, has changed the way in which evolution is studied and utilized.

The Program is the first to study the evolution of micro biology with the use of mathematics. It is also the first to develop mathematical models of how cancer cells evolve as well as various bacteria and viruses such as HIV. The creation of such models has led to key discoveries in combatting diseases of all kinds.

In 2012 for example, the Program developed the first mathematical model of how colon cancer cells become immune to inhibitor therapy. The research showed how the KRAS gene is not activated from inhibitor drugs, making cells resistant, but rather a small percentage of cancer cells with an inherantly activated KRAS gene are immune from the start and evolve to predominance as other cancer cells are destroyed by the inhibitor drug. The discovery was critical because instead of applying drugs in sequence to fight resistance, using a cocktail of inhibitor drugs to capture both activated KRAS gene cells and those without, came into focus.

In 2010, the Program published a study showing that most solid tumors contain 40 to 100 genetic mutations, but on average only 5 to 15 actually drive tumor growth. The findings highlighted the importance of targeting only a minority of tumor cells for effective inhibitor treatment.

"Mathematics in evolutionary biology is an exciting new field," Jeffrey Epstein remarked, whose foundation supports cutting edge science across the United States. "It reveals patterns that are otherwise hard to detect."

In addition to disease analysis, the Program has advanced critical evolutionary concepts, including "natural cooperation", quantitative analysis for the evolution of language, game theory, pre-life theory and spatial selection.

Jeffrey Epstein is the founder of the Jeffrey Epstein VI Foundation. He sits on the board for the Mind, Brain and Behavior Committee at Harvard University.

SOURCE Jeffrey Epstein VI Foundation
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Carnegie Mellons Jeffrey Hollinger Leads Research Team Developing New Tools To Ease Pain of Combat Injuries
2. A Genetic Approach For Crohns And Colitis Disease Is Financed By The Jeffrey Epstein VI Foundation
3. Synthetic Biologics Appoints Jeffrey J. Kraws as Independent Chairman
4. Stephen Epstein, MD To Head Scientific & Medical Advisory Board For Stemedica’s Cardiology Division
5. Computer Review Monitors Science and Technology Parks
6. Bayer Anniversary Tour: Hands-on Science for All
7. MEI Pharma Adds Former YM BioSciences CEO Nick Glover To Board Of Directors
8. BioDelivery Sciences Announces NDA Submission for BUNAVAIL on Track Following Positive Pre-NDA Meeting with FDA
9. Leveraging an Academic-Industry Partnership for Commercial Success, New Life Science Webinar Hosted By Xtalks
10. Endpoint Based Protocol Development: A Central Laboratory Perspective + Microbiology Case Study, New Life Science Webinar Hosted by Xtalks
11. Caris Life Sciences ASCO Presentation Highlights the Utility of Molecular Profiling for the Management of Rare and Aggressive Cancers
Post Your Comments:
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
(Date:6/23/2016)... , June 23, 2016 On Wednesday, ... at 4,833.32, down 0.22%; the Dow Jones Industrial Average edged ... closed at 2,085.45, down 0.17%. has initiated coverage on ... ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals ... (NASDAQ: BIND ). Learn more about these stocks ...
Breaking Biology Technology:
(Date:5/12/2016)... May 12, 2016 , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 /PRNewswire/ ... product subsidiary of Infosys (NYSE: INFY ), and ... global partnership that will provide end customers with ... banking and payment services.      (Logo: ... area for financial services, but it also plays a fundamental ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
Breaking Biology News(10 mins):