James L. Wittliff, Ph.D., FACB, to Present 'Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System' at the Association for Molecular Pathology Conference, October 30
ding to Dr. Wittliff Advantages of the Ziplex automated systemto ou...Dr. Wittliff was among the first investigators to prove that theexpre...About Xceed Molecular A HREF http://www.XceedMolecular.com target ...
Date:10/28/2008
ding to Dr. Wittliff, "Advantages of the Ziplex automated system
to our research include retention of tissue biopsy custody and the rapid,
reproducible analyses of gene subsets to investigate breast cancer behavior
in order to identify clinically relevant molecular signatures."
Dr. Wittliff was among the first investigators to prove that the
expression of estrogen receptors in breast cancer predicted a patient's
response to hormone therapy. This finding led to collaborations with the
National Surgical Adjuvant Breast Project (NSABP), establishing Tamoxifen
as adjuvant therapy for breast cancer and use of receptor proteins as
tissue biomarkers of a patient's prognosis and response. With NEN/Dupont,
Dr. Wittliff developed the original FDA-approved kits for assessing
receptors in biopsies. His laboratory was designated the National Reference
Facility for performing quality assurance (QA) surveys of receptor testing
for historical clinical trials in North America and for establishing the
College of American Pathologists QA Surveys. In recognition of his
contributions to medicine, the University of Innsbruck, Austria, awarded
Dr. Wittliff, Doctor of Medicine honoris causa. The American Association
for Clinical Chemistry honored him with an award for Outstanding
Contributions to Clinical Chemistry in a Selected Area of Research; he is
also the recipient of the Distinguished Scientist's Award by the Clinical
Ligand Assay Society. In 2004, the American Cancer Society recognized his
lifetime achievements with the Goldsmith Research Excellence Award. His
research team is now working with Xceed to develop clinically related tests
for breast and other cancers using its proprietary Ziplex System. Dr.
Wittliff's discoveries and development of a unique tumor marker database
resulted in the filing of new patents for the University of Louisville and
the licensing of his technologies.
About Xceed Molecular (http://ww
'/>"/>
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