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JDRF and California Institute for Regenerative Medicine Increase Funding of ViaCyte
Date:2/13/2013

y ViaCyte is very promising," said Julia Greenstein , Ph.D., JDRF's  vice president of cure therapies. "The ability to encapsulate and thereby protect implanted insulin-producing cells has been a focus for JDRF because of its potential to solve multiple problems at once. ViaCyte is currently at the forefront of developing this technology, making this a very attractive research opportunity for us."

The contributions by JDRF and CIRM are intended to move ViaCyte's combination of stem cell-derived pancreatic progenitors and encapsulation device (VC-01 combination product) to approval by the U.S. Food and Drug Administration (FDA) for proof of concept human clinical trials. To date, VC-01 has been shown to be effective in controlling blood glucose in multiple preclinical models, and clinical trials to initially investigate the safety and efficacy in patients with T1D are expected to be initiated next year.

Dr. Paul Laikind , ViaCyte's chief executive officer and president, said, "CIRM and JDRF are valuable partners as we pursue this potentially transformative new approach to controlling insulin-dependent diabetes. While we appreciate their financial awards, we have also benefited from the valuable technical support and advocacy they provide to our program. With their help we will soon determine if the promising results we have demonstrated in preclinical studies translate to patients. If so, VC-01 could essentially represent a cure for type 1 diabetes and an important therapy for patients with insulin-requiring type 2 diabetes."

Video Link
ViaCyte's research and development of a cell encapsulation product holds the promise of a cure for people with T1D and their families. This CIRM produced video describes the work bei
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SOURCE JDRF
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