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JCI table of contents: April 22, 2008

L-11, generating an amplification effect. The importance of these observations is discussed in detail in an accompanying commentary by Juanita Merchant, at the University of Michigan, Ann Arbor.

TITLE: STAT3 and STAT1 mediate IL-11dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Matthias Ernst
Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Phone: 61-3-9341-3155; Fax: 61-3-9341-3104; E-mail:

Brendan J. Jenkins
Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia.
Phone: 61-3-9594-7218; Fax: 61-3-9594-7211; E-mail:

View the PDF of this article at:

TITLE: What lurks beneath: IL-11, via Stat3, promotes inflammation-associated gastric tumorigenesis

Juanita L. Merchant
University of Michigan, Ann Arbor, Michigan, USA.
Phone: (734) 647-2944; Fax: (734) 763-4686; E-mail:

View the PDF of this article at:

NEPHROLOGY: Connecting the dots between obesity and kidney disease

Individuals who are obese have a greater risk of developing kidney disease than those who are not obese. New data, generated by a team of researchers at the University of California at San Diego, La Jolla, and Jefferson Medical College, Philadelphia, have outlined a mechanism by which obesity can cause a clinical condition that is an indicator of kidney dama

Contact: Karen Honey
Journal of Clinical Investigation

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