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IsoTis Files Definitive Proxy Statement
Date:9/5/2007

Special Stockholders Meeting to Approve Merger With Integra on October 11,

2007

IRVINE, California, September 5 /PRNewswire-FirstCall/ -- IsoTis, Inc. (NASDAQ: ISOT) ("IsoTis"), an orthobiologics company, today announced the filing of a definitive proxy statement with the U.S. Securities and Exchange Commission ("SEC") in connection with the IsoTis-Integra LifeSciences Holdings Corporation (NASDAQ: IART) ("Integra") combination. The proxy statement is available on the investor portion of the company's corporate website, and was first mailed to stockholders on or about September 5, 2007.

The Proxy Statement relates to a special meeting of stockholders of IsoTis to be held on October 11, 2007 in Irvine, CA,, at which IsoTis' stockholders will be asked to approve the acquisition of IsoTis by Integra pursuant to an agreement and plan of merger dated as of August 6, 2007. If the acquisition is consummated, stockholders will be entitled to receive $7.25 in cash, without interest, for each share of IsoTis common stock that they own.

IsoTis will also distribute to its stockholders a separate document that highlights certain important components of the proxy statement and translates these components into Dutch, French and German. These highlights and translations will be mailed to stockholders and are made available on the investor portion of the company's corporate website.

In addition, in advance of the October 11, 2007 stoc
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SOURCE IsoTis Inc
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