Navigation Links
IsoPlexis Obtains Exclusive License to Breakthrough Single-Cell Metabolomics Analysis Technologies From Dr. James Heath’s Lab at Caltech
Date:3/27/2017

IsoPlexis Corporation (IsoPlexis), a venture capital-funded life sciences company dedicated to accelerating the fight against cancer, autoimmune disease and more through a single-cell precision engineering platform, today announced it has received an exclusive license to the single-cell metabolomics and proteomics analysis platform developed in the laboratory of Dr. James Heath at the California Institute of Technology, a pioneer in applying chemical physics to biological problems.

Dr. James Heath’s new inventions enable detection of multiple types of metabolite information from single cells, a capability that aligns well with the IsoCode technology, previously referred to as the SCBC (single-cell barcode chip) solution and the foundation of IsoPlexis’ technologies.

The metabolomics analysis platform provides the ability to track novel metabolite biomarkers involved in the progression of various cancers. The technology’s ability to monitor glioblastoma progression has been detailed in peer-reviewed journals, such as the Journal of the American Chemical Society (JACS).

Sean Mackay, IsoPlexis’ Chief Executive Officer, said, “Dr. Heath’s metabolomics innovations provide yet another critical source of novel information to help clinicians understand the progression of cancer in subsets of cells. Working with a pioneering technical institution like Caltech and developing these highly precise detection solutions with Dr. Heath is just one example of how we’re working to accelerate the fight against cancer.”

Dr. James Heath, Elizabeth W. Gilloon Professor of Chemistry at Caltech, was named one of the seven most powerful innovators of the world by Forbes magazine in 2009. Previously, he founded the California NanoSystems Institute at UCLA and was awarded the prestigious Feynman Prize in Nanotechnology as the co-architect of the first quantum-based, molecular computer switch.

More recently, Dr. Heath has applied his expertise in chemical physics and nanotechnologies to advancing the field of translational medicine, with a specific focus on detecting early stages of resistance in cancers and harnessing the power of the immune system to fight cancer. His breakthrough single-cell analysis platform advances the rapidly growing field of metabolomics, which is seen as critical to developing personalized oncology treatments and monitoring cancer progression. Dr. Heath also sits on the IsoPlexis Board of Directors and Scientific Advisory Board.

Dr. James Heath said, “Several metabolic processes are highly elevated during many transitions from health to disease, and some metabolic signals can even play roles in suppressing anti-cancer immune responses. However, metabolites are small molecules and, unlike proteins, aren’t easily connected to the genetic code. The ability to monitor both metabolites and proteins from the same single cells allows us to begin establishing such connections. Adding additional engineering innovation to the IsoCode technology uniquely positions IsoPlexis to help advance precision medicine, and I am excited we are working together to address some of today’s toughest problems.”

ABOUT ISOPLEXIS:
IsoPlexis is a life sciences company committed to advancing groundbreaking research and therapeutic development in immunology, oncology and other emerging disease areas. The IsoPlexis cellular response analysis platform was developed by scientific leaders at Yale and Caltech. By isolating single immune cells and analyzing their functional omic response, the platform can assess safety and efficacy of therapeutics and monitor disease progression, enabling improved therapeutic development and patient outcomes. Through collaborations with leading pharmaceutical companies and academic labs, the IsoPlexis technology is improving the targeting of breakthrough treatments. The venture capital-funded Yale spinout is headquartered in Branford, Connecticut. For additional information on IsoPlexis, visit http://www.isoplexis.com or email info(at)isoplexis(dot)com.

Read the full story at http://www.prweb.com/releases/2017/03/prweb14187610.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related biology technology :

1. IsoPlexis Awarded NIH SBIR Grant to Develop Cellular Analysis Platform to Diagnose and Monitor Alzheimer’s
2. GraftWorx Obtains a Pioneer of Sensor Technology and a Key Leader in MEMS
3. Sinovac Obtains Clinical Trial Approval for Sabin-IPV Candidate
4. DS Biopharma Obtains a Granted Patent Covering the Use of DS102 to Treat Fatty Liver Disorders
5. Kultevat obtains license of gene switch technology
6. Avexegen Therapeutics Announces Exclusive License Agreement with Children’s Hospital Los Angeles
7. ThermaGenix, Inc. Announces Start-up and Exclusive Licenses from Brandeis University
8. Immunomedics Enters into Exclusive Global Licensing Agreement with Seattle Genetics for Sacituzumab Govitecan (IMMU-132) with Potential Payments of up to Approximately $2 Billion, Plus Royalties
9. Collective Medical Technologies Edie (a.k.a. PreManage ED) Solution is Exclusively Endorsed by the American College of Emergency Physicians
10. AxioMed Announces 15-year Exclusive Worldwide License on Proprietary Viscoelastic Material with the patent holder DSM
11. Pillar Clinical Research Selects Verified Clinical Trials As Exclusive Provider To Reduce Professional Subjects From Duplicate Enrollment In Their Clinical Trials.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2017)... CA (PRWEB) , ... May 19, 2017 , ... ... annual meeting and educational conference of the American Association of Bioanalysts (AAB) and ... Galleria Hotel in Houston. The conference reinforces AAB’s commitment to excellence in clinical ...
(Date:5/18/2017)... (PRWEB) , ... May 18, 2017 , ... ... procedure on April 28, 2017 at the Prince Of Wales Private Hospital. The ... disc at level C6-C7. The patient failed conservative treatments prior to undergoing surgery. ...
(Date:5/18/2017)... ... May 17, 2017 , ... ... expertise, and further enhances its scientific power by providing investigators access to ... has agreed to join the scientific advisory board. “We are committed to ...
(Date:5/18/2017)... ... 17, 2017 , ... G-CON Manufacturing, Inc., the leader in ... Jornitz, was recognized as a Top 10 Industry Influencer on The Medicine Maker’s ... bettering the pharma industry and bringing life-changing medicines to market” across four categories. ...
Breaking Biology Technology:
(Date:3/22/2017)... 2017 Optimove , provider of ... such as 1-800-Flowers and AdoreMe, today announced two ... Replenishment. Using Optimove,s machine learning algorithms, these features ... replenishment recommendations to their customers based not just ... customer intent drawn from a complex web of ...
(Date:3/20/2017)... At this year,s CeBIT Chancellor Dr. Angela Merkel visited ... to the DERMALOG stand together with the Japanese Prime Minster Shinzo Abe. ... the largest German biometrics company the two government leaders could see the ... well as DERMALOG´s multi-biometrics system.   Continue Reading ... ...
(Date:3/16/2017)... CeBIT 2017 - Against identity fraud with DERMALOG solutions "Made in ... ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity fraud. ... Used combined in one project, multi-biometric solutions ... ...
Breaking Biology News(10 mins):