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Isis Reports Financial Results and Highlights for Second Quarter of 2008

pro forma income (loss) from operations were adjusted from GAAP to exclude compensation expense related to stock options, which are non-cash. Isis has regularly reported non-GAAP measures for operating expenses and loss from operations as pro forma results. These measures are provided as supplementary information and are not a substitute for financial measures calculated in accordance with GAAP. Isis reports these pro forma results to better enable financial statement users to assess and compare its historical performance and project its future operating results and cash flows. Further, the presentation of Isis' pro forma results is consistent with how Isis' management internally evaluates the performance of its operations.

Ibis Biosciences, Inc.

Statements of Operations

(In Thousands)

Three months ended, Six months ended,

June 30, June 30,

2008 2007 2008 2007

(unaudited) (unaudited)


Commercial revenue(1) $1,098 $810 $2,293 $1,441

Research and development

revenue under collaborative

agreements 2,160 1,081 3,944 2,026

Total revenue 3,258 1,891 6,237 3,467


Cost of commercial revenue(2) 3,078 1,266 3,895 2,801

Research and development 3,572 2,460 8,128 4,647

Selling, general and

administrative 2,024 1,035 3,527 2,023

Total operating expenses 8,674 4,761 15,550 9,471

Loss from operations $(5,416) $(2,870) $(9,313) $(6,004)

(1) Ibis' commerci

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

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