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Isis Pharmaceuticals and Thomas, McNerney & Partners Announce That the Newly Formed Altair Therapeutics Will Develop Antisense Drugs for Respiratory Conditions
Date:10/16/2007

antisense drugs for the treatment of asthma and other respiratory conditions. More information on Altair is available at http://www.altairtherapeutics.com.

About ISIS 369645

ISIS 369645 is an antisense drug that acts as an inhibitor of the IL-4/IL-13 cytokine signaling pathways, which play an important role in asthma. In preclinical studies, inhibition of IL-4/IL-13 signaling pathways reduced lung cytokine production, inflammation, and airway hyper-responsiveness and when delivered by inhalation can rapidly distribute to target tissues at therapeutic doses.

About Thomas, McNerney & Partners

Thomas, McNerney & Partners, LLC, is a health care private equity firm that invests in life science and medical technology companies. Employing a multi-stage investment approach, Thomas, McNerney & Partners has just under $600 million in assets under management and provides seed and early stage funding to help entrepreneurs launch companies, as well as growth capital to emerging companies for furthering clinical development or for expansion of product commercialization. For more information, please visit http://www.tm-partners.com .

ABOUT ISIS PHARMACEUTICALS, INC.

Isis is exploiting its expertise in RNA to discover and develop novel drugs for its product pipeline and for its partners. The Company has successfully commercialized the world's first antisense drug and has 17 drugs in development. Isis' drug development programs are focused on treating cardiovascular and metabolic diseases. Isis' partners are developing drugs for a wide variety of diseases. Ibis Biosciences, Inc., Isis' wholly owned subsidiary, is developing and commercializing the Ibis T5000(TM) Biosensor System, a revolutionary system to identify infectious organisms. As an innovator in RNA-based drug discovery and development, Isis is the owner or exclusive licens
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SOURCE Isis Pharmaceuticals, Inc.
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