Navigation Links
Isis Enters Broad Collaboration With Ortho-McNeil, Inc. for the Discovery, Development and Commercialization of Antisense Drugs to Treat Metabolic Diseases
Date:9/13/2007

- Includes license of two antisense drugs in development targeting glucagon

receptor and glucocorticoid receptor - Includes research collaboration to identify antisense drugs to inhibit

additional targets to treat metabolic diseases

- Conference call webcast Thursday, September 13, 9:45 a.m. EDT at

http://www.isispharm.com

CARLSBAD, Calif., Sept. 13 /PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) today announced a broad collaboration with Ortho-McNeil, Inc., a Johnson & Johnson company, to discover, develop and commercialize antisense drugs to treat metabolic diseases, including Type 2 diabetes. As part of the collaboration, Isis will grant to Ortho-McNeil worldwide development and commercialization rights to two of its diabetes development candidates, ISIS 325568 and ISIS 377131, which selectively inhibit the production of glucagon receptor (GCGR) and glucocorticoid receptor (GCCR), respectively. Additionally, Ortho-McNeil will provide funding to Isis to support the joint discovery of novel drugs to treat metabolic diseases, including diabetes and obesity. After the initial collaboration phase, Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD) will continue development of these drugs.

Ortho-McNeil will pay Isis a $45 million upfront licensing fee, and will provide Isis with research and development funding over the period of the collaboration. In addition to the licensing fee, Isis could receive over $230 million in milestone payments upon successful development and regulatory approvals of ISIS 325568 and ISIS 377131, as well as royalties
'/>"/>

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. WARF enters licensing agreements for stem cell products
2. Virent enters agreement with Shell Oil unit to make hydrogen with biomass
3. Software company enters health space with RFID solutions on hold
4. Lucigen Corp. enters global licensing agreement
5. Call centers and customer service: The good, the bad, and the clueless
6. GE Healthcare enters agreement with Canadian health authority
7. Data centers: Buyers beware of over-hyped facilities
8. Data centers: Blowing smoke and raising red flags
9. Prodesse enters patent agreement with Roche
10. UW-Madison enters Kauffman grant competition
11. Applied Technology Centers to aid printing and manufacturing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... 2015  Twelve patients today are preparing to participate ... at California Pacific Medical Center (CPMC), a Sutter Health ... will be the largest single-center kidney paired donation chain ... in the 44-year history of the CPMC Transplant Center. ... an altruistic donor who did not have a specific ...
(Date:3/5/2015)... Buffalo, New York (PRWEB) March 05, 2015 ... want veterans to be able to get an Advanced ... Time, money, stress, blaming and guessing are all risk ... with assuming the woman is the source of the ... and female. LifeCell Dx has the simplest, least ...
(Date:3/5/2015)... BioPlus Specialty Pharmacy (BioPlus) announces the hiring ... of Managed Care. In this role, Damm will build ... nation’s leading specialty pharmacies. , Damm, who is based ... pharmacy and biotech experience to his new position with ... and Pfizer. Prior to working in Healthcare Damm served ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 North ... Pierre Noel, M.D., Professor of Medicine, Mayo Clinic ... Company’s Board of Directors. , Entegrion’s ... extremely fortunate to have Dr. Noel, a distinguished ... healthcare organization, join Entegrion’s Board. His expertise in ...
Breaking Biology Technology:Altruistic donor starts large West Coast single-center kidney paired donation at CPMC 2Altruistic donor starts large West Coast single-center kidney paired donation at CPMC 3Altruistic donor starts large West Coast single-center kidney paired donation at CPMC 4LifeCell Dx Offers New Option to Veterans with Infertility 2LifeCell Dx Offers New Option to Veterans with Infertility 3BioPlus Specialty Pharmacy Announces Hiring of New Vice President of Managed Care: Jamie Damm 2Entegrion Announces Appointment of Pierre Noel, MD, to Its Board of Directors 2
... MaxCyte, Inc., a,clinical-stage therapeutics company and pioneer ... that Anthony Recupero, Ph.D.,Vice President Business Development ... 2008, at 2:00PM at the BIO-Europe Spring ... will discuss the development of,engineered cell based ...
... continues to advance collaborative research worldwide, ... Biosystems, Inc.,announced today that leading research institutions, ... at the University of,Queensland, and the Biotech ... University of Copenhagen have recently purchased access ...
... 2008 /Xinhua-PRNewswire-FirstCall/ -- China YCT,International Group Inc. (OTC ... subsidiary, Shandong Spring Pharmaceutical Co., Ltd, has,entered into ... Tang,Bioengineering Co. Ltd., effective as of April 4, ... manage the operations of,Shandong Yong Chun Tang, in ...
Cached Biology Technology:Open Biosystems' Open Access RNAi Program Adopted by University of Copenhagen and University of Queensland 2Open Biosystems' Open Access RNAi Program Adopted by University of Copenhagen and University of Queensland 3China YCT International Group, Inc. Announces Entrusted Management Agreement With Its Primary Supplier 2China YCT International Group, Inc. Announces Entrusted Management Agreement With Its Primary Supplier 3
(Date:2/5/2015)... Calif. , Jan. 27, 2015 /PRNewswire/ ... provider of globally deployed, innovative test solutions ... announced the delivery of its TS-323 ... Space Systems Company (LMSSC). GENASYS is a ... demands of mission-critical applications that require performance ...
(Date:2/5/2015)... MOUNTAIN VIEW, Calif. , Feb. 3, 2015 ... screen printer technology, demand from industries such as ... the global market for surface mount technology (SMT) ... manual equipment to automatic control will push the ... glue dispensers will remain steady as glue dispensers ...
(Date:1/22/2015)... Technology Showcase, Hall E -   EyeLock Inc. , ... it will showcase its EyeLock ID technology integrated in a ... Energy,s Oak Ridge National Laboratory (ORNL) at the ... identity authentication technology is being used to validate the driver ...
Breaking Biology News(10 mins):Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3
... Scientists trying to understand why oaks are starting to ... just below the surface to find some answers. ... small rodents that live underground, prefer oak roots to ... the rodents as a possible factor leading to high ...
... 2009 As we move more toward renewable energy, questions ... If so, are humans or natural variations in climate ... research and atmospheric science will address such questions during a ... His talk is free and open to the public. ...
... Zoo post-doctoral researcher Carson Murray, Ph.D. has received a ... world,s foremost medical research centers, the National Institutes of ... Rachel Santymire, Ph.D. of Lincoln Park Zoo and Martha ... to identify stressors of wild female chimpanzees and discover ...
Cached Biology News:Danger lurks underground for oak seedlings 2Prominent climate researcher to speak at UH on global warming March 5 2Lincoln Park Zoo scientists awarded National Institutes of Health grant 2