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Investigational Diabetes Drug May Also Have Future As Treatment for Parkinson's Disease
Date:9/19/2013

insulin sensitizers, which are PPARg agonists. In a recently completed Phase 2a trial in 29 patients with dementia due to Alzheimer's disease (NCT01374438), MSDC-0160 was shown to maintain or increase glucose metabolism in the brain, as measured by FDG-PET imaging, in predefined regions of interest in the brain associated with cognitive decline.

Mitochondria and Parkinson's Disease
Parkinson's disease is a chronic, degenerative neurological disorder that affects an estimated one million people in the United States, and more than five million worldwide. Impaired mitochondrial function has been implicated in the development of Parkinson's disease. Mitochondria are the "power plants" of the cell, generating energy needed for cell activity. Therapies that improve mitochondrial function may have the potential to slow the progression of the disease.

About Metabolic Solutions Development Company
Metabolic Solutions Development Company (www.msdrx.com) is a drug discovery and development company investigating novel molecular targets and developing new therapeutics to treat metabolic diseases associated with age-related mitochondrial dysfunction, especially type 2 diabetes.

About Van Andel Institute
Established by Jay and Betty Van Andel in 1996, Van Andel Institute is an independent research organization dedicated to preserving, enhancing and expanding the frontiers of medical science, and to achieving excellence in education by probing fundamental issues of education and the learning process. This is accomplished through the work of over 200 researchers in more than 20 on-site laboratories and in collaborative partnerships that span the globe. Find out more about Van Andel Institute or donate by visiting www.vai.org

About Patrik Brun
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SOURCE Metabolic Solutions Development Company, LLC
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