Navigation Links
Intradigm Receives Notice of Allowance for Key RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

Issuance Will Give Company Patents in Each of the Three Critical Areas of RNAi Therapeutic Development

PALO ALTO, Calif., March 17 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeutics, today announced that the United States Patent and Trademark Office (USPTO) has issued the company a notice of allowance for a patent covering various aspects of a potent small interfering RNA (siRNA) sequence. The allowed subject matter covers a specific double-stranded siRNA sequence that is directed against the angiogenic pathway and which possesses therapeutic potential in the treatment of cancer. This notice of allowance pertains to the first of a number of pending patent applications covering proprietary Intradigm siRNA sequences against more than 50 clinically relevant targets.

As the first sequence-specific patent for which Intradigm has received a notice of allowance, this development supplements the company's existing patents, giving Intradigm allowed intellectual property (IP) covering each of the three critical areas for RNAi therapeutic development: target sequences, delivery and structural features. This breadth of intellectual property places Intradigm in a uniquely strong position within the RNAi therapeutic industry, especially among other private companies in the space.

"The receipt of this notice of allowance provides us a great deal of confidence in our ability to successfully prosecute our large number of pending sequence patents and, in turn, build one of the industry's strongest siRNA sequence patent positions," said Philip Haworth, chief executive officer of Intradigm. "Additionally, once this patent issues, Intradigm will possess issued patents related to siRNA sequences, siRNA delivery technology and siRNA structural motifs. We believe this breadth of coverage provides the company with a key competitive advantage in the RNAi therapeutics space."


Intradigm is a private biotechnology company committed to the discovery, development and delivery of targeted, systemic RNA interference (RNAi) therapeutics for the treatment of serious diseases with an initial focus on oncology. Intradigm is unique among private companies, with its comprehensive RNAi therapeutics platform consisting of structural features for next-generation RNAi molecules, biodegradable polycationic polymers for the delivery of RNAi therapeutics and proprietary siRNA sequence applications. Our proprietary delivery technology is unique in its potential to offer safe and effective systemic administration using a library of novel peptide-based biodegradable polymers.

We have established an impressive proprietary portfolio of siRNA sequences against more than 50 highly valued oncology and other disease targets. In addition, we have secured an exclusive license to the Zamore patent family from the University of Massachusetts, which covers broad structural features of siRNA design for more potent next-generation siRNA sequences. Our goal is to grow Intradigm to become a leading company in enabling the development of novel RNAi therapeutics against a broad range of therapeutic targets using our siRNA sequences and delivery technology.

For more information on Intradigm, please visit

SOURCE Intradigm Corporation
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Intradigm Closes Final Tranche of $21.4 Million Series B Financing
2. Intradigm Announces Issuance of Key Patent Related to Enhancing Efficacy and Potency of RNAi Therapeutics
3. Intradigm Licenses Key Next Generation RNA Interference (RNAi) Intellectual Property From University of Massachusetts Medical School
4. Helix BioPharma Receives Approval to Initiate Phase II Pharmacokinetic Clinical Study of Topical Interferon Alpha-2b in Patients with Low-Grade Cervical Lesions
5. Prometheus Receives New York State Approval for PROMETHEUS(R) IBS Diagnostic, First Blood Test for Irritable Bowel Syndrome
6. Catilin Receives Renewable Energy Award for Pilot Plant
7. Avon Protection Systems Receives NIOSH Approval for ST53 SCBA System
8. S*BIO Receives BioSpectrum Editors Choice, Emerging BioScience Company of Singapore Award
9. 3SBio Inc. Receives Official Recognition as a High-Tech Enterprise
10. AMPAC Fine Chemicals Receives the California Pollution Prevention Challenge Award Two Consecutive Years
11. Sinovac Receives GMP Certification for its New Filling and Packaging Production Facility
Post Your Comments:
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network ... Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is ... projects are designed, built and brought to market. , The Design Lab is ...
(Date:6/23/2016)... June 23, 2016  Blueprint Bio, a company dedicated ... the medical community, has closed its Series A funding ... . "We have received a commitment from ... we need to meet our current goals," stated ... the runway to complete validation on the current projects ...
Breaking Biology Technology:
(Date:6/22/2016)... 22, 2016  The American College of Medical Genetics and ... Magazine as one of the fastest-growing trade shows during ... the Bellagio in Las Vegas . ... of growth in each of the following categories: net square ... number of attendees. The 2015 ACMG Annual Meeting was ranked ...
(Date:6/21/2016)... , June 21, 2016 NuData ... the new role of principal product architect and ... the director of customer development. Both will report ... technical officer. The moves reflect NuData,s strategic growth ... response to high customer demand and customer focus ...
(Date:6/15/2016)... York , June 15, 2016 ... new market report titled "Gesture Recognition Market by Application ... Forecast, 2016 - 2024". According to the report, the  ... 11.60 billion in 2015 and is estimated to ... USD 48.56 billion by 2024.  Increasing ...
Breaking Biology News(10 mins):