Navigation Links
Intestinal flora determines health of obese people
Date:8/28/2013

The international consortium MetaHIT, which includes the research group of Jeroen Raes (VIB / Vrije Universiteit Brussel), publishes in the leading journal Nature that there is a link between richness of bacterial species in the intestines and the susceptibility for medical complications related to obesity. The researchers demonstrated that people with fewer bacterial species in their intestines are more likely to develop complications, such as cardiovascular diseases and diabetes. A flora with decreased bacterial richness appears to function entirely differently to the healthy variety with greater diversity.

Jeroen Raes (VIB/VUB): "This is an amazing result with possibly enormous implications for the treatment and even prevention of the greatest public health issue of our time. But we are not there yet, now we need studies in which we can monitor people for a longer period. We want to perform these types of long-term studies together with the "Vlaams Darmflora Project" (Flemish Gut Flora Project), which is only possible thanks to the selfless efforts of thousands of Flemish residents."

Obesity, a health problem

Metabolic conditions have become an epidemic partly due to the modern lifestyle without a lot of exercise and easy access to (a lot of) energy-dense food. It is expected that obesity will increase tremendously all over the world; from 400 million obese people in 2005, to more than 700 million in 2015. A trend that will persist at least until 2030. Some people appear to be more sensitive to obesity than others. Many studies over the years have examined the possible cause of this.

Bacterial richness in your intestines is associated with susceptibility to obesity

Over the last years it has become very clear that there is a link between the bacterial population in our intestines and our health. As a result, scientists also started studying the link between obesity and intestinal flora. An international consortium, including the VIB scientists Falk Hildebrand, Gwen Falony and Jeroen Raes in Brussels, examined the intestinal flora of 169 obese Danes and 123 non-obese Danes.

Jeroen Raes: "We were able to distinguish between two groups based on their intestinal flora: people with a large richness of bacterial species in their intestines and people with a few less bacterial species. A species-rich bacterial flora appeared to function differently compared to the poorer variety. It was surprising to see that obese and non-obese people were found in both groups."

The scientists did see that the group with lower species richness in the intestinal flora was more susceptible to developing obesity-related conditions and chronic inflammation. The obese people in this group are more at risk of cardiovascular conditions than the obese people in the other group. These are important results that suggest that it is not only weight gain and dietary habits that play a role in the development of medical complications in obese people.

The Flemish Gut Flora Project

The question that remains is whether these results also translate to other countries and populations. Therefore, Jeroen Raes has established the Flemish Intestinal Flora Project to follow up on these types of studies on a larger scale. Such efforts are crucial to confirm the insights acquired in smaller studies and to make an effective step towards improved treatments and medicines.


'/>"/>

Contact: Kris Van der Beken
kris.vanderbeken@vib.be
32-473-783-435
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Related biology technology :

1. Genomic Health Presents Results From First Clinical Decision Making Study of Oncotype DX® Colon Cancer at the 2012 Gastrointestinal Cancers Symposium
2. Micropharma announces timeline to commercial launch of worlds first ingestible gastrointestinal sampling device
3. Vince & Associates, Brad Vince Expands Early Phase Gastrointestinal Capabilities
4. Sequenom Announces Participation at the Lazard Capital Markets 8th Annual Healthcare Conference
5. Bayer HealthCares Cotavance® Drug Eluting Balloon With Paccocath® Technology Reduced Five-Year Target Lesion Revascularization Rates by 59 Percent in PAD Patients Compared to Those Treated With Uncoated Balloon
6. Organovo to Present at Lazard Capital Markets 8th Annual Healthcare Conference
7. Pharmasset to Present at the Lazard Capital Markets Healthcare Conference
8. inVentiv Health Selected to Provide Sales Operations Support for Santarus
9. Masimo to Present at 23rd Annual Piper Jaffray Health Care Conference
10. Hong Kong Department of Health to Combat Sudden Cardiac Arrest With Powerheart AEDs
11. Nations Best Health Care Organizations for Patient Satisfaction, Core Measures Honored by Press Ganey
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... At present, the Biotech sphere is in a ... volatility is what makes this industry interesting to consider. Here ... (NASDAQ: SNTA ), CTI BioPharma Corp. (NASDAQ: ... and Heat Biologics Inc. (NASDAQ: HTBX ). Sign ... these stocks at: http://www.activewallst.com/register/ ...
(Date:5/26/2016)... Despite the volatility that continues to envelop the ... research on ActiveWallSt.com directs the investor community,s focus on the ... ), Cerus Corp. (NASDAQ: CERS ), Arrowhead Pharmaceuticals ... Inc. (NASDAQ: FPRX ). Register with us today ... On Wednesday, shares in Massachusetts ...
(Date:5/25/2016)... ... May 25, 2016 , ... Lajollacooks4u has become a rising hotspot for specialized ... of its top attractions. Fortune 500 companies, such as Illumina, Hewlett-Packard, Qualcomm and ... intimate team-building experience. , Each event kicks off with an olive oil and salt-tasting ...
(Date:5/25/2016)... ... May 25, 2016 , ... The ... by the Office of the National Coordinator for Health IT (ONC) outlining a ... clinically relevant data were available when and where it was needed. The organization ...
Breaking Biology Technology:
(Date:4/15/2016)... 2016 Research and Markets has ... Market 2016-2020,"  report to their offering.  , ... ,The global gait biometrics market is expected to ... period 2016-2020. Gait analysis generates multiple ... used to compute factors that are not or ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys ... founding CEO, Barrett Bready , M.D., who returned ... of the original technical leadership team, including Chief Technology ... of Product Development, Steve Nurnberg and Vice President of ... to the company. Dr. Bready served as ...
(Date:3/22/2016)... PROVO and SANDY, Utah ... Ontario (NSO), which operates the highest sample volume laboratory ... and Tute Genomics and UNIConnect, leaders in clinical sequencing ... announced the launch of a project to establish the ... panel. NSO has been contracted by ...
Breaking Biology News(10 mins):