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Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium
Date:10/30/2008

f Koreans. This genetic variation was associated with favorable health parameters, including low body mass index, high HDL cholesterol, and low triglycerides. Individuals with this genetic pattern were at very low risk for early onset heart disease or heart attack.

About Coronary Artery Disease

Coronary artery disease (CAD) is an inflammatory disease in which plaque builds up inside the coronary arteries. These arteries supply your heart muscle with oxygen-rich blood. Plaque is made up of fat, cholesterol, and other substances found in the blood. When plaque builds up in the arteries, the condition is called atherosclerosis. Variation in interleukin genes has shown to be associated with different degrees of CAD risk.

About Cardiovascular Disease Risk in Asia

Cardiovascular disease (CVD), which includes heart, stroke and blood vessel disease, is the world's leading killer, accounting for nearly 30 percent, or about 17 million, of total deaths in 2003. While deaths from heart attacks have declined more than 50 percent in many industrialized countries since the 1960's, death rates from CAD are on the rise. Urban China saw an increase greater than 50 percent from 1988 to 1996. In total, 80 percent of global CVD-related deaths occur in low and middle-income nations, including most countries in Asia.

A recent World Health Organization report identifies the increasing importance of cardiovascular disease in developing countries. A study published in the International Journal of Epidemiology (2003; 32:563-572) concluded that in both Asian and non-Asian populations in the Asia-Pacific region, total cholesterol is strongly associated with both the risk of coronary artery disease and ischemia. Rising population-wide levels of cholesterol would be expected to contribute to a substantial increase in the overall burden of cardiovascular disease in this region. If the pattern is similar to incidence rates seen in the United States, it is estimate
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SOURCE Interleukin Genetics, Inc.
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