Therapeutic Hepatitis C Virus (HCV) vaccine: Results from a Phase II study of Intercell's HCV vaccine candidate were reported in 2008, and demonstrated a statistically significant viral load reduction at 2 weeks (0.2 log) and 6 months (0.46 log) after the last vaccination. Currently, no vaccine against HCV is available and the present standard therapy of Interferon and Ribavirin has limited efficacy and severe side effects, leading to high dropout rates. Intercell anticipates that a partnership to conduct combination studies with its vaccine will be identified in 2010. Consequently, Intercell and Novartis terminated their partnership in this field in February 2010. Intercell received a non-exclusive, worldwide license from Novartis to further develop and commercialize its therapeutic HCV vaccine under Novartis' strong genomic patent portfolio in HCV.
Tuberculosis vaccine: Phase I clinical programs are proceeding according to plan. These programs are based on a partnership between Intercell, Statens Serum Institut, sanofi-aventis, and the AERAS Global Tuberculosis Foundation. Further clinical data is expected during 2010.
Key Financial Information
in EUR thousand Year ended December 31, --------------- ----------------------- 2009 2008
|SOURCE Intercell AG|
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