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InterMune to Present Abstracts on HCV Protease Inhibitor ITMN-191 and HCV Development Program at the EASL Meeting
Date:3/18/2009

BRISBANE, Calif., March 18 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) today announced that five abstracts from clinical and in-vitro studies of ITMN-191 (R7227) and the company's research programs related to the hepatitis C virus (HCV) have been accepted for presentation at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL, April 22-26, 2009 in Copenhagen, Denmark). The abstracts are expected to be available at www.easl.ch. ITMN-191 is an HCV NS3 protease inhibitor, being developed in collaboration with Roche.

Dan Welch, Chairman, Chief Executive Officer and President of InterMune, said, "Collectively, these abstracts demonstrate that ITMN-191 is a promising, potent antiviral compound for the treatment of HCV and underscore our company's continued progress in the research of new compounds for HCV patients."

Presentations of ITMN-191 Clinical Results

  • Antiviral Activity and Safety of ITMN-191 in Combination with Peginterferon alfa-2a and Ribavirin in Patients with Chronic Hepatitis C Virus (HCV).
  • Incidence of Virologic Escape Observed During ITMN-191 Monotherapy is Genotype Dependent, Associated with a Specific NS3 Substitution, and Suppressed Upon Combination with Peginterferon alfa-2a/Ribavirin.

Additional InterMune Presentations at EASL

Titles of additional InterMune posters to be presented at EASL are as follows:

  • Combination of the NS3/4A Protease Inhibitor ITMN-191 with the Allosteric NS5B Polymerase Inhibitor ITMN-8020 Enhances Replicon Clearance and Reduces the Emergence of Drug Resistant Variants.
  • Discovery of Potent, Bio
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SOURCE InterMune, Inc.
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