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InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF
Date:2/3/2009

fenidone was approved for use in IPF patients in Japan and is marketed as Pirespa(R) by Shionogi in that country.

About the Marnac Agreement

In November 2007, InterMune concluded an agreement with Marnac, Inc. and with co-licensor KDL GmbH, the licensors for pirfenidone. The agreement involved the acquisition of patents and the elimination of all future royalties due to Marnac in exchange for total upfront payments of $13.5 million. Contingent acquisition payments of up to an additional $53.5 million would be made by InterMune only upon successful achievement of certain clinical development and regulatory milestones. InterMune provided additional details of this agreement in its press release dated November 26, 2007.

About IPF

Idiopathic pulmonary fibrosis (IPF) is a disabling and ultimately fatal disease that affects approximately 250,000 people in the United States and Europe combined, with approximately 30,000 new cases reported per year in each of the United States and Europe.

IPF is characterized by inflammation and scarring (fibrosis) in the lungs, hindering the ability to process oxygen and causing shortness of breath (dyspnea) and cough and is a progressive disease, meaning that over time, lung scarring and symptoms increase in severity. The median survival time from diagnosis is two to five years, with a five-year survival rate of approximately 20%. Patients diagnosed with IPF are usually between the ages of 40 and 70, with a median age of 63 years and the disease tends to affect slightly more men than women. There are no medicines approved by the FDA or EMEA for the treatment of IPF.

Webcast Details

InterMune will host a teleconference and webcast, with accompanying slide presentation, today at 8:00 a.m. EST to discuss results from the CAPACITY program.

To access the live teleconference, dial 888-799-0528 (U.S.) or 97
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SOURCE InterMune
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