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InterMune Reports First Quarter 2011 Financial Results and Business Highlights
Date:4/28/2011

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  • InterMune has a number of granted, allowed and pending patent applications in Europe relating to Esbriet's formulation and use in IPF patients.  InterMune reported that three such patents have now been granted by the European patent office.  The first relates to the effect of food on the pharmacokinetics and safety of pirfenidone in IPF patients and expires in late 2026.  A second relates to the safe usage of Esbriet in patients who develop elevation in liver transaminase levels, which expires in late 2029, and a third relates to the titration of the dosing of Esbriet at the initiation of therapy, which expires in late 2027.  In addition, the company has two other patents that have been allowed, one which relates to the contraindicated use of pirfenidone in combination with fluvoxamine, and the second which relates to discontinuing smoking in connection with the use of pirfenidone. Both of these patents expire in 2030. Several other patents are still under review in Europe.
  • InterMune announced that it launched in April a program that allows qualified physicians to make Esbriet available to their IPF patients, if they meet certain pre-specified medical criteria and conditions, free of charge before Esbriet is commercially available throughout Europe.  The program is a so-called Named Patient Access Program (NPP) and has begun enrolling patients.  The NPP is focused on the major countries of Europe and is expected to continue for approximately 12 months.
  • InterMune today reported that pirfenidone will be the subject of an oral presentation and a poster discussion at the International Conference of the American Thoracic Society (ATS), May 13-18 in Denver, Colo.:
  • C93 Oral Presentation: The Effect of Treatment with Pirfenidone on Longitudinal Change in Lung Volume in Patients with Idiopathic Pulmonary Fibrosis (IPF): A Meta-Analysis of Outcomes in Four Randomized Controlled Clinical Trials
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  • SOURCE InterMune, Inc.
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