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Intellect Neurosciences Enters Collaboration Agreement with Leading Alzheimer's Research Group at University of California Irvine to Test First in Class Dual Target Vaccine
Date:4/17/2012

NEW YORK, April 17, 2012 /PRNewswire/ -- Intellect Neurosciences, Inc. (OTCBB:ILNS), a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic agents for the treatment of Alzheimer's and other neurological diseases today announced it has entered into a collaboration agreement with the University California, Irvine to test RV03 a preclinical, first-in-class, dual acting peptide vaccine candidate to induce an immune response against beta amyloid and delta tau.  Delta tau is thought to be the earliest pathological form of tau protein prior to the formation of neurofibrillary tangles in the brain of Alzheimer's patients.  RV03 will be tested for both its therapeutic and prophylactic potential.  

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Intellect will be collaborating with Dr. Frank LaFerla, Chancellor's Professor and Chair, Neurobiology and Behavior School of Biological Sciences, Director, Institute for Memory Impairments and Neurological Disorders and his team, in collaboration with Dr. Kim Green.   Previously, Dr. LaFerla's group proposed a novel mechanism establishing a causative link between the accumulation of beta amyloid in the brain of Alzheimer's patients and the formation of neurofibrillary tangles comprised of tau protein.  This was an important step towards explaining how these two different proteins act synergistically to cause irreversible damage and death of nerve cells. 

"These studies at the University of California at Irvine are an essential next step in the development of our RV03 program, and we anticipate positive results.  Once complete, we will be ready to embark on an aggressive development program to test RV03 in human clinical trials," said Dr. Daniel Chain, Chairman and CEO of Intellect Neurosciences.   "We look forward to working with
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SOURCE Intellect Neurosciences, Inc.
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