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Intarcia Therapeutics Appoints Nancy Thornberry to Board of Directors
Date:12/2/2013

etes – Nancy knows very well that many patients around the world still need new treatment alternatives that can provide even better medical control, as well as markedly better compliance rates with their medicines over time. "I am very interested in new medicines that have the potential to be game changers in the treatment of serious diseases, and I see opportunities at Intarcia not only with ITCA 650 but in the Company's longer-term pipeline initiatives.  I look forward to working with the Board and senior leadership to help to advance these programs and create the type of clinical outcomes success that will benefit patients."

About ITCA 650
ITCA 650 (a once- or twice-yearly continuous subcutaneous delivery of exenatide) is being developed for the treatment of type 2 diabetes. The investigational therapy employs Intarcia's proprietary technology platform involving a matchstick-size, miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy, and the company's proprietary formulation technology, which maintains stability of therapeutic proteins and peptides at human body temperatures for extended periods of time.

Data from Intarcia's ITCA 650 Phase 2 program have demonstrated significant and sustained reductions in HbA1c and body weight over 48 weeks of treatment with a marked reduction in the GI adverse events typically associated with the self-injection products in this class. ITCA 650 is an investigational new therapy and is not currently approved by any regulatory authority. Exenatide, the active agent in ITCA 650, is a glucagon-like peptide-1 (GLP-1) receptor agonist currently marketed globally as twice-daily and once-weekly self-injection therapies for type 2 diabetes. Upon approval, ITCA 650 would represent the first injection-free GLP-1 therapy that can deliver a full year of treatment from a single placement. Intarcia's robust intellectual property portfolio protects ITCA 650
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SOURCE Intarcia Therapeutics, Inc.
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