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Intarcia Therapeutics Appoints Nancy Thornberry to Board of Directors
Date:12/2/2013

numerous and significant achievements. Those achievements came early as Nancy provided critical enzymology support to the angiotensin converting enzyme (ACE) inhibitor project for the treatment of hypertension, and multiple other targets.  Her early accomplishments also include the identification of the first caspase, interleukin-1b converting enzyme (ICE/caspase-1), and contributions to the discovery of the target of ezetimibe, the active ingredient in ZETIA™.

In 1999 Nancy became the Director of Enzymology, and then in 2001 the Director of Metabolic Disorders. It was during this same time that the full magnitude of Nancy's contributions became apparent. She initiated the DPP-4 program in 1999, and co-led the team resulting in the discovery of Januvia™ (sitagliptin) in 2001. Sitagliptin is currently the #1 branded oral agent for the treatment of type 2 diabetes, and the largest selling product in Merck history. 

In 2007 Nancy became a Vice President and Worldwide Basic Research Head for Diabetes and Obesity, and then again was promoted in 2009 to SVP and Franchise Head of Diabetes and Obesity. Finally in 2011 Nancy became SVP and Franchise Head of Diabetes and Endocrinology for Merck Research Laboratories. In this role, she was responsible for strategy and pipeline management for R&D in the areas of diabetes, osteoporosis, fertility, and contraception, and numerous programs advanced under her leadership.

In addition to a prolific publishing record, Nancy has been awarded numerous times for her accomplishments, including in 2011 the PhRMA Discoverers Award. She has guest lectured at prestigious venues, as well as chaired many key scientific and medical sessions.

Nancy explained that she was drawn to the Intarcia Board opportunity because of the Company's capabilities and culture of innovation, and her assessment that ITCA 650 has the potential to make a real difference in the lives of patients with type 2 diab
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SOURCE Intarcia Therapeutics, Inc.
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