Navigation Links
Insmed and Premacure Cite Study Results Demonstrating Potential Effectiveness of IPLEX(TM) in Preventing Blindness in Premature Infants
Date:9/23/2008

- Premacure to Initiate Phase II Trial for IPLEX(TM) in Retinopathy of Prematurity -

RICHMOND, Va. and UPPSALA, Sweden, Sept. 23 /PRNewswire-FirstCall/ -- Insmed Inc. (Nasdaq CM: INSM), a developer of follow-on biologics (FOBs) and biopharmaceuticals, and Premacure AB, a biopharmaceutical company dedicated to the development of diagnosis and prevention of complications in neonates due to premature birth, today noted the presentation of clinical study results demonstrating that Insmed's IPLEX(TM) product, a complex of recombinant human insulin-like growth factor (rhIGF-I) and its predominant binding protein IGFBP-3 (rhIGFBP-3), increased serum IGF-I levels into the normal range in significantly premature infants. Premacure is developing IPLEX(TM) as a potential treatment for Retinopathy of Prematurity (ROP) via a Material Transfer Agreement with Insmed.

These most recent study results were reported today at the European Society for Pediatric Endocrinology 47th annual meeting, Istanbul, Turkey, by Investigators from the Harvard Medical School, Boston MA, and the University of Gothenburg, The Karolinska Institute, Stockholm, Lund University, Sweden, in a poster entitled "Pharmacokinetic study of recombinant human (rh) insulin-like growth factor/rh IGFBP-3 complex administered to very low birth weight infants."

"The possibility of preventing ROP and other complications of prematurity by replicating the in utero environment after infants are born prematurely and lose the factors normally provided by the maternal environment is very exciting," said Lois Smith, Professor of Ophthalmology, Harvard Medical School, Children's Hospital Boston. "This work showing that it is now possible to raise the serum level of IGF-1 and IGFBP-3 to normal in utero levels in these fragile infants with IGF-1 / IGFBP-3 deficiency is a critical step in the development of interventions that prevent ROP. Since we have shown that low IGF-1 is associated with ROP, this of
'/>"/>

SOURCE Insmed Inc.; Premacure AB
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Insmed to Present at Biosimilars 2008 Conference
2. Insmed to Present at BioPharm Asia 2008 Conference
3. Insmed Announces Financial Results for Second Quarter and Six-Months Ended June 30, 2008
4. Insmed CEO to Present at Drug Discovery & Development Conference
5. Insmed to Host Second Quarter 2008 Conference Call
6. Insmed Partners With Bill Thomas, Former House Ways and Means Chairman, as Strategic Advisor
7. Insmed Retains RBC Capital Markets as Strategic Financial Advisor
8. Insmed to Present at Collins Stewart Fourth Annual Growth Conference
9. Insmed to Request Hearing Before NASDAQ Panel to Review NASDAQ Staff Determination
10. Insmed Announces First Quarter 2008 Financial Results
11. Insmed to Present at CBI Follow-On Biologics Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/17/2014)... PRINCETON, N.J. , Nov. 17, 2014 /PRNewswire/ ... Company), a late-stage biopharmaceutical company developing products that ... inflammation, oncology and biodefense, announced today the formation ... medical/clinical strategic guidance to the Company as it ... (synthetic hypericin) for the treatment of cutaneous T-cell ...
(Date:11/15/2014)... 2014 Collaborative Consulting, a privately held, ... one of the Boston Globe’s “Top Places to Work ... in Massachusetts to receive the honor. , The Boston ... care of their most valuable resource: the people who ... and are based on an array of criteria, including ...
(Date:11/15/2014)... The International Society for ... the society’s Governing Board has grown with the ... scientific officer and Dr. Charles Simonton, divisional vice ... Mr. Rowe and Dr. Simonton are both ... , Dr. Nabil Dib, ISCTR President stated, ...
(Date:11/15/2014)... The "Operating Room Management Market by Product (Data ... operating room Scheduling), by Component (Software, Services), by ... 2019.” defines and segments the operating room management ... by product, such as data management, anesthesia, surgical ... volumes of operating room management market by applications ...
Breaking Biology Technology:Soligenix Announces Formation of Cutaneous T-Cell Lymphoma Medical Advisory Board 2Soligenix Announces Formation of Cutaneous T-Cell Lymphoma Medical Advisory Board 3Soligenix Announces Formation of Cutaneous T-Cell Lymphoma Medical Advisory Board 4Soligenix Announces Formation of Cutaneous T-Cell Lymphoma Medical Advisory Board 5Soligenix Announces Formation of Cutaneous T-Cell Lymphoma Medical Advisory Board 6Collaborative Consulting Honored with Boston Globe Top Places to Work 2014 2International Society for Cardiovascular Translational Research Governing Board Adds Medical Industry Leaders 2Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 2Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 3Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 4
... at Sanford-Burnham Medical Research Institute (Sanford-Burnham) and the Medical ... botulinum neurotoxin, a potential bioterrorism agent, survives the hostile ... human body. Their study, published February 24 in ... neurotoxin together with its bodyguard, a protein made simultaneously ...
... such as thistles, buttercups and clover could be critical ... according to Researchers funded by the Biotechnology and Biological ... Science , researchers from the University of Bristol detail ... commonly found on farms throughout the UK and the ...
... create are stunning. Others are not mismatched fonts, poorly ... A deluge of data presents a challenge to amateur designers, ... the figure,s main message. A group of University of Washington ... and those in design. The new Design Help Desk, similar ...
Cached Biology Technology:Disarming the botulinum neurotoxin 2Disarming the botulinum neurotoxin 3Farm 'weeds' have crucial role in sustainable agriculture 2Design eye for the science guy: Drop-in clinic helps scientists communicate data 2Design eye for the science guy: Drop-in clinic helps scientists communicate data 3
(Date:11/11/2014)... -- Forensicon, Inc., a Chicago -based digital ... promotion of Yaniv Schiff from Senior Computer ... new role as Director, he will lead company efforts ... and provide leadership within the company,s digital forensics practice ... Schiff joined Forensicon in 2006 and ...
(Date:11/7/2014)... Calif. , Nov. 7, 2014  In conjunction with ... Police Departments, The Community Foundation of the Verdugos ... DNA JUSTICE PROJECT," a $250,000 initiative to keep ... initial phase. In its first six months of existence, the ... needed evidence support for local law enforcement. "Because ...
(Date:11/6/2014)... deaths occur because of metastasis, yet progress in ... slow. , "It,s been particularly challenging to design ... research fellow in systems biology at Harvard Medical ... until after they,ve already metastasized." , Gujral and ... should help researchers better understand how metastasis begins. ...
Breaking Biology News(10 mins):Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2Migration negation 2Migration negation 3
... Columbia University Mailman School of Public Health examined the ... mass index (BMI) and obesity in New York City ... outlets is associated with a lower BMI and lower ... -- although far more abundant than healthy ones -- ...
... Blindness in millions of people with diseases that starve ... with a procedure being developed by researchers at Oak ... the University of Tennessee. The technique uses a ... to retinal tissue being deprived of oxygen because of ...
... 2009 (BRONX, NY) Researchers from the Albert ... have developed an onsite method to quickly diagnose tuberculosis ... mingle undetected with treatable TB strains. This study ... peer-reviewed online journal from the Public Library of Science. ...
Cached Biology News:Differences in neighborhood food environment may contribute to disparities in obesity 2ORNL, Southern Cal set sights on preventing blindness 2Einstein and Pitt researchers develop new TB test that will dramatically cut diagnosis time 2
... Cell Dissociation Buffers are membrane-filtered isotonic ... chelating agents and cell-conditioning agents in ... salt solution or Ca2+- and ... of mammalian cells from support substrates ...
Request Info...
Mouse monoclonal [7A6] to NFAT2 ( Abpromise for all tested applications). entrezGeneID: 4772 SwissProtID: O95644...
Attoglow Western Blot Enhancing Kit contains Millennium Enhancer which can significantly boost Western blot signals, and is compatible with other enhancing mechanisms to achieve multiplied enhancing ...
Biology Products: