Navigation Links
Inovio Pharmaceuticals Announces Positive Interim Results in Phase II Leukemia Trial
Date:12/6/2012

survival in the AML group. The trial is taking place at hospitals in Southampton, London and Exeter. Regulatory approval to start this clinical study was provided by the UK Medicines and Healthcare Products Regulatory Authority (MHRA) and Gene Technology Advisory Committee (GTAC).

Inovio's CEO, Dr. J. Joseph Kim, said, "We are encouraged by preliminary phase II data showing the WT1 DNA vaccine's potential, administered with our novel delivery technology, to generate T cells and robust antibodies to treat leukemia. These results follow on our recent scientific breakthrough represented by our human data showing the powerful killing effect of T cells generated by our cervical dysplasia therapeutic vaccine.

About Leukemia

Leukemia is a malignant disease (cancer) of the bone marrow and blood characterized by the uncontrolled accumulation of blood cells. Leukemia accounts for at least 300,000 new cases and 222,000 deaths worldwide each year. This high ratio of deaths-to-cases (74%) reflects the poor prognosis of leukemia in many parts of the world, where the somewhat complex treatment regimes are not available. Approximately 45,000 new cases of leukemia were diagnosed in 2008 in the US, with 20,000 deaths. This represents 3% of all cancers in the United States, and 30.4% of all blood cancers. It is estimated that approximately $3 billion is spent in the United States each year to treat leukemia.

There are five types of leukemia based on rate of development and types of blood cells affected. Two of these are being evaluated in the study discussed in this release: 1) Acute myeloid leukemia (AML), a cancer of the myeloid line of blood cells, is characterized by rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute leukemia affecting adults and its incidence increases with age. Only about one-third of those between ages 18-60 who are diag
'/>"/>

SOURCE Inovio Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7

Related biology technology :

1. Inovio Pharmaceuticals Cytomegalovirus (CMV) Synthetic Vaccine Constructs Generate Strong and Broad T-Cell Responses in Preclinical Study
2. Inovio Pharmaceuticals to Present at Noble Financial Life Sciences Conference
3. Inovios Scientific Advisory Board Chairman Elected as a Fellow by the American Association for the Advancement of Science
4. Inovio Pharmaceuticals to Present at Noble Financial 8th Annual Equity Conference
5. Inovio Pharmaceuticals Promotes Niranjan Sardesai to Chief Operating Officer
6. Gallus BioPharmaceuticals Announces Appointment of Senior Baxter Executive as Chief Commercial Officer
7. Ampio Pharmaceuticals, Inc. (AMPE) announces appointment of Josh Disbrow as Chief Operating Officer effective December 15, 2012
8. OncoGenex Pharmaceuticals, Inc. Provides Clinical Development Update and Reports Financial Results for Third Quarter 2012
9. Keryx Biopharmaceuticals, Inc. Announces Third Quarter 2012 Financial Results
10. Vanda Pharmaceuticals to Present at the Lazard Healthcare Conference
11. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess of $100,000 Investing In Keryx Biopharmaceuticals, Inc. To Contact the Firm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... May 23, 2013 Pusan National University ... private biotherapeutics and contract research company focused on ... cancer, announced today a publication reporting the induction ... the oncolytic and immunotherapeutic vaccinia JX-594 (pexastimogene devacirepvec; ... published in the May 15 th , 2013 ...
(Date:5/23/2013)... May 23, 2013 Watlow®, an ... complete thermal systems, recently introduced its new catalog, ... of experience in designing and manufacturing industrial heaters, ... products to serve diverse customer needs. , A ... at the beginning of the book. These options ...
(Date:5/22/2013)... 2013 iLuv Creative Technology, the premier ... the mobile lifestyle, announces they are now shipping MultiCharger-X, ... multiple iPad devices efficiently. Winner of the 2013 internationally ... Design award, MultiCharger-X is revolutionizing the way businesses, schools, ... deployed. , MultiCharger-X (iAD910) combines the ...
(Date:5/22/2013)... 22, 2013  Superior Controls, Inc. has been ... Business NH Magazine.  For the past 22 years, ... distinguish themselves with extraordinary business and civic excellence. ... this honor," said Rick Pierro ... recognition, this award is a reflection of Superior ...
Breaking Biology Technology:Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3Watlow Introduces Its New Industrial Heater Catalog 2iLuv Now Shipping the All New MultiCharger-X 2iLuv Now Shipping the All New MultiCharger-X 3Superior Controls of Seabrook, NH named Business of the Year for 2013 by Business NH Magazine 2
... HOUSTON -- Dec. 17, 2007 -- Using the latest ... physicists has discovered a surprising new electronic property in ... Earth -- lodestone, also known as magnetite. , By ... to get magnetite at temperatures colder than minus 250 ...
... Angiotech Pharmaceuticals,Inc. (NASDAQ: ANPI , TSX: ANP), ... announced that it has submitted a 510(k),application to ... its,innovative, anti-infective 5-Fluorouracil-coated (5-FU) Central Venous,Catheter (CVC)., ... a 510(k) application to,the FDA for our 5-FU ...
... ... Delivery Fleet, LONG ISLAND CITY, N.Y., Dec. 17 FreshDirect, ... today,announced that it has signed a contract with Tri-State Biodiesel to ... of 150 delivery trucks will start the switch to B5, a,blend ...
Cached Biology Technology:New property found in ancient mineral lodestone 2Angiotech Submits 510(K) To FDA For Its Innovative 5-FU CVC 2Angiotech Submits 510(K) To FDA For Its Innovative 5-FU CVC 3Angiotech Submits 510(K) To FDA For Its Innovative 5-FU CVC 4Angiotech Submits 510(K) To FDA For Its Innovative 5-FU CVC 5FreshDirect's Fleet Goes Biodiesel 2FreshDirect's Fleet Goes Biodiesel 3
(Date:5/21/2013)... "place" is increasingly being considered in the management ... new resource that can help them recognize and ... places in their lives. , Place-Based Conservation: ... co-edited by the Pacific Northwest Research Station,s Linda ... to conservation. The book is published by Springer ...
(Date:5/21/2013)... When infections occur in the body, stem cells ... multiplying and differentiating into mature immune cells that ... inflammation can deplete these cell populations, potentially leading ... as cancer. Now, a team of researchers led ... (Caltech) has found that, in mouse models, the ...
(Date:5/21/2013)... University researchers have developed a new method for ... holes in the cell surface. The technique could ... related biological fields. , Bulk electroporation a ... reversible nanopores in the cell membrane that are ... is an increasingly popular method of cell transfection. ...
Breaking Biology News(10 mins):Keeping stem cells strong 2Single-cell transfection tool enables added control for biological studies 2
... a result of increasing levels of atmospheric carbon ... according to Michael Maguire presenting at the Society ... week. Postgraduate researcher Mr Maguire, together with ... they simulated ocean acidification as predicted by current ...
... factors instrumental in triggering latent tuberculosis (TB) infection to ... researchers. New insight into the mystery is provided by ... Microbiology,s spring meeting in Edinburgh today. His work could ... Professor Russell and his group at Cornell University in ...
... surroundings by detecting hormone signals from the host, which ... hormonal messages could be a better way to treat ... good, explains Vanessa Sperandio speaking at the Society for ... bacteria, including harmful strains of Escherichia coli ...
Cached Biology News:Fat clue to TB awakening 2'Hormone therapy' for food poisoning bacteria 2
Request Info...
...
Ultra-sensitive, non-radioactive detection of rat Osteopontin...
Agarose-LE, 250 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: