Innocoll Announces Closing of $30 Million Equity Financing ...(ment of bacterial resistance. Furthermor...)

Date:12/17/2007

ment of bacterial resistance. Furthermore, diabetic ulcers are often associated with vascular disease and restricted peripheral blood flow (ischemia), which may render systemically acting antibiotics less effective. Innocoll plans to investigate CollaRx GENTAMICIN TOPICAL for the localized treatment and prevention of diabetic foot infections in patients with moderately infected, mildly infected and uninfected ulcers in a parallel series of three phase 2 multi-centered clinical trials. Currently, there are no topically applied antibiotics marketed in the U.S. that are specifically indicated for the treatment of infected diabetic foot ulcers and recent market research independently performed by L.E.K. Consulting forecast peak annual revenues approaching $270 million for the diabetic foot indication in the U.S. alone.

BUPIVACAINE SURGICAL IMPLANT has been specifically developed and formulated using Innocoll's proprietary CollaRx sponge technology for the management of post-operative pain following moderate/major abdominal, gynecological, thoracic, and orthopedic surgeries. Post-operative pain is typically controlled with narcotic analgesics such as morphine, but systemic administration of these drugs can result in unfavorable side effects including suppression of breathing, sedation, nausea and vomiting; and can also affect patient recovery. BUPIVACAINE SURGICAL IMPLANT is designed to provide pain control directly at the surgical site and thus reduce the level of additional analgesia required following surgery. The collagen matrix naturally biodegrades over a few days and the bupivacaine is released to provide local analgesia for up to 96 hours post-operatively, as demonstrated by the results of an initial clinical study performed at Wexham Park Hospital, Slough, UK, in patients undergoing hysterectomy surgery. Starting later this month, Innocoll plans to conduct a series of phase 2, multi-centered, controlled clinical trials in variou
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SOURCE Innocoll, Inc. Copyright©2007 PR Newswire. All rights reserved

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