Navigation Links
Ingenuity Systems IPA Provides Researchers with Genomic Insights Suggesting that Physical Activity Does Not Slow Muscle Aging
Date:3/21/2013

REDWOOD CITY, Calif., March 21, 2013 /PRNewswire/ -- Ingenuity® Systems, a leading provider of biomedical information and analysis solutions, today announced that its IPA technology was instrumental in elucidating a network of genetic drivers for aging. The networks determined, among other things, that muscle age was not primarily related to the biology of physical activity. The research was published in the journal PLOS Genetics in a paper from the laboratory of Professor James A. Timmons at Loughborough University in the United Kingdom (http://www.plosgenetics.org/doi/pgen.1003389).

"IPA is used at research institutions and pharmaceutical companies across the globe to generate new insights about biological systems and determine the biological meaning of scientific results. To date, there are over 7500 peer-reviewed publications using IPA," said Dr. Doug Bassett , Chief Scientific Officer and Chief Technical Officer of Ingenuity Systems. "Dr. Timmons' work clearly shows how IPA can help scientists make significant insights on their research."

Previously, research had hypothesized that resistance exercise contributed to a reverse of the aging process, yet the work carried out by Dr. Timmons' lab demonstrated that response to exercise is highly variable in humans and that pre-existing gene expression levels can predict future response to exercise. The paper also identified biological molecules that may drive the response to physical activity.

The new work coupled analysis with Ingenuity's IPA software and microarray data generated both by Dr. Timmons' laboratory as well as data sets from published literature. The analysis determined that the genetic regulators of age-related genes were distinct and unrelated to the regulators of exercise-influenced genes.

"Several papers in the recent past have asserted that exercise 'reverses' the aging process, which is a very attractive proposition – if we could simply exercise more, we would slow the aging process and potentially have fewer chronic problems," noted Dr. Timmons. "In this study, we took a different approach, measuring the variation in the products being made from the genetic code using Ingenuity's IPA, and determined that it just isn't that simple. We were able to capture the relevant networks more easily and with far less cost than traditional methods."

About Ingenuity® Systems

Ingenuity® Systems is a leading provider of biomedical information and analysis solutions for the exploration, interpretation and analysis of complex biological systems in life science research and molecular diagnostics. Today, Ingenuity's solutions are used by tens of thousands of researchers and clinicians at hundreds of leading pharmaceutical, biotechnology, academic, diagnostic and clinical institutions worldwide.


'/>"/>
SOURCE Ingenuity Systems
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Ingenuity Systems Announces Compliance with HIPAA
2. Ingenuity Systems Announces Curation of All Human Disease Implicated Genetic Variation
3. Ingenuity Systems and GeneInsight to Deliver an Interpretation and Reporting Workflow Solution to Clinical Laboratories
4. At RSNA, DR Systems Will Exhibit RIS, Reporting, Peer Review Systems
5. Clionsky Neuro Systems (CNS-Neuro) Announces Publication of Study Finding Elderly Patients Unable to Recognize Their Memory Loss
6. Dicom Systems and USARAD.com Announce Partnership and Introduce Beta Version of XMRI.com, New System by USARAD.com
7. BioPower Systems Awarded $5 Million from Victorian Government
8. Varian Medical Systems Schedules First Quarter FY2012 News Release and Conference Call
9. Quanterix Develops Microfluidic Consumable That Will Enable Next Generation Molecular Diagnostic Systems based on Single Molecule Array Technology
10. CMC Biologics Strengthens its Innovative Biomanufacturing Technology Portfolio in Continuous Perfusion Systems
11. MarketsandMarkets: Global Clinical Trial Management Systems Market Worth $1300.4 Million by 2016
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... MONTREAL , Jan. 24, 2017 /PRNewswire/ - BioAmber Inc. ... demand, the underwriters have agreed to increase the size of ... stock of the Company, together with warrants to purchase 1,842,106 ... price of US$5.50 per share of common stock (the "Exercise ... share and associated warrant (the "Public Price"). The warrants have ...
(Date:1/24/2017)... , ... January 24, 2017 , ... ... label-free graphene biosensor assays for fragment-based screening, will showcase its proprietary ... Society for Laboratory Automation and Screening (SLAS) conference in Washington, D.C. from Feb. ...
(Date:1/24/2017)... , Jan. 24, 2017 /PRNewswire/ - ProMetic Life Sciences ... announced today that its orally active lead drug candidate, ... designation by the UK Medicines and Healthcare Products Regulatory ... A PIM designation is an early ... for the Early Access to Medicines Scheme ("EAMS"), intended ...
(Date:1/24/2017)... ... January 23, 2017 , ... Oklahoma City based Sigma Blood ... for the firm’s PERFEQTA software and legacy product QC Manager 2.0. , Sigma ... team at CJBC and thrilled that they have decided to implement PERFEQTA and QC ...
Breaking Biology Technology:
(Date:12/22/2016)... -- As part of its longstanding mission to improve genetic literacy ... released its latest children,s book, titled The One ... topics of inheritance and variation of traits that are part ... school classrooms in the US. The book ... Killoran , whose previous book with 23andMe, You ...
(Date:12/20/2016)... , Dec. 20, 2016 The ... sharing, rental and leasing is stoking significant interest ... radio frequency technology, Bluetooth low energy (BLE), biometrics ... as the next wave of wireless technologies in ... access system to advanced access systems opens the ...
(Date:12/19/2016)... , España y TORONTO , 19 de ... con Northern Biologics Inc. que permitirá el desarrollo acelerado de MSC-1, ... clínicos en varios tipos de tumor en 2017, con múltiples sitios ... ... su clase con objetivo en el factor inhibidor de leucemia (LIF), ...
Breaking Biology News(10 mins):