Navigation Links
Ingenuity Systems Announces Toxicogenomics Best Practices White Paper

REDWOOD CITY, Calif., Aug. 17 /PRNewswire/ -- Ingenuity® Systems, the leading provider of information solutions for life science researchers, today announced the release of the white paper, "Best Practices for Assessing Toxicity throughout the Drug Discovery Process: Toxicogenomics."  The white paper is based on input from industry experts and shows how multidisciplinary toxicology teams in drug discovery can leverage toxicogenomics and IPA® for improved predictive toxicology and mechanistic toxicity analysis.  

Understanding the basic biological mechanisms related to toxicity is a top priority for both traditional toxicologists and other researchers whose understanding of toxicity can inform decision making at all phases of a research project.  By complementing a traditional toxicological approach with toxicogenomics, researchers get a better interpretation of large, complex amounts of data with lots of variables, can detect toxicity earlier in drug discovery for faster project decisions, and – most significantly – can better understand molecular level events that underlie toxicity.

Dr. Phil Hewitt, Head of Toxicogenomics at Merck-Serono, believes that gene expression profiling has the greatest potential for improving mechanistic insight and therefore adds a high value to Tox and Safety studies.  According to Dr. Hewitt, "Implementing toxicogenomics with traditional tox approaches will help researchers detect toxicity earlier.  Assessing toxicity is not always clear, and incorporating another source of information can only complement traditional animal studies."

IPA-Tox®, a capability within IPA, is the industry leading toxicogenomics software solution for analyzing this type of expression data to obtain actionable insights. With IPA-Tox, scientists can analyze large scale datasets (genomic and proteomic datasets, dose response datasets, etc.) in order to identify the key functions and pathways that are activated or disrupted upon treatment with a compound. IPA-Tox also links expression data to clinical pathology endpoints for mechanistic hypotheses generation and identification of mechanism of toxicity.  

To download the complimentary white paper and learn more about toxicogenomics best practices using IPA, please go to:

The latest release of IPA includes a significant increase in molecular toxicology content with a focus on key clinical and pre-clinical pathology endpoints as prioritized by customers across key tissues of liver, kidney, and heart.  You can sign up for a free trial of IPA-Tox at:

About IPA®

IPA is an all-in-one software application that enables researchers to model, analyze, and understand the complex biological and chemical systems at the core of life science research.  

For more information visit:

About Ingenuity® Systems

Ingenuity Systems is a leading provider of information solutions and custom services for life science researchers, computational biologists and bioinformaticists, and life science industry suppliers. For more information visit:

SOURCE Ingenuity Systems
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Ingenuity Systems Announces New Distributor for Greece, Turkey and the Balkans
2. Ingenuitys Technology Powers BD Cell Pathways Tool on New BD Biosciences Website
3. Sigma-Aldrich Honored With CIO 100 Award for Innovative Web Research Tool, Your Favorite Gene powered by Ingenuity
4. Sigma-Aldrich Launches Your Favorite Gene Powered by Ingenuity
5. Delcath Systems Announces the Sale of 5,185,000 Shares of Common Stock
6. Axela Acquires Xceed Molecular Creating Powerhouse in Robust and Easy-to-Use Systems for Translational Medicine
7. FRC Systems International State-of-the-art Industrial Wastewater Treatment Systems
8. Dehaier Medical Systems Reaffirms Earnings Estimate of $0.80 EPS for FY 2010
9. Dehaier Medical Systems Signs $1.6 Million Oxygen-Chip Sales Contract
10. delSECUR CORPORATION Announces Organizational Update as QTECH SYSTEMS INC. Expands Leadership Team
11. Melissa Kemp, Ph.D., Wins the Council for Systems Biology in Boston (CSB2) Award Sponsored by Merrimack Pharmaceuticals, Inc.
Post Your Comments:
(Date:11/24/2015)... --> --> ... by Transparency Market Research, the global non-invasive prenatal testing ... 17.5% during the period between 2014 and 2022. The ... Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 ... to reach a valuation of US$2.38 bn by 2022. ...
(Date:11/24/2015)... ... November 24, 2015 , ... In harsh industrial ... points for in-line sensors can represent a weak spot where leaking process media ... of retractable sensor housings , which are designed to tolerate extreme process conditions. ...
(Date:11/24/2015)... LOS ANGELES , Nov. 24, 2015 ... a biotechnology company focused on the discovery, development and ... Marban , Ph.D., Chief Executive Officer, is scheduled to ... December 1, 2015 at 10:50 a.m. EST, at The ... York City . . ...
(Date:11/24/2015)... ... , ... Whitehouse Laboratories is pleased to announce that it has completed construction ... dedicated to basic USP 61, USP 62 and USP 51 testing specific to raw ... and micro testing performed by one supplier. Management has formally announced that ...
Breaking Biology Technology:
(Date:11/9/2015)... 09, 2015 ... the "Global Law Enforcement Biometrics Market ... --> ) has announced the ... Biometrics Market 2015-2019" report to their ... ( ) has announced the addition ...
(Date:10/29/2015)...   MedNet Solutions , an innovative SaaS-based eClinical ... research, is pleased to announce that it has been ... one of only three finalists for a 2015 ... Growing" category. The Tekne Awards honor Minnesota ... innovation and leadership. iMedNet™ eClinical ...
(Date:10/29/2015)... Oct. 29, 2015  Connected health pioneer, Joseph ... explosion of technology-enabled health and wellness, and the business ... The Internet of Healthy Things . ... smartphones even existed, Dr. Kvedar, vice president, Connected Health, ... care delivery, moving care from the hospital or doctor,s ...
Breaking Biology News(10 mins):