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Increased fertility rate for IVF patients achieved by new equipment design
Date:2/29/2012

A novel system for processing embryos during IVF treatment has been shown to significantly improve the chances of pregnancy by more than a quarter.

Pioneered by a Newcastle team of fertility experts at the University and within the NHS, the innovative design of interlinked incubators provides a totally enclosed and controlled environment within which every step of the IVF process can be performed.

Research published today in the journal PLoS ONE reveals that the introduction of the new system into the Newcastle Fertility Centre at Life, part of the Newcastle Hospitals NHS Foundation Trust, resulted in a 27% increase in pregnancy rate compared with conventional equipment used in IVF treatment labs.

Traditionally, in IVF procedures embryos are cultured in incubators, which provide a controlled environment. However, it is necessary to check embryo development under the microscope.

This generally involves removing them from the controlled environment of the incubators, which may be harmful. The system developed by the Newcastle team overcomes this problem by enabling all procedures to be conducted within an enclosed and controlled environment.

Initially the new system was tested extensively to make sure that it maintained stable environmental conditions (for air quality and temperature). Subsequent studies on embryos donated to research showed a significant increase in the proportion of embryos developing normally over a period of 6-7 days.

After introduction into the laboratories at Newcastle Fertility Centre at Life, the team were able to compare the treatment outcomes over a period of three years. The study, found that 45% achieved a clinical pregnancy compared to 32% and 35% in each of the preceding two years. This represents a minimum increase of 27% in the clinical pregnancy rate; a clinical pregnancy means that a heart beat was seen on the scan at 7 weeks gestation.

The study,
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Contact: Karen Bidewell
karen.bidewell@ncl.ac.uk
44-191-222-6972
Newcastle University
Source:Eurekalert

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