Navigation Links
InSightec Resumes Clinical Trials for Non-Invasive Treatment of Brain Tumors

HAIFA, Israel, September 24 /PRNewswire/ -- InSightec Ltd. has begun the second stage of its FDA approved Phase I clinical trial for non-invasive treatment of brain tumors using MR guided Focused Ultrasound Surgery on the ExAblate(r) system.

The objectives of the study are to evaluate the safety of focused ultrasound delivered through an intact skull and to estimate the effect of the thermal ablation on the tumors. Patients with recurrent and inoperable glioblastomas or cerebral metastases are being recruited for this study.

ExAblate(r) uses high-intensity focused ultrasound waves to ablate (destroy) tissue in combination with Magnetic Resonance Imaging (MRI). The system provides visualization of the tumor and acoustic energy beam path as well as real time thermal feedback that allows the physician to monitor and control the treatment process.

Three patients with recurrent glioblastoma have already been treated at Brigham and Women's Hospital in Boston, evaluating the ability of the ExAblate system to safely reach a targeted tumor. Based on the safety profile submitted for review, the FDA recently approved the continuation of the trial.

"The ExAblate MRgFUS technology has significant potential as a non-invasive and non-ionizing tumor therapy, and offers an important potential alternative or adjunct to radiation therapy, and eventually, for brain surgery" says Ferenc Jolesz, MD Professor of Radiology, Brigham and Women's Hospital, Boston MA.

Dr. Peter Black, Professor of Neurosurgery at the Brigham and Women's Hospital and co-director of the study adds that "The challenge of brain tumor surgery is to achieve complete tumor removal or the greatest possible extent of tumor reduction without causing brain injury. This feasibility study will significantly advance our understanding of the potential of this technology for brain tumor treatment and if successful, prepare the way for a clinical efficacy study."

Further details of ExAblate technology and clinical experience can be found at Details about the clinical trial can also be found at Clinical (;jsessionid= DA645CDD9781968B8BF5161676409C8B?order=4)

(Due to the length of this URL, it may be necessary to copy and paste this hyperlink into your Internet browser's URL address field. Remove the space if one exists.)

About ExAblate

The ExAblate(r) is the first system to use the breakthrough MRgFUS technology that combines MRI - to visualize tissues in the body, plan the treatment and monitor in real time treatment outcome - and high intensity focused ultrasound to thermally ablate uterine fibroid tissue. MR thermal feedback, provided uniquely by the system, allows the physician to control and adjust the treatment in real time to ensure that the targeted tumor is fully treated and surrounding tissue is spared. ExAblate received FDA approval for the treatment of symptomatic uterine fibroids in October 2004. ExAblate has been recognized for its innovation and potential to serve mankind and has been awarded the 2004 European Union's Information Society Technologies grand prize, The Wall Street Journal's 2004 Technology Innovation Awards, Advanced Imaging's 2005 Solutions of the Year and, the Red Herring 100 Europe 2007 Award.

About InSightec

InSightec Ltd. is a privately held company owned by Elbit Medical Imaging (EMI), General Electric, MediTech Advisors, LLC and employees. It was founded in 1999 to develop the breakthrough MR guided Focused Ultrasound technology and transform it into the next generation operating room. Headquartered near Haifa, Israel, the company has over 135 employees and has invested more than $100 million in research, development, and clinical investigations. Its U.S. headquarters are located in Dallas, Texas. For more information, please go to:

Contact Information:

InSightec Ltd.

Tel: +972-4-813-1313


For media inquiries:

Fern Lazar

Lazar Partners, Ltd.

Tel: +1-212-867-1762


For medical inquiries:

Black, Peter Mclaren,M.D.,Ph.D.

Prof. of Neurosurgery

Department of Neurosurgery

Brigham and Women's Hospital

Harvard Medical School

75 Francis Street, Boston MA 02115

Tel: +1-617-732-6600

Fax: +1-617-734-8342


Ferenc A. Jolesz, MD.

B. Leonard Holman Professor of Radiology

Vice Chairman for Research

Director, Division of MRI and Image Guided Therapy Program

Department of Radiology

Brigham and Women's Hospital

Harvard Medical School

75 Francis Street, Boston MA 02115

Tel: +1-617-732-5961

Fax: +1-617-582-6033


For media inquiries Brigham and Women's Hospital:

Jessica Podlaski

Media Relations Coordinator

Brigham and Women's Hospital

321 Columbus Avenue

Boston, MA 02116

Phone: +1-617-534-1603

Fax: +1-617-534-1610

Pager: +1-(617)-732-6660 #33916

SOURCE InSightec Ltd
Copyright©2007 PR Newswire.
All rights reserved

Related biology technology :

1. BioRobot MDx standardize your automated protocols in clinical laboratories
2. What patients want: A story of choice, clinical trials & evidence-based medicine
3. ZyStor seeks to raise $15M for clinical trials
4. Prodesse begins clinical trials for flu virus detection
5. ConjuGon raises $3.3 million to fund clinical trials
6. Cancer-fighting agent heads for clinical trials
7. Quintessence cancer treatment chosen for clinical studies
8. Third Wave reports clinical growth, continued loss
9. Childrens expanding use of Sunrise Clinical Manager
10. Life-sciences conference to feature novel research with clinical potential
11. $14 million grant to drive clinical research at UW
Post Your Comments:
(Date:10/9/2015)... 2015 On October 8, the Honorable Doris ... statement recognizing the third annual International Plasma Awareness Week ... by the Plasma Protein Therapeutics Association (PPTA) ... , Raise global awareness about plasma donation ... and improving lives , Increase understanding about lifesaving ...
(Date:10/9/2015)... SAN DIEGO , Oct. 9, 2015  DePuy ... ® Flex with Q-PACK ®  Technology**, the ... use in trauma-related extremity procedures (foot and ankle, hand ... The announcement was made here at the 2015 Orthopaedic ... (provides a natural scaffold for new bone growth) ...
(Date:10/9/2015)... San Francisco, CA (PRWEB) , ... October 09, 2015 , ... ... with a study that aims to better understand the relationship between weight management and ... more frequently and more accurately from participants using an iPhone app. , The uBiome ...
(Date:10/8/2015)... 8, 2015  Sorrento Therapeutics, Inc. (NASDAQ:  SRNE; ... for cancer and associated pain, announced today that Dr. Henry ... presenting at the Aegis Capital Corporation 2015 Growth ... Capital Corporation 2015 Growth ConferenceDate:Friday, October 9, 2015Time:10:00 ... @ The Wynn in Las Vegas, NV , ...
Breaking Biology Technology:
(Date:10/8/2015)... , Oct. 8, 2015 Synaptics ... human interface solutions, announced today that it will ... fiscal 2016 on Thursday, October 22, 2015, after ... a corresponding conference call for analysts and investors ... which management may discuss forward-looking information.    ...
(Date:10/6/2015)... LAKE CITY , Oct. 6, 2015 ... company, announced today that it has signed a contract ... monitoring services across the full range of sentences under ... Group,s President of the Americas. "This contract with the ... region of the US and advances our position as ...
(Date:9/30/2015)...  With nearly 300,000 Americans living with spinal cord ... to reach 12,500 annually, the role of Independent Living ... Independent Living (SCRS-IL) is increasingly important. SCRS-IL is ... opening doors to independence for individuals with SCIs ... assistive technology services and education. "In serving ...
Breaking Biology News(10 mins):