Navigation Links
In the battle to relieve back aches, Cornell researchers create bioengineered spinal disc implants
Date:8/1/2011

nnulus, made of a stiff material, and the inner circle, the nucleus, made of a gel-like substance that gets pressurized and bears weight.

Bonassar's lab, which focuses on the regeneration and analysis of musculoskeletal tissue, engineered artificial discs out of two polymers collagen, which wraps around the outside, and a hydrogel called alginate in the middle. They seeded the implants with cells that repopulate the structures with new tissue. Remarkably, as opposed to artificial implants today that degrade over time, the scientists are seeing that the implants get better as they mature in the body, due to the growth of the cells.

"Our implants have maintained 70 to 80 percent of initial disc height. In fact, the mechanical properties get better with time," says Bonassar.

The implants would treat a broad category of illness called degenerative disc disease a leading cause of disability worldwide. According to Hrtl, an increasing number of patients need treatment or surgery from the degeneration of the intervertebral disc. A surgical procedure approved by the FDA in 2005 involves removing the disc completely and replacing it with an implant made of a combination of metal and plastic, with the aim of mimicking the normal movement of the lumbar and spine.

"Bone or metal or plastic implants are complicated structures which come with a mechanical risk of the structures moving around, or debris from the metal or plastic particles accumulating in the body from wear and tear," says Hrtl.

From a biological perspective, the new discs could create a "huge advantage" over traditional implants because of how they integrate and mature with the vertebrae. This major surgery would become less invasive, safer and come with fewer long-term side effects, he says.

The scientists began collaborating on the project in 2006, first funded by an Ithaca-Weill seed grant. Since then, the project has moved into animal testing stages,
'/>"/>

Contact: Syl Kacapyr
vpk6@cornell.edu
607-255-7701
Cornell University
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. BD and FIND Achieve Milestone in Global Battle Against MDR-TB
2. Battle of the sexes, fruit-fly style
3. Magellan Biosciences Announces Agreement with Bruker to Provide Microbiology Tools to Battle Drug Resistance
4. New approaches, technological advances offer promise for obesity treatment
5. Polycystic Kidney Disease Assay at Cornell University Uses Transgenomics Surveyor Nuclease & WAVE Technology
6. Gamida Cell Announces Feasibility Study With Weill Cornell Medical College
7. Under new leadership, Kavli Institute at Cornell evolves from a think tank to a proving ground
8. Glowing Cornell dots -- a potential cancer diagnostic tool set for human trials
9. Pixel perfect: Cornell develops a lens-free, pinhead-size camera
10. Understanding the science of solar-based energy: more researchers are better than one
11. Researchers decode viral process that prepares cells for HIV infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... (PRWEB) January 22, 2015 Shimadzu ... new UV-1280 multipurpose UV-visible spectrophotometer. Offering wavelength scanning ... instrument is ideal for applications in a variety ... science. , The user-friendly UV-1280 enables intuitive operation, ...
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart ... 2014 was a record-breaking year across the board for the ... Smart Data Platform and our Smart Data solutions, our customers ... data which led to record growth for the company in ...
(Date:1/22/2015)... California (PRWEB) January 22, 2015 Pipette.com ... Offer to their comprehensive portfolio of Eppendorf products. ... customers to purchase a Centrifuge 5424/5424 R and receive ... of either Eppendorf Research plus or Eppendorf Reference 2 ...
(Date:1/22/2015)... Geneva, Switzerland (PRWEB) January 22, 2015 ... for characterized mammalian Research Cell Banks (RCBs) used for ... generated Research Cell Banks will include Next-Generation Sequencing ... cell’s genetic architecture de-risks biologic manufacturing by ensuring the ...
Breaking Biology Technology:Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Cambridge Semantics Announces Record Results for 2014 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2
... Lisa Marsh Carsten Carstens ,Stratagene , ... expression ,vectors offers unparalleled convenience. The drug-resistance ... without subcloning. Through site-specific ,recombination, hygromycin, puromycin, ... efficiently inserted into the pExchange core vectors. ...
... LipoTAXI transfection reagent: A proven ... ,Stratagene , LipoTAXI ... cells and cells growing in,suspension. In this article, ... the effectiveness of LipoTAXI reagent. Optimizing transfection,conditions is ...
... of 96 PCR products , , Scott ... , The StrataPrep 96 PCR purification ... This kit offers a high-throughput format,for purifying ultra-pure PCR ... PCR purification kit uses the same silica matrix-binding,technology as ...
Cached Biology Technology:Mammalian Expression Vectors with Interchangeable Selectable Markers 2Mammalian Expression Vectors with Interchangeable Selectable Markers 3Mammalian Expression Vectors with Interchangeable Selectable Markers 4Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 2Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 3Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 4Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 5Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 6Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 7High-Throughput System Generates Ultra-Pure PCR Products Suitable for All,Applications 2High-Throughput System Generates Ultra-Pure PCR Products Suitable for All,Applications 3High-Throughput System Generates Ultra-Pure PCR Products Suitable for All,Applications 4High-Throughput System Generates Ultra-Pure PCR Products Suitable for All,Applications 5
(Date:1/22/2015)... Technology Showcase, Hall E -   EyeLock Inc. , ... it will showcase its EyeLock ID technology integrated in a ... Energy,s Oak Ridge National Laboratory (ORNL) at the ... identity authentication technology is being used to validate the driver ...
(Date:1/22/2015)... Washington , January 20, 2015 Investorideas.com, ... tech stocks, releases video from the CES 2015 (Consumer Electronics ... Apollo Robbins . Apollo shows how easily ... smart wallet, a product of NXT-ID, Inc. (NASDAQ: ...
(Date:1/22/2015)... EyeLock, Inc. , a market leader of iris-based identity authentication ... to the new role of Senior Vice President of Mobile ... mobile platforms and wearable solutions for EyeLock,s technologies. Gerber brings ... semiconductor industry to his role at EyeLock, with expertise in ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... researchers have demonstrated a close correlation between the decline ... system and the progression of chronic obstructive pulmonary disease ... decreases the flow of air through the lungs as ... lung tissue samples from COPD patients by scientists at ...
... Media,Group,s, C4ISR Journal will host its 8th Annual C4ISR ... October 16-17, 2008 at the Sheraton,Crystal City Hotel, Arlington, ... C4ISR technology through,various conference sessions including:, ... Sharing for Homeland Defense/Civil Support -- From Net-Centric ...
... MANHATTAN, KAN. -- New findings about the causes of ... genetic. "We now know it,s also in the ... Professor of Diagnostic Medicine and Pathobiology at Kansas State ... ago, Richt said, it was thought that the cattle ...
Cached Biology News:Key component of debilitating lung disease identified 2Annual C4ISR Integrated Conference and Big 25 Awards Banquet 2Annual C4ISR Integrated Conference and Big 25 Awards Banquet 3K-State professor's USDA research shows mad cow disease also caused by genetic mutation 2
S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
Form: Concentrated Applications: ELISA...
RABBIT ANTI HALOPERIDOL...
Form: Ready to use Applications: Western Blot, ELISA...
Biology Products: