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In 2012, Stelara and Briakinumab Will Capture 22 Percent of the Biologics Share in the Moderate to Severe Psoriasis Drug Market
Date:12/16/2009

WALTHAM, Mass., Dec. 16 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, according to responses from surveyed dermatologists, Centocor Ortho Biotech/Janssen-Cilag's Stelara and Abbott's briakinumab (both interleukin inhibitors) will capture 22 percent of the biologics share in 2012 in the drug market for moderate to severe psoriasis. Among these two agents, Stelara will experience greater uptake, capturing nearly three times as much patient share as briakinumab.

The new Physician & Payer Forum report entitled The Next Wave of Psoriasis Biologics: Physician and Payer Perspectives on Novel Interleukin Inhibitors finds that, among the currently-available TNF-alpha inhibitors, Amgen/Pfizer/Takeda's Enbrel--the most-prescribed biologic in psoriasis--will lose the greatest percentage of sales as a result of Stelara's uptake. By the end of 2012, surveyed physicians expect to use Stelara in 16 percent of biologics-treated patients with moderate to severe psoriasis. Additionally, Abbott/Eisai's TNF-alpha inhibitor Humira will also lose substantial market share to Stelara. However, the report finds that other biologics such as Centocor Ortho Biotech/Merck/Mitsubishi Tanabe's Remicade (a TNF-alpha inhibitor) and Astellas's Amevive (a T-cell modulator) are expected to preserve their limited market share, owing to their status as niche therapies.

"Currently, biologic treatment for psoriasis is overwhelmingly dominated by Enbrel, Humira and Remicade as these agents have proved effective and, after years of marketing, physicians' concerns about the long-term safety of these drugs have eased somewhat," said Decision Resources Analyst Joanna Kim, M.Ed. "However, the landscape for biologic therapies in psoriasis experienced a noteworthy shift when Genentech/Merck Serono's T-cell modulator Raptiva was withdrawn from the market
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SOURCE Decision Resources
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