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Improved Cord Blood Processing Research on BioLife Solutions CryoStor® Published in TRANSFUSION
Date:2/17/2012

BOTHELL, Wash., Feb. 17, 2012 /PRNewswire/ -- BioLife Solutions, Inc. (OTCBB: BLFS), a leading developer, manufacturer and marketer of proprietary clinical grade hypothermic storage and cryopreservation freeze media for cells and tissues, today announced that TRANSFUSION, the foremost publication in the world for new information regarding transfusion medicine, has published a peer-reviewed journal article reporting positive results of collaborative research on CryoStor®, BioLife's serum-free, protein-free cryopreservation freeze media.  Study conclusions include the following:

  • The use of pre-formulated CryoStor reduced overall processing time, compared to an in-house formulation, which is made on demand each day
  • CryoStor resulted in improved recovery of viable total nucleated cells (TNC) and CD34+ cells, a type of pluripotent stem cell found in umbilical cord blood
  • The final concentration of DMSO, the main cryoprotectant in freeze media formulations, was reduced to 5% in CryoStor, compared to 10% in the in-house formulation

    • (Logo:  http://photos.prnewswire.com/prnh/20090814/BIOLIFELOGO)

    The article, titled Cryopreservation of Umbilical Cord Blood with a Novel Freezing Solution that Mimics Intracellular Ionic Composition, includes comparative and correlative data on the rate of addition of freeze media to cells, exothermic temperature excursions during mixing, and post-freeze/thaw cell viability and recovery. 

    The research, conducted at the Puget Sound Blood Center in Seattle, focused on comparing BioLife's pre-formulated GMP grade

    SOURCE BioLife Solutions, Inc.
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