Navigation Links
Implantable slimming aid
Date:11/26/2013

Humankind has a weight problem and not only in the industrialised nations, either: the growing prosperity in many Asian or Latin American countries goes hand in hand with a way of life that quite literally has hefty consequences. Ac-cording to the WHO, over half the population in many industrialised nations is overweight, one in three people extremely so. Not only is high-calorie and fatty food a lifetime on the hips, backside and stomach; it also leaves traces in the blood, where various fats ingested via food circulate. Increased blood-fat values are also regarded as a risk factor for heart attacks and strokes.

Genetic regulatory circuit monitors blood fat

The research group headed by ETH-Zurich professor Martin Fussenegger from the Department of Biosystems Science and Engineering in Basel has now de-veloped an early warning system and treatment: an implantable genetic circuit mainly composed of human gene components. On the one hand, it constantly monitors the circulating fat levels in the blood. On the other hand, it has a feed-back function and forms a messenger substance in response to excessively high blood-fat levels that conveys a sense of satiety to the body.

In order to construct this highly complex regulatory circuit, the biotechnologists skilfully combined different genes that produce particular proteins and reaction steps. They implanted the construct in human cells, which they then inserted into tiny capsules.

The researchers studied obese mice that had been fed fatty food. After the cap-sules with the gene regulatory circuit had been implanted in the animals and intervened due to the excessive levels, the obese mice stopped eating and their bodyweight dropped noticeably as a result. As the blood-fat levels also returned to normal, the regulatory circuit stopped producing the satiety signal.

"The mice lost weight although we kept giving them as much high-calorie food as they could eat," stresse
'/>"/>

Contact: Martin Fussenegger
martin.fussenegger@bsse.ethz.ch
41-613-873-160
ETH Zurich
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Allegheny General Hospital Cardiovascular Team Introduces New MRI Capability for Patients with Pacemakers, Implantable Defibrillators
2. Global Implantable Drug Delivery Devices Market - New Industry Research Report Published by Transparency Market Research
3. U.S. Implantable Medical Devices Market is Expected to Reach USD 73.9 Billion by 2018: Transparency Market Research
4. First successful human results achieved: Implantable wireless microchip drug delivery device
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Implantable slimming aid
(Date:12/24/2014)... (PRWEB) December 23, 2014 ... series is designed to introduce cutting edge ... users and partners of platform upgrades. This ... benefits; empowering users in their quest to ... tools. , According to SoundConnect’s Marketing Manager, ...
(Date:12/24/2014)... Texas (PRWEB) December 23, 2014 ... methyl mercaptan such as its definition, classification, ... presents product specification, manufacturing process, and product ... technology and applications. The analysis also covers ... marketing channels, industry development trend and proposals. ...
(Date:12/24/2014)... 2014 Pipette.com announces their Holiday ... can submit their #HolidayInTheLab pictures for a chance to ... , For those struggling to think of a holiday ... in the Lab Contest provides the ideal holiday presents. ... to send pictures of their chemistree, holiday sweaters, as ...
(Date:12/24/2014)... , December 23, 2014 ... Algeria , out today and available for free download ... actors driving change and growth in the sector today. ... scored notable successes has been in developing a homegrown pharmaceutical ... percent local production still remains some way off. A cursory ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3
... thing with IT shops right now. It's the new magic ... word and the music swells. Then we'll go skipping off ... happy customers. Yes, I was touting partnership just last week ... hard work. Partnership is the right relationship answer only if ...
... announced Wednesday it has been awarded a contract ... management hardware for a U.S. Department of Energy ... million project will develop, manufacture and demonstrate a mine ... metal-hydride storage and refueling hardware. , ,The project was ...
... Left to right: Professor James Dumesic, graduate students Steven ... researcher Won Bae Kim. Source: UW-Madison. MADISON - ... technical barrier to the efficient operation of fuel cells. ... of Wisconsin-Madison have not only cleared that barrier - ...
Cached Biology Technology:Blooming partnerships 2Blooming partnerships 3Blooming partnerships 4Modine Manufacturing to contribute to DOE's fuel-cell vehicle 2UW engineers clear bottleneck in hydrogen production 2
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the ... APAC Region 2015-2019"  report to their offering. ... market is advances in technology. With continuous advances ... solutions to the latest standard that meets the ...
(Date:12/11/2014)... , Dec. 10, 2014  That blood pressure plays ... a while. Hypertension – the medical term for high blood ... early 1800s, and the inflatable cuff that,s used in measuring ... however, mean there,s nothing new about hypertension, its triggers and ... beliefs about the condition and the best ways to treat ...
(Date:12/10/2014)... 2014 You,ve been here before: you desperately need ... your password, site key or the answer to your secret ... teacher? Today, Hoyos Labs , a ... will finally put an end to the frustration that comes ... . 1U leverages a user,s smartphone to acquire his or ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... 6, 2011 Ceelox, Inc. (OTCBB: CELO) announced today ... which operates on computers running the Windows 7 Operating ... their authentication approach to leverage the recent capability of ... (WBF) provides support for fingerprint biometric devices through a ...
... an alternative to drugs for the prevention of esophageal ... Annual Meeting 2011, held here April 2-6. ... eating strawberries is safe and easy to consume. In ... histological grade of precancerous lesions and reduce cancer-related molecular ...
... That,s the agonizing choice some birds face, according to ... by Guelph researchers discovered that for some male birds traveling ... attracting a female when they return home. Alice Boyle, a ... Chris Guglielmo, a biologist at the University of Western Ontario, ...
Cached Biology News:Ceelox Offers Beta Release of Ceelox ID 7 for Personal Computers 2Strawberries may slow precancerous growth in esophagus 2Birds must choose between mating, migrating, study finds 2
Mouse monoclonal [M2II-12] to MRP2 ( Abpromise for all tested applications). entrezGeneID: 1244 SwissProtID: Q92887...
Mouse monoclonal antibody to ANAPC2 - anaphase promoting complex subunit 2...
... The MAX POWER 500V Programmable ... operate instruments which can handle virtually ... to high current blotting. It is ... text displays. The MAX POWER Programmable ...
The Programmable MP-3500P-F Power Supply can be applied for any Microfluidic application....
Biology Products: