Navigation Links
Immunomic Therapeutics Receives IND Authorization for Phase I Study of JRC-LAMP-Vax Vaccine to Treat Japanese Red Cedar (Sugi) Allergy
Date:5/3/2012

LANCASTER, Pa. and ROCKVILLE, Md., May 3, 2012 /PRNewswire/ -- Immunomic Therapeutics, Inc., ("ITI," Lancaster, PA) a privately-held biotechnology company with laboratories in Rockville, MD, announced that the U.S. Food and Drug Administration (FDA) has completed its review of the Investigational New Drug Application ("IND") filed for the allergy immunotherapy, JRC- LAMP-vax.  On April 12th, the FDA notified ITI that there will be no clinical hold and that ITI may now proceed with its clinical trial in June for JRC-LAMP-vax in Atlanta with subjects sensitive to Japanese Red Cedar pollen.

JRC-LAMP-Vax is a plasmid-based DNA vaccine that will be studied for the treatment of patients with rhino-conjunctivitis (runny nose) symptoms caused by allergic reaction to Japanese red cedar pollen. Almost 45% of the Japanese people are allergic to Japanese red cedar pollen. In North America, there is allergic rhinitis to mountain cedar pollen, which is 80% cross-reactive with Japanese red cedar pollen allergen.  ITI intends to partner with a Japanese pharmaceutical company for studies in Japan and will seek FDA approval of the vaccine in the US.

ITI provided FDA with animal studies of JRC-LAMP-Vax, showing no alteration of the routine clinical pathology, body weight, food consumption, temperature, ophthalmology, dermal irritation or the histopathology of any tissue examined microscopically. Overall, JRC-LAMP-Vax caused no abnormal safety issues in bio-distribution and toxicology studies in animals. This data was consistent with other reported animal and human studies of components of its vaccine.

Animal safety studies and human clinical studies have documented that LAMP DNA vaccine induces a protective antibody immune response consistent with a preferential MHC-II immune system presentation induced by the LAMP component. LAMP-based vaccines hold potential
'/>"/>

SOURCE Immunomic Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Silence Therapeutics Partner, Quark Pharmaceuticals, Extends its Agreement With Pfizer to Develop one of Its Compounds Containing Silences AtuRNAi in a New Indication
2. Regulus Therapeutics Appoints Bruce Carter to its Board of Directors
3. Cell Therapeutics, Inc. (CTI) Reports First Quarter Financial Results and Milestones
4. Echo Therapeutics to Present Positive Clinical Trial Results at the 72nd Scientific Sessions of the American Diabetes Association
5. Islet Sciences Announces DiaKine Therapeutics Novel Diabetes, Atherosclerosis Drugs Receives European Patent Protection
6. Tarsa Therapeutics Completes $28 Million Series B Financing to Advance OSTORA™ Oral Calcitonin
7. Halozyme Therapeutics to Present at Two Upcoming Investor Conferences in March
8. Karyopharm Therapeutics Announces Multiple Presentations on Selective Inhibitors of Nuclear Export (SINE) in Solid and Hematologic Malignancy Models and Spontaneous Canine Cancers at the American Association of Cancer Research (AACR) Meeting
9. Incline Therapeutics to Present at the Cowen and Company 32nd Annual Health Care Conference
10. Foundation for Angelman Syndrome Therapeutics (FAST) Funds Human Clinical Trial
11. Silence Therapeutics Announces Board Changes and Appointment of New Chief Executive Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched ... tinnitus. Patients listen to sound therapy that is tailor-made ... weeks to months, their tinnitus volume decreases. , AudioNotch has ... and Notched White Noise. Now, AudioNotch is pleased to announce ...
(Date:1/14/2014)... a leading provider of strategic communications services to corporations and organizations ... the United States and Europe ... is returning to the firm,s Washington, D.C. ... than two years of service as Associate Commissioner for the Office ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
(Date:1/14/2014)... USA, and Cardiff, UK (PRWEB) January 13, 2014 ... technology development leader with more than 20 years in ... for optics and photonics . Hainsey will serve as ... delighted to have Dr. Hainsey join SPIE as our ...
Breaking Biology Technology:Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2
... Report the Use of Haptoglobin Typing,to Predict Cardiovascular ... MONTVALE, N.J., Nov. 10 Synvista,Therapeutics, Inc. ... Annual Scientific,Sessions of the American Heart Association, underway ... determine haptoglobin (Hp) genotype utilizing,intellectual property licensed from ...
... Nov. 10 SenesTech, Inc. has launched,the regulatory ... the first,ContraPest(R) product with the government of Australia. ... rice field rat species, registration,of ContraPest(R) bait will ... management product to the agricultural ministries of Southeast,Asia. ...
... with more than $500 million in ... cash - Conference ... ... ISIS ) today announced its financial results,for the third quarter ended September 30, 2008. Isis, ...
Cached Biology Technology:Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association 2Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association 3Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association 4Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association 5SenesTech, Inc. Commences Product Registration Process With Australian Government 2Isis Reports Financial Results and Highlights for Third Quarter of 2008 2Isis Reports Financial Results and Highlights for Third Quarter of 2008 3Isis Reports Financial Results and Highlights for Third Quarter of 2008 4Isis Reports Financial Results and Highlights for Third Quarter of 2008 5Isis Reports Financial Results and Highlights for Third Quarter of 2008 6Isis Reports Financial Results and Highlights for Third Quarter of 2008 7Isis Reports Financial Results and Highlights for Third Quarter of 2008 8Isis Reports Financial Results and Highlights for Third Quarter of 2008 9Isis Reports Financial Results and Highlights for Third Quarter of 2008 10Isis Reports Financial Results and Highlights for Third Quarter of 2008 11Isis Reports Financial Results and Highlights for Third Quarter of 2008 12Isis Reports Financial Results and Highlights for Third Quarter of 2008 13Isis Reports Financial Results and Highlights for Third Quarter of 2008 14Isis Reports Financial Results and Highlights for Third Quarter of 2008 15
(Date:4/17/2014)... Current Biology on April 17 have discovered ... Brazilian insects, which represent four distinct but related species ... example of an animal with sex-reversed genitalia. , ... animals, Neotrogla is the only example in ... Yoshizawa from Hokkaido University in Japan. , During copulation, ...
(Date:4/17/2014)... is the process whereby the genetic information of ... as proteins, which have numerous different functions in ... important intermediary during gene expression, by relating the ... involved in manufacturing proteins. , By examining ... present in an organism at a given time, ...
(Date:4/17/2014)... Pine forests are chock full of wild animals and ... populations of fungi are churning away in the soil, ... , Despite the vital role these fungi play in ... A Stanford-led team of scientists has generated a genetic ... North America. The work was published this week in ...
Breaking Biology News(10 mins):In sex-reversed cave insects, females have the penises 2Rapid and accurate mRNA detection in plant tissues 2Stanford biologists help solve fungal mysteries 2Stanford biologists help solve fungal mysteries 3
... Southwestern Medical Center challenge one of the established views ... Every time we move, feel emotions, think or remember, ... messages to one another via chemical signals called neurotransmitters. ... sequester neurotransmitters and release them when needed into the ...
... all in the packaging. How nature wraps and tags genes ... from Harvard and the Massachusetts Institute of Technology (M.I.T.). They ... protein structure that surrounds the human genome. , Their findings ... switched on during development of the human body and in ...
... older are as,inevitable and obvious as “going gray,?yet ... of this usually unwelcome transformation.,In a report posted ... Science,researchers from Dana-Farber Cancer Institute and Children’s Hospital,Boston ... graying hair while,investigating the origins of malignant melanoma, ...
Cached Biology News:New research questions basic tenet of neuron function 2Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease 2Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease 3Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones. 2Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones. 3
Anti-MT3-MMP Membrane-Type Metalloproteinase-3; propeptide domain; rabbit host...
Rabbit polyclonal to Methionine Aminopeptidase 2 ( Abpromise for all tested applications). entrezGeneID: 10988 SwissProtID: P50579...
Mouse monoclonal [TU-20] to beta III Tubulin (FITC) ( Abpromise for all tested applications). entrezGeneID: 10381 SwissProtID: Q13509...
Chlamydia pneumoniae (TWAR)...
Biology Products: