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ImaRx Therapeutics Reports Business Update and Financial Results for Fourth Quarter and Full Year 2007
Date:3/31/2008

tions necessary to support the extension of expiration dating for urokinase inventory to between July and September of 2009. The Company submitted for and the FDA approved the release of three lots of urokinase during the first quarter of 2008 under the new Kinlytic trade name. The Company believes this labeled inventory will be sufficient to meet market demand through September 2009. ImaRx intends to continue its stability program to evaluate the potential for further expiration extensions beyond September 2009 for unlabeled vials of urokinase inventory.

Bradford A. Zakes stated, "The extension of the expiration dating and FDA approval of our recent requests for lot release represent a significant accomplishment for ImaRx, by allowing us to generate additional value from the continued sale of our urokinase inventory well into 2009. We remain confident that the stability profile of our urokinase inventory will enable us to achieve future expiration date extensions as we market the balance of our existing unlabeled vials of urokinase."

In January 2008 ImaRx signed a Letter of Intent with Microbix Biosystems Inc. (TSE: MBX) to manufacture and continue selling urokinase beyond the existing inventory. Closing of the transaction is dependent upon the satisfactory completion of due diligence and Microbix securing adequate financing to transfer the manufacturing process. A new supply of urokinase would allow ImaRx to continue to serve its current customers. It also would provide the opportunity to expand sales to additional vascular physicians and acute care institutions and to explore clinical development of urokinase for additional vascular indications.

In connection with the urokinase acquisition in April 2006, the Company issued a $15.0 million non-recourse promissory note to Abbott that matures on March 31, 2008. The outstanding balance of the note plus accrued interest, net of funds in escrow, is $10.8 million. The Company has reached a tentative
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SOURCE ImaRx Therapeutics, Inc.
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