Navigation Links
Identifying targets of autoantibodies
Date:11/25/2013

Patients with the autoimmune disease systemic lupus erythematosus (SLE) produce autoantibodies that target can cause damage to multiple organ systems. The host factors that are targeted by autoantibodies produced by SLE patients are not fully understood.

In this issue of the Journal of Clinical Investigation, Jordan Price and colleagues at Stanford University developed a microarray to identify cytokines, chemokines, and other circulating proteins as potential targets of the autoantibodies produced by SLE patients. The authors identified several autoantibody targets, and determined that SLE patients with high levels of autoantibodies directed against the B cell activating factor (BAFF) had more severe SLE-associated symptoms.

In an accompanying commentary, Maureen Su of the University of North Carolina and Stephanie Sarantopoulos of Duke University discuss how identification of autoantibody targets produced by patients with autoimmune disorders will be informative for diagnosis and therapeutic strategy development.


'/>"/>

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Identifying Opportunities, Growth and Generating Returns for Indian Healthcare Businesses
2. Important breakthrough in identifying effect of epilepsy treatment
3. Genelux, a Leader in the Emerging Oncolytic Virotherapy Field, Receives Significant Industry Honor from Elsevier Business Intelligence, Identifying GL-ONC1 as One of 2013s Top Oncology Projects to Watch
4. Tarsa Therapeutics Targets 2012 NDA Submission for its OSTORA™ Oral Calcitonin
5. Metamark Genetics Signs Collaboration Agreement on Novel Therapeutic Targets with Janssen Biotech
6. X-BODY BioSciences to Present Novel Methods of Selecting for Antibodies Against Targets on Live Cells at CHIs Protein Engineering Summit
7. Butamax Early Adopters Group surpasses capacity targets with addition of Big River; Membership represents 11 production facilities and nearly 900 million gallons of ethanol capacity
8. Kenrico Announces Records of Patents for 2012 and Financial Targets for 2013
9. Transcreener Assays Highlighted for Challenging Microbial, Cancer and Epigenetic Drug Targets at SLAS 2013
10. Oxford BioTherapeutics and Boehringer Ingelheim Enter Collaboration to Discover Novel Antibody Targets in Cancer
11. Personal Genome Diagnostics And Blueprint Medicines Form Collaboration to Identify Novel Kinase Targets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... MA and Azusa, CA (PRWEB) , ... December ... ... provider of distributed wastewater treatment and resource recovery solutions for industrial facilities, today ... Company , will be the first to use Cambrian’s novel water-energy purchase agreement ...
(Date:12/6/2016)... The American Botanical Council (ABC) recognizes ... ( Arnica montana ) through ABC,s Adopt-an-Herb program. ... database, a comprehensive, interactive online tool that ... data on the uses and health effects of ... a wellness company with healing arts centers, skin ...
(Date:12/6/2016)... and Albany, NY (PRWEB) , ... December 06, ... ... control system integrator of custom industrial automation and IT solutions, today announced the ... Superior Controls has reliably delivered professionally executed automation and control systems integration services ...
(Date:12/6/2016)... 2016 Zimmer Biomet Holdings, Inc. (NYSE ... pricing terms of its previously-announced cash tender offers ... price (excluding accrued and unpaid interest to, but ... fees and expenses related to the Offers) (the ... in the table below (collectively, the "Notes"). The ...
Breaking Biology Technology:
(Date:12/6/2016)... -- Valencell , the leading innovator in performance ... third consecutive year of triple digit growth for its ... a 360 percent increase in companies who have acquired ... by sales of its wrist and ear Benchmark™ sensor ... for hearables for fitness and healthcare applications. ...
(Date:12/2/2016)... PUNE, India , December 1, 2016 /PRNewswire/ ... Market by Authentication type (Fingerprint, Voice), Future Technology (Iris ... Vehicle), and Region - Global Forecast to 2021", ... be USD 442.7 Million in 2016, and is ... 2021, at a CAGR of 14.06%. ...
(Date:11/30/2016)... CHICAGO , Nov. 30, 2016  higi ... a new partnership initiative targeting national brands, industry ... and reward their respective audiences for taking steps ... Since its inception in 2012, higi has built ... US, impacting over 38 million people who have ...
Breaking Biology News(10 mins):