Navigation Links
Idenix Pharmaceuticals Reports Data From Three Hepatitis C Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver
Date:4/23/2009

vity, with tight binding to the HCV protease and no activity observed against eight human cellular proteases. IDX316 retained activity against common mutations in NS3 and exhibited enhanced activity when combined with standard-of-care agents or other Idenix compounds in development (IDX184 and IDX375). Favorable PK profiles in rodent and non-human primate species suggest the potential for once- or twice-daily dosing in humans (half-life of 4.0-5.2 h; bioavailability of ~20%).

IDX375 Non-Nucleoside Polymerase Inhibitor

The preclinical pharmacokinetic and toxicology profile of IDX375 was also presented at EASL. Data support once- or twice-daily dosing in HCV-infected patients based on favorable bioavailability and plasma drug exposure levels in animal studies. IDX375 showed limited metabolism and no cytotoxicity when incubated with mouse, rat, monkey or human hepatocytes. IDX375 demonstrated no adverse effects in monkeys given daily oral doses of 10 or 100 mg/kg for 7 days.

About Idenix

Idenix Pharmaceuticals, Inc., headquartered in Cambridge, Massachusetts, is a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases. Idenix's current focus is on the treatment of infections caused by hepatitis C virus. For further information about Idenix, please refer to www.idenix.com.

Forward-looking Statements

This press release contains "forward-looking statements" within the meaning of The Private Securities Litigation Reform Act of 1995. Such forward-looking statements can be identified by the use of forward-looking terminology such as "may," "plans," "anticipates," "will," or similar expressions, or by expres
'/>"/>

SOURCE Idenix Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Idenix Pharmaceuticals Restructures to Concentrate Efforts on HCV and HIV Programs
2. Idenix to Host Conference Call Discussing Third Quarter 2007 Financial Results
3. Idenix Pharmaceuticals to Present at BIO CEO & Investor Conference
4. Idenix to Host Conference Call Discussing Fourth Quarter 2007 Financial Results
5. Idenix Announces Data Presentations at the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL)
6. Idenix Pharmaceuticals to Present at the Morgan Stanley Global Healthcare Unplugged Conference
7. Idenix Pharmaceuticals to Present at the Rodman & Renshaw 5th Annual Global Healthcare Conference
8. Idenix Pharmaceuticals to Present at the Seventh Annual Needham and Company, LLC Biotechnology and Medical Technology Conference
9. Idenix Pharmaceuticals Reports Second Quarter and Six Month Financial Results
10. Idenix Pharmaceuticals to Present at the Bank of America 2008 Specialty Pharmaceuticals Conference
11. Idenix to Host Conference Call Discussing Third Quarter 2008 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... NJ (PRWEB) August 21, 2014 ... personal selling optimization technology and services for Life ... of “Grading Pharma’s Use of New Commercial Sales ... Measurement & Analytics. , The article examines some ... yield that are being tested in the pharmaceutical ...
(Date:8/21/2014)... Gallus BioPharmaceuticals , LLC, ... manufacturing organization (CMO) announced today that it has ... company focused on the development of innovative approaches ... anti-prostate specific membrane antigen (PSMA) monoclonal antibody used ... the agreement the antibody will be produced in ...
(Date:8/21/2014)... On Wednesday of last week RENU 28, the ... molecules, became available for purchase in Australia and New Zealand, ... RENU 28 works is, if you think about the definition ... of cellular renewal within your body. If you think about ... of cellular renewal. What RENU 28 does is it works ...
(Date:8/20/2014)... of patented university inventions licensed to biotechnology firms ... commercialization. To open these roadblocks, the researchers suggest ... the discovery stage could lead to faster commercialization ... derived from discoveries made in university laboratories and ... during clinical trials, which have a high failure ...
Breaking Biology Technology:Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 3RENU 28 Skin Care Now Available in Australia and New Zealand 2Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3
... PharmaVentures announced today that it was delighted ... US and Canada as Merck & Co) to secure its ... Nottingham and Roslin BioCentre, for the former MSD research facility ... working between MSD, the Scottish Life Sciences community and the ...
... 17, 2012  Cepheid (Nasdaq: CPHD ) today ... the position of Senior Vice President, Human Resources, effective ... Cepheid from Verigy, Inc., a wholly owned subsidiary of ... Vice President of Human Resources.  Prior to Verigy, Mr. ...
... from a Nobel Laureate. Find out how major discoveries ... policy, education, and research in other countries. The iBioSeminars ... online, on-demand, and for free. iBioSeminars ... biology seminars given by the world,s leading researchers. The ...
Cached Biology Technology:PharmaVentures Helps Secure Investor for Former MSD Research Site 2Cepheid Welcomes Senior Vice President of Human Resources 2iBioSeminars and iBioMagazine: Free, Online Biology Seminars and Short Talks by Leading Scientists 2
(Date:8/21/2014)... Athens, Ga. An international team of scientists including researchers ... Brassica napus commonly known as canolain the journal ... of the plant, which is used widely in farming and ... and its native Europe, but the winter crop is increasingly ... for its naturally low levels of saturated fat and rich ...
(Date:8/21/2014)... A new study of American singles found that ... the highest orgasm rates. On average, men experience ... sexual orientation making little difference. For women, however, ... experience orgasm 62.9 percent of the time during ... pattern varies with women,s sexual orientation, with lesbian ...
(Date:8/21/2014)... darkness use a previously unknown process for harvesting energy ... by a Penn State University scientist has discovered. The ... improving plant growth, harvesting energy from the Sun, and ... Erie and other lakes worldwide. A paper describing the ... Express edition of the journal Science on ...
Breaking Biology News(10 mins):Canola genome sequence reveals evolutionary 'love triangle' 2Orgasm rates for single women less predictable than men's, vary by sexual orientation 2Orgasm rates for single women less predictable than men's, vary by sexual orientation 3Orgasm rates for single women less predictable than men's, vary by sexual orientation 4Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3
... findings about life in the heart of Yellowstone National ... years of Montana State University research. The book ... Sixteen Years of Integrated Field Studies" covers many of ... attention, said editor and MSU ecologist Robert A. Garrott. ...
... role in the disparity between the numbers of African ... the disease. A study by researchers at the Johns ... disparity was substantially reduced when comparing groups of African ... The results are published in the November 2008 print ...
... | Union County New Mexico is a landscape of striking ... cone volcanoes and mesas preserved by basalt, part of the ... is the youngest volcano in the field. The cone rises ... m above sea level. The base of the volcano is ...
Cached Biology News:New book covers 16 years of MSU research in Yellowstone 2New book covers 16 years of MSU research in Yellowstone 3Hypertension disparity linked to environment 2Scientists map soils on an extinct American volcano 2
HLA-DRbeta (DA2)...
... to Cytokeratin 5 / 6 Cytokeratin ... weight, basic type of cytokeratin expressed in ... layers of stratified epithelia as well as ... cells and mesothelioma. Cytokeratin 6 (56 kD) ...
...
Aldolase A (N-15)...
Biology Products: