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ISTO Technologies, Inc., Completes Enrollment in Phase I NuQu Clinical Trial
Date:10/5/2010

nas Medical Center, and Dr. Kenneth Pettine, co-founder of the Spine Institute and an international leader in non-fusion spine research of Loveland, Colorado. "Disc nucleus regeneration and repair represent an important area of ongoing spine research. It offers the promise of a minimally invasive intervention that treats a patient's symptoms while potentially restoring function to the disc," said Dr. Coric. "This technology offers the promise of regeneration, repair and restoration of function for a very large patient population that suffers from chronic back pain," added Dr. Coric.

Dr. Pettine commented, "A tissue engineering approach and, in particular, a cell-based therapy to treat degenerative discs represents a new renaissance in spine treatment. This technology has enormous potential for filling a significant unmet medical need and may offer an important additional treatment option for our patients."

Discogenic back pain impacts about 4 million patients annually in the United States, with an estimated 500,000 individuals not responding to conservative treatments such as bed rest, non-steroidal anti-inflammatory pain medication and physical therapy. In addition to the physical pain endured by those afflicted by chronic back pain, these ailments add significant economic and social costs to the healthcare system and the overall economy. According to a recent study published in the August 15, 2010 issue of Spine and conducted by Annette Becker, M.D., of the University of Marburg in Germany and her colleagues, the costs (direct and indirect) of caring for patients with chronic low back pain were about twice that required to care for acutely ill patients.  

About ISTO Technologies ISTO is a privately-held orthobiologics company with a platform cell-based technology for cartilage regeneration. The company is dedicated to improving patient quality of life through the development of proprietary products for spinal and knee therapies
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SOURCE ISTO Technologies, Inc.
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