Navigation Links
Hutchinson Center Receives $7.6 Million Federal Grant to Study How Genetic Variations Influence Risk of Common Diseases
Date:7/17/2008

tic variants influence disease. "We hope to learn more about the mechanisms by looking at the associations between these genetic variations and intermediate biomarkers of disease, such as cholesterol levels as a marker for heart disease and bone density as a marker for hip fractures," she said.

To this end, the researchers will aim to genotype blood samples from 58,000 WHI study participants to investigate up to 100 known disease-specific genetic variants.

"Information generated from this study will be critical to determine the health impact of any given genetic variant and to prioritize them for intervention studies aimed to reduce their associated risk," Kooperberg said. "These findings may also provide valuable insights into disease pathways and mechanisms, and identify targets for disease screening, prevention and treatment."

The Hutchinson Center's Public Health Sciences Division houses the Clinical Coordinating Center for the Women's Health Initiative, one of the most definitive, far-reaching studies of postmenopausal women's health ever undertaken in the United States. Enrollment began in 1993 and participants will be followed at least until 2010. The study examines the prevalence and risk factors for a number of diseases common in aging women, as well as the effects of various interventions, from low-fat diets and hormone therapy to calcium and vitamin D supplementation.

"We are extremely grateful for the study participants who have provided a wealth of biological data that will permit us to link genetic variants to relevant intermediate biomarkers that will potentially provide important clues to the biological basis of the disease," Kooperberg said.

Also collaborating on the project, in addition Kooperberg, Peters and colleagues from the WHI Clinical Coordinating Center, are investigators from the University of Arizona Cancer Center, Ohio State University and the University of Pittsburgh.

For more information about
'/>"/>

SOURCE Fred Hutchinson Cancer Research Center
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Fred Hutchinson Cancer Research Center and NSB POSTECH, Inc. to Collaborate on Development of New Class of Proteomic Microarrays
2. University of Miami Miller School of Medicine Becomes a GeneGo Center of Excellence
3. N.C. Biotech Center Launches Larger Loans
4. NorthPoint Domain and Boston Medical Center Partner to Apply Advanced Patient Engagement Instruments to Pioneering Cardiac Robotic Surgery Program
5. Yale Keck Microarray Center Becomes a GeneGo Center of Excellence
6. CET Life Sciences Center Welcomes Belmont University School of Pharmacy as New Tenant
7. N.C. Biotechnology Center Launches Industrial Fellowship Program
8. Worldwide Center for Adult Stem Cell Education LLC Changes Name to The Repair Stem Cell Institute LLC
9. U.S. Commerce Secretary Gutierrez Cuts Ribbon on MaxWell Biocorporations New Pharmaceutical Development Center and Quality Control Laboratory in Ukraine
10. TCN e-Systems Offers Trial Sponsors Solutions for Creating In-House Center of Excellence in Patient Recruitment
11. Spine Surgeons at Pine Creek Medical Center Take the Lead in Utilizing Stem Cell Technologies in Surgical Procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... (PRWEB) January 14, 2014 In recent ... motives and methods in product development and promotion has ... industry. This mistrust, fueled by concerns about the insidious ... by reports of spectacular fines to the world’s biggest ...
(Date:1/14/2014)... January 14, 2014 Global Record ... innovative information technology solutions for patients, physicians, the ... stakeholders, announced today the signing of a three-year ... and Drug Administration (FDA). This initiative is ...
(Date:1/14/2014)... Bellingham, Washington, USA, and Cardiff, UK (PRWEB) January 13, ... and photonics technology development leader with more than 20 ... international society for optics and photonics . Hainsey will ... “We are delighted to have Dr. Hainsey join SPIE ...
(Date:1/14/2014)... 2014 During the 1600’s through the 1800’s ... Doctor’s Plague.” In this time period, doctors did not know ... times, to the death of vulnerable patients. In the same ... they may be unwittingly transmitting herpes viruses to their patients. ...
Breaking Biology Technology:The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... Healthcare Quality has been chosen to lead an effort ... participation will not necessarily be based on the level of ... pilot project to develop a practical method of collecting performance ... that is useful to both physicians and consumers. While the ...
... keynote at the Fusion2006 CEO-CIO Symposium , WTN caught up ... and when it's a good idea. Read part one . ... of distributing the risk of development to other organizations. But doesn't ... , Koulopoulos Koulopoulos: Probably the second most ...
... more than 100 people have been infected with the H5N1 ... the fact that the virus does not spread easily from ... biomedical puzzle. , ,Now, a study of cells in the ... cells of the system that makes it difficult for the ...
Cached Biology Technology:Healthcare quality initiative shuns high-tech for now 2IT outsourcing according to Tom Koulopoulos, part 2 2IT outsourcing according to Tom Koulopoulos, part 2 3IT outsourcing according to Tom Koulopoulos, part 2 4UW shows why avian flu hasn't spread among humans yet 2UW shows why avian flu hasn't spread among humans yet 3
(Date:4/17/2014)... full of wild animals and plant life, but there,s ... churning away in the soil, decomposing organic matter and ... role these fungi play in ecological systems, their identities ... scientists has generated a genetic map of more than ... was published this week in the Proceedings of ...
(Date:4/17/2014)... International researchers, led by the Australian National University ... sea-level changes and deep-sea temperature variability over the ... scientists better understand the climate surrounding ice ages ... help determine the relationship between carbon dioxide levels, ... ANU, the University of Southampton (UoS) and the ...
(Date:4/17/2014)... about domestication derive from Charles Darwin, whose ideas ... practices during the 19th century, a period when ... It is from Darwin that we inherit the ... from wild species and total human control over ... in this industrial setting has been applied too ...
Breaking Biology News(10 mins):Stanford biologists help solve fungal mysteries 2Stanford biologists help solve fungal mysteries 3Ancient sea-levels give new clues on ice ages 2The story of animal domestication retold 2The story of animal domestication retold 3The story of animal domestication retold 4
... the MUHC have discovered a gene that controls the ... a gene has been discovered for this disease. The ... Academy of Science (PNAS) this week provides a new ... and may contribute to public health efforts aimed at ...
... A major cause of hospital-acquired infections can persist ... found in healthcare settings, including bed linens, computer ... presented today at the 105th General Meeting of ... aureus (MRSA) is a major cause of hospital-acquired ...
... A major cause of hospital-acquired infections can persist ... found in healthcare settings, including bed linens, computer ... presented today at the 105th General Meeting of ... aureus (MRSA) is a major cause of hospital-acquired ...
Cached Biology News:Scientists discover gene that controls speed of tuberculosis development 2
Cyno macaque plasma and serum - various quantities available...
3'-O-Methylguanosine 5'-Triphosphate, Sodium, 1 umol. Category: Nucleotides & Enzymes & Biochemicals, Nucleotides, Additional Nucleotide Products....
EPH electrode, cathode, 1. Category: Electrophoresis Systems & Standards & Reagents, IEF & SDS-PAGE & 2-D Electrophoresis, Multiphor II Kits & Components and Accessories....
Rat Normal Multiple Tissue Array 1 slide...
Biology Products: