Navigation Links
Hutchinson Center Receives $7.6 Million Federal Grant to Study How Genetic Variations Influence Risk of Common Diseases
Date:7/17/2008

tic variants influence disease. "We hope to learn more about the mechanisms by looking at the associations between these genetic variations and intermediate biomarkers of disease, such as cholesterol levels as a marker for heart disease and bone density as a marker for hip fractures," she said.

To this end, the researchers will aim to genotype blood samples from 58,000 WHI study participants to investigate up to 100 known disease-specific genetic variants.

"Information generated from this study will be critical to determine the health impact of any given genetic variant and to prioritize them for intervention studies aimed to reduce their associated risk," Kooperberg said. "These findings may also provide valuable insights into disease pathways and mechanisms, and identify targets for disease screening, prevention and treatment."

The Hutchinson Center's Public Health Sciences Division houses the Clinical Coordinating Center for the Women's Health Initiative, one of the most definitive, far-reaching studies of postmenopausal women's health ever undertaken in the United States. Enrollment began in 1993 and participants will be followed at least until 2010. The study examines the prevalence and risk factors for a number of diseases common in aging women, as well as the effects of various interventions, from low-fat diets and hormone therapy to calcium and vitamin D supplementation.

"We are extremely grateful for the study participants who have provided a wealth of biological data that will permit us to link genetic variants to relevant intermediate biomarkers that will potentially provide important clues to the biological basis of the disease," Kooperberg said.

Also collaborating on the project, in addition Kooperberg, Peters and colleagues from the WHI Clinical Coordinating Center, are investigators from the University of Arizona Cancer Center, Ohio State University and the University of Pittsburgh.

For more information about
'/>"/>

SOURCE Fred Hutchinson Cancer Research Center
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Fred Hutchinson Cancer Research Center and NSB POSTECH, Inc. to Collaborate on Development of New Class of Proteomic Microarrays
2. University of Miami Miller School of Medicine Becomes a GeneGo Center of Excellence
3. N.C. Biotech Center Launches Larger Loans
4. NorthPoint Domain and Boston Medical Center Partner to Apply Advanced Patient Engagement Instruments to Pioneering Cardiac Robotic Surgery Program
5. Yale Keck Microarray Center Becomes a GeneGo Center of Excellence
6. CET Life Sciences Center Welcomes Belmont University School of Pharmacy as New Tenant
7. N.C. Biotechnology Center Launches Industrial Fellowship Program
8. Worldwide Center for Adult Stem Cell Education LLC Changes Name to The Repair Stem Cell Institute LLC
9. U.S. Commerce Secretary Gutierrez Cuts Ribbon on MaxWell Biocorporations New Pharmaceutical Development Center and Quality Control Laboratory in Ukraine
10. TCN e-Systems Offers Trial Sponsors Solutions for Creating In-House Center of Excellence in Patient Recruitment
11. Spine Surgeons at Pine Creek Medical Center Take the Lead in Utilizing Stem Cell Technologies in Surgical Procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... April 21, 2015  Novogen Limited (ASX:NRT; NASDAQ: ... advises that it has entered into definitive agreements ... shares plus one attaching 6-month option and half ... share issued, to institutional investors in ... placement for aggregate gross proceeds of approximately AU$15,500,000 ...
(Date:4/21/2015)... April 21, 2015 A leading manufacturer ... is slated to discuss its custom fabrication services today ... reimagined website, which launched just prior to the INTERPHEX ... (April 21, 22 and 23) at the Javits Center ... of the world’s largest and most innovative pharmaceutical and ...
(Date:4/20/2015)... and Champaign, IL (PRWEB) April 20, 2015 ... the establishment of its 12th clinical research site: PMG ... Research has assumed operation of the clinical research department ... PMG’s footprint outside the Southeast to a second region ... a 150 multi-specialty physician practice enhances PMG’s access to ...
(Date:4/20/2015)... 20, 2015  "Everybody is affected by cancer sooner ... is frankly brutal. We,ve got to get away from ... or witnessed a loved one or friend battling for ... devastation chemotherapy and other treatments cause the human body. ... give up and succumb to the disease. Dr. Dionne ...
Breaking Biology Technology:Novogen Conducts Private Placement and Announces Rights Offering to Shareholders 2Novogen Conducts Private Placement and Announces Rights Offering to Shareholders 3Novogen Conducts Private Placement and Announces Rights Offering to Shareholders 4Novogen Conducts Private Placement and Announces Rights Offering to Shareholders 5Novogen Conducts Private Placement and Announces Rights Offering to Shareholders 6HOLLOWAY AMERICA to Reveal Newly Designed Responsive Website at INTERPHEX 2015 Today 2HOLLOWAY AMERICA to Reveal Newly Designed Responsive Website at INTERPHEX 2015 Today 3PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 2PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 3Is Dr. Craig Dionne the Steve Jobs of Cancer Research? 2
... might have left the ministry years ago, but he hasn't ... the author and speaker on all things Internet spotlights old ... them. , ,"The first requirement is to be willing ... those things about our culture that prevent us from encouraging, ...
... in the state will soon be able to ... Wisconsin Manufacturing Extension Partnership (WMEP) and the University ... which will bring e-business technologies to local manufacturers. ... supply chain collaboration among manufacturers and suppliers is ...
... people succeed and some fail at starting new businesses. As ... the world needs their new product or service, certain personality ... challenge. Its in the writing of their business plan that ... ,A good business plan is a road map for the ...
Cached Biology Technology:Dream Thieme 2Alliance Brings E-Business Technologies to Wisconsin Manufacturers 2Entrepreneurs and Business Plans 2
(Date:4/2/2015)... -- Fingerprint Cards (FPC) has received an ... distributor World Peace Industrial Group (WPI), part of WPG ... major part of the shipments will take place during ... manufacturers in China . The order ... revenue guidance of + 1 000 MSEK for 2015.  ...
(Date:4/1/2015)... 2015   Medisafe ™, the leading global medication ... iOS and Android smartphones and tablets, ... the platform to allow patients to track and correlate ... time, patients will be able to visualize in real-time ... biometrics, such as glucose levels and blood pressure. ...
(Date:3/31/2015)... --  Guidepoint , a leading global research services firm, ... TRACKER, part of the Guidepoint TRACKER suite ... device and therapeutics markets. The Post-Surgical Pain Management TRACKER ... share, and adoption rates across three major modalities used ... The Post-Surgical Pain Management TRACKER will provide length ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3
... A new research paper by a team of researchers ... (ECI) demonstrates how two cutting-edge technologies can provide a ... for invasive species before they get into our country ... cause ecological and economic damage worldwide, including the loss ...
... This press release is available in French . ... JUVS ) is a new quarterly, electronic-only publication that is now ... Fall of 2013. Developed in partnership with Unmanned Systems Canada (USC-STC) ... is an exciting addition to the NRC Research Press journal ...
... a negative impact on bees, ability to learn following exposure ... researchers found that the pesticides, used in the research at ... the learning circuits in the bee,s brain. They also found ... or completely forgot important associations between floral scent and food ...
Cached Biology News:Notre Dame researchers are using new technologies to combat invasive species 2NRC Research Press adds a new title to collection of scientific and technical journals 2Pesticide combination affects bees' ability to learn 2
... Assay is an anchorage-independent growth assay in ... stringent assay for detecting malignant transformation of ... with carcinogens or carcinogen inhibitors) are cultured ... for 21-28 days. Following this incubation ...
... BD CARV II Confocal Imager delivers high ... to use and cost effective optical package ... speed multi-point confocal scanning, combined with high ... allows real-time imaging and recording at up ...
... Gels easier and more efficient by providing ... types of pre-cut pre-assembled membrane/filter paper sandwiches ... cm E-PAGE Gels*. The available nitrocellulose and ... transfer of proteins (Figure 1 Table 1). ...
... x-ray detectors from KUBTEC represents a stand-alone, ... to 16 bit digital interface. The large ... sensor with pixel spacing down to 48 ... x-ray energies (10-50 kV) and an extended ...
Biology Products: