Navigation Links
Hurel Corporation Launches Cell-Based In Vitro Testing Product Suite, Milestone in Movement Away from Use of Live Animals in Drug and Toxicity Testing

NORTH BRUNSWICK, N.J., July 16, 2013 /PRNewswire/ -- Hurel Corporation ("Hurel"), a world-leading provider of advanced artificial tissue constructs and microfluidic cell-based assay platforms, today announced the commercial launch of its innovative in vitro product suite utilizing liver cells of the rat, dog and human species.  The announcement coincided with Hurel's Scientific Advisory Board Chairman Dr. Leslie Z. Benet's presentation of data generated using Hurel's products, which he gave at The Boston Society's HT-ADME 2013 conference, held today at the Broad Institute in Cambridge, Massachusetts.  The commercial availability of the Hurel products marks a milestone in the transition away from the use of live animals in drug and toxicity testing, towards new cell-based technologies that can substitute for and deliver more usefully predictive results than animal-based testing often can.

Hurel's cell-based products, respectively named HμRELHuman™, HμRELDog™, and HμRELRat™, are made from actual liver cells derived from the human, dog, or rat species.  The cells, which have previously been cryopreserved, are reconstituted and restored to functionality in Hurel's laboratories.  Formulated as a "co-culture" of two different, naturally occurring types of cells found in the liver, Hurel's products are distinctive for their high metabolic competency and responsiveness, the stability of their response levels day after day, and their long-lived endurance.  These attributes together enable researchers to perform kinds of experiments that may require a week or multiple weeks to carry out, cannot be completed in the limited span of days or hours afforded by the in vitro products in wide use today, and thus have frequently been conducted in live animals up until now. 

Dr. Benet's presentation at HT-ADME 2013 demonstrated, within the specific scientific arena of Drug Metabolism and Pharmacokinetics, that Hurel's products can provide greatly improved insight into drugs that take a long time to be biochemically broken down (metabolized) by the liver and thus "cleared" from the bodily system; can identify differences in the metabolite molecules that a drug produces when administered in humans, dogs, or rats, respectively; and can provide in vitro data that justifies the early elimination of inappropriate pre-clinical animal species from further use in the investigation of a particular pre-clinical drug candidate.   In sum, Dr. Benet's presentation demonstrated that Hurel's products represent an important step in the pathway of reducing animal tests and substituting them with in vitro cell-based tests.

"Recently, the nation's attention was riveted by the news that the National Institutes of Health is retiring its chimpanzees from further use in biomedical research.  Hurel is pleased to demonstrate that its cell-based products comprise powerful, broadly applicable new tools that in many applications are not only more effective and predictive than existing in vitro methods, but are also more effective and predictive than live animal testing, and thus afford the technological means to extend the NIH's reduction in the use of lab animals to include increasing numbers of animals of other species in addition to chimps," said Robert Freedman, Hµrel's Chairman and CEO.  "Hurel's launch of the HμRELHuman™, HμRELDog™, and HμRELRat™ product line helps respond to the needs of society, the regulatory agencies and industry to reduce the extent of animal testing in drug development."

About Hurel
Hurel Corporation, based in North Brunswick, NJ and Beverly Hills, CA, is a world-leading provider of advanced artificial tissue constructs and microfluidic cell-based assay platforms that are used by major pharmaceutical research organizations in pre-clinical drug development, as well as in the toxicological testing of industrial materials and consumer products.  Hurel recently consummated a $9.2 million Series A preferred stock financing facility led by Spring Mountain Capital, in which the Humane Society of the United States is also a participant.  In addition to its currently offered line of HμRELHuman™, HμRELDog™, and HμRELRat™ products, the company is also developing HμRELFlow™, which augments the power of its cell-based technologies through the addition of microfluidics.  More information about Hurel can be found at

SOURCE Hurel Corporation
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. China Cord Blood Corporation to Report Second Quarter and First Half of Fiscal 2012 Financial Results
2. Kensey Nash Corporation Announces Achievement of $6 Million Milestone From Spectranetics Corporation
3. China Cord Blood Corporation Announces Results of 2011 Annual General Meeting
4. Neogen Corporation Announces 2nd Quarter Results Conference Call
5. Luminex Corporation to Present at JP Morgan Healthcare Conference
6. Luminex Corporation Fourth Quarter and Full Year 2011 Earnings Release Scheduled for February 6, 2012
7. Plaintiff Sales Representatives and Novartis Pharmaceuticals Corporation Resolve Class Action Wage and Hour Claims
8. JBT Corporation and Swisslog Enter Into Partnership for Automated Guided Vehicles
9. China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012
10. Verenium Corporation to Announce Fourth Quarter and Year-End 2011 Financial Results
11. Luminex Corporation to Speak at Joint Department of Defense and Environmental Protection Agency 5th National Bio-Threat Conference
Post Your Comments:
(Date:11/24/2015)... 24, 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: ... the remaining 11,000 post-share consolidation (or 1,100,000 pre-share ... "Series B Warrants") subject to the previously disclosed ... 23, 2015, which will result in the issuance ... to the issuance of such shares, there will ...
(Date:11/24/2015)... QC , Nov. 24, 2015 /CNW Telbec/ - ProMetic ... "Corporation") announced today that Mr. Pierre Laurin , President ... corporate presentation at the upcoming Piper Jaffray 27 th ... Palace Hotel, on December 1-2, 2015. st ... available for one-on-one meetings throughout the day. The presentation will ...
(Date:11/24/2015)... ... ... Whitehouse Laboratories is pleased to announce that it has completed construction on a new ... USP 61, USP 62 and USP 51 testing specific to raw materials and will ... performed by one supplier. Management has formally announced that the facility will ...
(Date:11/23/2015)... ... November 23, 2015 , ... Shimadzu ... of its Nexera UC Unified Chromatography system. The award from R&D magazine recognizes ... products of the year in the analytical and testing category. R&D Magazine chose ...
Breaking Biology Technology:
(Date:10/29/2015)...  Connected health pioneer, Joseph C. Kvedar , ... health and wellness, and the business opportunities that arise ... Internet of Healthy Things . Long before health ... Dr. Kvedar, vice president, Connected Health, Partners HealthCare, was ... care from the hospital or doctor,s office into the ...
(Date:10/29/2015)... YORK , Oct. 29, 2015 ... technology, announced a partnership with 2XU, a global ... to deliver a smart hat with advanced bio-sensing ... and other athletes to monitor key biometrics to ... the strategic partnership, the two companies will bring together ...
(Date:10/27/2015)... 27, 2015 Munich, Germany ... Mapping technology (ASGM) automatically maps data from mobile eye ... , so that they can be quantitatively analyzed ... Munich, Germany , October 28-29, 2015. SMI,s ... from mobile eye tracking videos created with SMI,s ...
Breaking Biology News(10 mins):