Navigation Links
Human brains share a consistent genetic blueprint and possess enormous biochemical complexity
Date:9/19/2012

both during the lifespan and throughout evolution.
  • The right and left hemispheres show no significant differences in molecular architecture. This suggests that functions such as language, which are generally handled by one side of the brain, likely result from more subtle differences between hemispheres or structural variation in size or circuitry, but not from a deeper molecular basis.
  • Despite controlling a diversity of functions, ranging from visual perception to planning and problem-solving, the cortex is highly homogeneous relative to other brain regions. This suggests that the same basic functional elements are used throughout the cortex and that understanding how one area works in detail will uncover fundamentals that apply to the other areas, as well.
  • In addition to such global findings, the study provides new insights into the detailed inner workings of the brain at the molecular level the level at which diseases unfold and therapeutic drugs take action.
  • 84% of all genes are expressed, or turned on, somewhere in the human brain.
  • Many previously uncharacterized genes are turned on in specific brain regions and localize with known functional groups of genes, suggesting they play roles in particular brain functions.
  • Synapse-associated genes those related to cell-to-cell communication machinery in the brain are deployed in complex combinations throughout the brain, revealing a great diversity of synapse types and remarkable regional variation that likely underlies functional distinctions between brain regions.

    "The tremendous variety of synapses we see in the human brain is quite striking," said Seth Grant, FRSE, Professor of Molecular Neuroscience at the University of Edinburgh and collaborating author on the study. "Mutations in synaptic genes are associated with numerous brain-related disorders, and thus understanding synapse diversity and organization in the brain is a key step toward understanding these d
    '/>"/>


  • Contact: Steven Cooper
    press@alleninstitute.org
    646-358-2765
    Allen Institute for Brain Science
    Source:Eurekalert

    Page: 1 2 3

    Related biology technology :

    1. PROLOR Biotech To Present Data On Its Long-Acting Human Growth Hormone At International NeuroEndocrine Meeting
    2. Preclinical data shows 100 percent prevention and treatment of influenza with engineered human antibody
    3. Millions of DNA switches that power human genomes operating system are discovered
    4. Human Genome Decoder and Artificial Life Creator, J. Craig Venter to Speak at "The Atlantic Meets the Pacific"
    5. MO BIO Laboratories, Inc. Becomes Exclusive Sponsor Of Natures Human Microbiota Special
    6. Global water sustainability flows through natural and human challenges
    7. Oncobiologics, Inc. Announces a Collaboration Agreement with XOMA Corporation to Utilize XOMAs Fully Human Antibody Libraries for Their Discovery Platform
    8. Published Findings In Human Gene Therapy Methods Journal Demonstrate Cardiums New Catheter-Based Method Significantly Boosts Gene Delivery To The Heart
    9. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
    10. Chemical makes blind mice see; compound holds promise for treating humans
    11. HemoShear Partners with Expression Analysis (EA) to Develop a Human Drug-Induced Vascular Response Database
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:12/24/2014)... Pipette.com announces their Holiday in ... submit their #HolidayInTheLab pictures for a chance to win ... For those struggling to think of a holiday gift ... the Lab Contest provides the ideal holiday presents. The ... send pictures of their chemistree, holiday sweaters, as well ...
    (Date:12/24/2014)... , Dec. 23, 2014  Rock Creek Pharmaceuticals, ... it has filed a Clinical Trial Application (CTA) with ... products Regulatory Agency (MHRA) seeking regulatory approval to initiate ... molecule, Anatabine Citrate. Contingent on the Company ... a Phase I trial to assess the safety, tolerability ...
    (Date:12/22/2014)... CHAPEL HILL, N.C. , Dec. 22, 2014 ... ALNE) today announced that it has signed a ... biotechnology company that has developed and patented a ... and medical diagnostics products that enable rapid on-site ... and alcohol use/abuse and health issues in an ...
    (Date:12/22/2014)... Fertility Associates of Memphis has announced a new ... network of more than 20 contributing fertility practices ... access to a national pool of frozen donor ... of Memphis is the only fertility clinic in the ... Dr. William Kutteh , director of Fertility Associates of ...
    Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3ALNE Announces Intention To Acquire BioTechPharma 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
    ... Everyone wants to design the dsRNA that , ... length correlate with silencing efficiency? Ambion scientists , ... dsRNA of different sizes and directed , ... (Figure 1A), were prepared using the MEGAscript RNAi Kit ...
    ... Large scale gene expression studies , ... purify high quality RNA from a large number of samples. Although the , ... dsRNA production and , clean up, ... format. Thus for high-throughput applications, we recommend , ...
    ... , ... heterogenous samples is a major challenge in studying gene , ... microdissection (LCM), developed in a collaborative ... and Arcturus, Inc. specifically to isolate , ...
    Cached Biology Technology:RNAi: Size Does Matter 2RNAi for High Throughput Analysis 2RNA from LCM Samples 2RNA from LCM Samples 3
    (Date:11/21/2014)... REDMOND, Wash. , Nov. 20, 2014 ... access for the Internet of Things (IoT), today announced ... position of chief operating officer. Previously a strategic advisor ... marketing, finance, and operations. Mr. Traynor is based out ... . He reports to Chris Muench , ...
    (Date:11/18/2014)... WASHINGTON , Nov. 18, 2014  The ... Security Industry Association today jointly announce the formation ... and release of its Identity and Biometric ... (Framework). The Framework received official support from BORDERPOL, ... governments to improve and provide expertise regarding border ...
    (Date:11/18/2014)... 2014 The Parenteral Drug Association (PDA) today confirmed ... speak and at least seven more will participate in the ... Shoreham Hotel in Washington D.C. , Dec. ... significant support from the regulatory agencies in the ... in our effort to help advance the use of metrics ...
    Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
    ... percent of mares have difficulties conceiving. The most common cause ... the mucusal membrane of the uterus caused by the bacteria ... noticed that many horses that test negative for streptococci have ... of symptoms, however, it still seems to reduce the fertility ...
    ... richer the assortment of amphibian species living in a pond, ... has against a parasitic infection that can cause severe deformities, ... study by the University of Colorado Boulder. The ... support the idea that greater biodiversity in larger-scale ecosystems, such ...
    ... NY. (Feb. 13, 2013) Researchers at the Johns ... Research Centre in Warsaw, Poland, have found that nonself-donated ... immunocompetent research mice when the grafts are injected into ... into the forceps minor (FM) region. In their ...
    Cached Biology News:Researchers make racehorses fertile 2CU-Boulder amphibian study shows how biodiversity can protect against disease 2CU-Boulder amphibian study shows how biodiversity can protect against disease 3CU-Boulder amphibian study shows how biodiversity can protect against disease 4Impact of stem cell transplantation location in brain a crucial factor for cell survival 2
    MAb to HLA, Class II-DR+DP Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business Days...
    ... surface is produced by a patented microwave ... giving more consistent, even cell attachment, increased ... attachment and growth uunder difficult conditions, including ... may provide a more ecominic alternative to ...
    ... array system, 100-240 V, uses multiplex suspension ... analysis of up to 100 proteins and ... suspension array is composed of up to ... may be conjugated with a unique reactant ...
    ... PYREX Delong style shaker flasks have three ... agitation of solutions to improve oxygen or ... reciprocating shakers. The long neck reduces splashing ... Their uniform wall thickness provides the proper ...
    Biology Products: