Navigation Links
Human Genome Sciences Announces Initiation of Phase 2b Trial of Albuferon(R) Dosed Monthly in Chronic Hepatitis C
Date:1/12/2009

- Trial conducted by Novartis to evaluate safety and efficacy of Albuferon administered every four weeks in combination with ribavirin in patients with genotypes 2 and 3 hepatitis C -

ROCKVILLE, Md., Jan. 12 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI) today announced that Novartis has initiated dosing in a Phase 2b trial that will evaluate the safety and efficacy of Albuferon(R) (albinterferon alfa-2b) administered monthly in combination with ribavirin in treatment-naive patients with genotypes 2 and 3 chronic hepatitis C. Albuferon is being developed by HGS and Novartis under an exclusive worldwide co-development and commercialization agreement entered into in June 2006.

(LOGO: http://www.newscom.com/cgi-bin/prnh/20080416/HGSLOGO )

"Patients undergoing treatment for chronic hepatitis C often find it challenging to participate in normal daily activities, especially in the days following dose administration," said Stephen Pianko, M.D., F.R.A.C.P., Ph.D., Monash University, Melbourne, Australia. "Pegylated interferons, the current standard of care, require administration once every week. Albinterferon alfa-2b dosed every four weeks with a total of six injections could offer an important treatment option, if it demonstrates comparable safety and efficacy vs. peginterferon alfa-2a dosed weekly with a total of 24 injections."

In December 2008, HGS announced that Albuferon met its primary endpoint of non-inferiority to peginterferon alfa-2a (Pegasys) in ACHIEVE 2/3, a Phase 3 clinical trial of Albuferon in combination with ribavirin in treatment-naive patients with genotypes 2 and 3 chronic hepatitis C. In these patients, the Phase 3 study showed that 900-mcg Albuferon administered every two wee
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Expiry of Hart-Scott-Rodino Waiting Period for JUVISTA(R) (Human TGF BETA 3)
2. New Initiative Has Shocking Effect: Thousands of Missourians with Abnormal Chromosome Structures Are Not Human
3. ExonHit Therapeutics: Allergan and ExonHits First Collaboration Compound to Begin Human Clinical Trials
4. Human Genome Sciences Announces $40 Million Milestone Payment Related to Albuferon(R) Development
5. Novocell Announces Discovery Linking Key Cancer Cell Signaling Pathways With Proliferation and Self-Renewal of Human Embryonic Stem Cells
6. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Thomas Weisel Partners Conference
7. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at BioCentury-Thomson Financial Investment Conference
8. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Bear Stearns Conference
9. Human Pheromone Sciences Enters Into Agreement to Reposition and Promote its Natural Attraction(R) Brand
10. Human Genome Sciences Invites Investors to Listen to Webcast of Presentation at Merrill Lynch Conference
11. Premier Research Appoints Global Head of Human Resources

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...Nov. 25 /PRNewswire/ - Cytochroma today announced ...f Directors. Dr. Moldt will replace Mr. Ulrik Spor...Board. The number of Board members remains unchang...elcome Peter Moldt to the board and look forward t...ytochroma continues to make progress in becoming a...
(Date:11/25/2009)...K, Nov. 25 Reportlinker.com announ... in its catalogue: ,, Brazil Bioethanol Market....reportlinker.com/p0165503/Brazil-Bioethanol-Marke...l Bioethanol Market Analysis and Forecasts to 2013...d analysis and forecasts of the global bioethanol ...
(Date:11/24/2009)...ble in German . , Whether it,s CD packaging...adio Frequency Identification) are increasingly fi...ossible to label objects or goods and identify the...e scanner can read and process the data contained ... under production conditions of up to 100 degrees ...
(Date:11/24/2009)... Ambassador to also Visit Detroit , ...David Appia, French Ambassador for International I...rance Agency, , , , ,What: Ambassador Appia is av...usiness initiatives adopted by France to further d...e for innovation and development., , ,When: Availa...
Breaking Biology Technology:Cytochroma Announces Appointment of Peter Moldt to Board of Directors 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 3Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 4Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 5Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 6Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 7Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 8Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 9Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 10Intelligence inside metal components 2
...up, a life science-focused strategic communication...d as public relations agency of record by therapeu...nces, Inc. , , Donna L. LaVoie, President & ...to represent Profectus during an important stage i...ward to working with them to communicate their mes...
... work could help farmers protect against billions ... St. Louis, MO (PRWEB) April 29, 2009 -- In the pa..., has received more than $1.2 million in research ...om the National Science Foundation (NSF) to furthe...nematode control in crops such as corn. The Phase...
..., Inc. (Nasdaq: TELK ) announced results of stud...ere presented at the 100th annual meeting of the A...Denver, CO. The abstracts can be found on the Tel...haracterization and Mechanism of Action of Orally ... 1764 , Aurora kinases are Ser/Thr kinases that p...
Other Biology Technology:LaVoie Group Selected by Vaccine Developer, Profectus BioSciences, as Agency of Record 2Divergence Receives $1.2 Million in Grants, Including NSF Grant to Fund Continuing Nematode Research in Corn 2Divergence Receives $1.2 Million in Grants, Including NSF Grant to Fund Continuing Nematode Research in Corn 3Telik Reports Preclinical Results at AACR Annual Meeting 2Telik Reports Preclinical Results at AACR Annual Meeting 3
(Date:11/24/2009)... , Rocket science is opening new doors to underst... affect the hearing of a marine mammal or if they...rial sized X-ray scanners that NASA uses to detect...rockets is now allowing scientists to peek inside ... detailed three-dimensional replicas of a whale,s ...
(Date:11/24/2009)... , Springer and the American College of Medical T...borate on the publication of the Journal of Medic...ACMT, beginning in March 2010. It was previously ... , The Journal of Medical Toxicology , an inte...advancing the science and practice of medical toxi...
(Date:11/24/2009)... , Cambridge, Md. (November 24, 2009) New resear...rctic river ecosystems reveals predictable tempora...hese communities as markers for monitoring climate... this week in the Proceedings of the National Aca...ial communities in the six rivers shifted synchron...
Breaking Biology News(10 mins):Rocket science leads to new whale discovery 2Springer and the American College of Medical Toxicology to work together 2Researchers establish common seasonal pattern among bacterial communities in Arctic rivers 2New Survey Identifies Specialized Training and Respect for Culture as Key Factors in Healthcare Security Personnel Selection 54068 1New Survey Identifies Specialized Training and Respect for Culture as Key Factors in Healthcare Security Personnel Selection 54068 2Enfina Healthcare Solutions Implements Business Process Outsourcing Services Software from DST Health Solutions 54066 1Enfina Healthcare Solutions Implements Business Process Outsourcing Services Software from DST Health Solutions 54066 2Latest Holiday Migraine Survey Results Published 54065 1Latest Holiday Migraine Survey Results Published 54065 2Latest Holiday Migraine Survey Results Published 54065 3
...ug abusers are increasingly turning to a slow-rele...dangerous high, University of Florida researchers ...people dying from an overdose of the drug fentanyl...ises. , Addicts are misusing a clear patch that tr...skin into the bloodstream over the course of a few...
...new website with a Global Information System will ...mental hazards caused by Hurricane Katrina. The Na...(NIEHS), one of the National Institutes of Health,...e data to public health and safety workers on cont...try maps, as well as demographic information for l...
...new website with a Global Information System will ...mental hazards caused by Hurricane Katrina. The Na...(NIEHS), one of the National Institutes of Health,...e data to public health and safety workers on cont...try maps, as well as demographic information for l...
Other Biology News:Prescription pain patch abuse blamed for increase in deaths 2Prescription pain patch abuse blamed for increase in deaths 3FDA approves child-friendly AIDS medicine 2NIEHS launches website with information for assessing environmental hazards from Hurricane Katrina 2
... was tested on rat tissue extracts (liver, kidney,...) extract. It was also tested with microsomal frac...plication: A simple and reliable method for measur...d on the detection of the inorganic phosphate rele...
...ve stress is the condition in which a lack of bala...ious antioxidants. Oxidative stress appears to be... including artherosclerosis, chronic inflammatory ...s several antioxidant systems that are very import...
FlowJo from Tree Star Inc
...ytic degradation is critical to the maintenance of...proteins as important and diverse as those involve...sponse, antigen presentation, modulation of cell s...lation, transcription, and signalling factors. The...
Biology Products: