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Human Genome Sciences Announces Closing of Public Offering
Date:8/3/2009

ectus-ny@ny.email.gs.com>prospectus-ny@ny.email.gs.com and Citigroup Global Markets Inc. at Brooklyn Army Terminal, 140 58(th) Street, 8(th) Floor, Brooklyn, NY 11220, Attention: Prospectus Department, 800-831-9146.

About Human Genome Sciences

Human Genome Sciences is a commercially focused biopharmaceutical company. In the first half of 2009, HGS achieved its first product revenues of $162.7 million when we delivered raxibacumab (ABthrax(TM)) to the U.S. Strategic National Stockpile for the treatment of inhalation anthrax. HGS has two other products in late-stage clinical development: ZALBIN(TM) (formerly Albuferon((R))) for chronic hepatitis C and BENLYSTA(TM) (formerly LymphoStat-B((R))) for systemic lupus erythematosus.

For more information about HGS, please visit the Company's web site at www.hgsi.com. Health professionals and patients interested in clinical trials of HGS products may inquire via e-mail to medinfo@hgsi.com or by calling HGS at (877) 822-8472.

HGS, Human Genome Sciences, ABthrax, Albuferon, BENLYSTA, LymphoStat-B, and ZALBIN are trademarks of Human Genome Sciences, Inc.

Safe Harbor Statement

This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The forward-looking statements are based on Human Genome Sciences' current intent, belief and expectations. These statements are not guarantees of future performance and are subject to certain risks and uncertainties that are difficult to predict. Actual results may differ materially from these forward-looking statements because of Human
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SOURCE Human Genome Sciences, Inc.
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